Etofenamate

Product Name: Etofenamate
CAS No.: 30544-47-9
Chemical Name: Etofenamate
Synonyms: ReuMon;TV-485;Rheumon;TVX-485;CS-1431;Bayrogel;Etofenate;Etofenamate;TrauMon Gel;Ethofenamate
CBNumber: CB6883241
Molecular Formula: C18H18F3NO4
Formula Weight: 369.33
MOL File: 30544-47-9.mol

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Etofenamate Property

Melting point:: 25°C
Boiling point:: bp.001 130-135°
Density: 1.2866 (estimate)
refractive index: nD25 1.564
storage temp.: Sealed in dry,2-8°C
solubility: Practically insoluble in water, miscible with ethanol (96 per cent) and with ethyl acetate.
pka: 14.32±0.10(Predicted)
form: Oil
color: Light yellow to yellow
Stability:: Light Sensitive

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Safety

RIDADR: UN2810 - class 6.1 - PG 3 - EHS - Toxic, liquids, organic, n.o.s., HI: all
Toxicity: LD50 in male, female rats (mg/kg): 292, 470 orally; 140, 226 i.v.; 373, 397 i.p.; 643, 568 s.c. (Jacobi)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H410Very toxic to aquatic life with long lasting effects

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E2499901
Product name: Etofenamate for peak identification
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e2499901
Price: $153
Updated: 2024/03/01

Sigma-Aldrich

Product number: E2499900
Product name: Etofenamate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: e2499900
Price: $150
Updated: 2024/03/01

Cayman Chemical

Product number: 23674
Product name: Etofenamate
Purity: ≥98%
Packaging: 50mg
Price: $89
Updated: 2024/03/01

Cayman Chemical

Product number: 23674
Product name: Etofenamate
Purity: ≥98%
Packaging: 100mg
Price: $141
Updated: 2024/03/01

Cayman Chemical

Product number: 23674
Product name: Etofenamate
Purity: ≥98%
Packaging: 250mg
Price: $264
Updated: 2024/03/01

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Etofenamate Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Oil

Originator

Rheumon,Troponwerke,W. Germany,1977

Uses

As a histamine H1 -receptor antagonist, Etofenamate can be used as anti-inflammatory;cyclooxygenase inhibitor and medication used to alleviate joint and muscle pain.

Definition

ChEBI: 2-[3-(trifluoromethyl)anilino]benzoic acid 2-(2-hydroxyethoxy)ethyl ester is a benzoate ester.

Manufacturing Process

16.0 g (0.05 mol) of the potassium salt of N-(3-trifluoromethylphenyl)- anthranilic acid are dissolved in 60 ml of dimethylformamide and heated to 110°C, and 6.2 g (0.05 mol) of 2-(2-chloroethoxy)-ethanol are slowly added. The reaction mixture is then heated to boiling for 2 hours. The precipitated potassium chloride is filtered off and the solvent is removed by evaporation. The residue is separated over a column with 400 g of silica gel (particle size 0.05 to 0.2 mm), using a 1:1 mixture of cyclohexane and glacial acetic acid as eluting agent. 16.0 g of the 2-(2-hydroxyethoxy)-ethyl ester of N-(3- trifluoromethylphenyl)-anthranilic acid are obtained in the form of a pale yellow oil which does not crystallize and cannot be distilled.

Therapeutic Function

Antiinflammatory

Etofenamate Preparation Products And Raw materials

Raw materials

Preparation Products

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Etofenamate Suppliers

Canada 1 China 121 France 1 Germany 3 India 6 South Korea 1 Spain 2 United States 17 Global 152

MedChemexpress LLC

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Target molecule Corp.

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TargetMol Chemicals Inc.

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InvivoChem

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Aladdin Scientific

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Aceschem Inc.

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Cayman Chemical Company

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MedChemExpress

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Combi-Blocks Inc.

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Riedel-de Haen AG

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View Lastest Price from Etofenamate manufacturers

Dideu Industries Group Limited

Product: Etofenamate 30544-47-9
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-06-15

Career Henan Chemical Co

Product: Etofenamate 30544-47-9
Price: US $5.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-09-03

30544-47-9, EtofenamateRelated Search:

Etomidate 3-Diethylaminophenol Benzyl benzoate FLURBIPROFEN AXETIL Denatonium Benzoate Anhydrous Ethyl acetate 2'-Hydroxy-3-phenylpropiophenone 2-(Dimethylamino)ethyl (4-chlorphenoxy)acetate Meclofenoxate hydrochloride Ethanol Phenetidine Sodium benzoate Ethyl acrylate Butylparaben Ethylparaben ISOXADIFEN-ETHYL 3-Hydroxybenzoic acid Salicylic acid

EtofenamateEtofenamate

2-(2-hydroxyaethoxy)aethylester der flutenaminsaeure

2-(2-hydroxyethoxy)ethyl-n-(alpha,alpha,alpha-trifluoro-m-tolyl)anthrani late

Benzoic acid, 2[[3-(trifluoromethyl)phenyl]amino]-2-(hydroxyethoxy)ethyl ester

n-(alpha,alpha,alpha-trifluoro-m-tolyl)-anthranilic acid 2-(2-hydroxyethoxy)

2-(2-Hydroxyethoxy)ethyl 2-[3-(trifluoromethyl)anilino]benzoate

Ethofenamate

Rheumon

Etofenamate

2-(2-Hydroxyethoxy)ethyl FufenaMate

2-[[3-(TrifluoroMethyl)phenyl]aMino]benzoic Acid 2-(2-Hydroxyethoxy)ethyl Ester

Bayrogel

ReuMon

TrauMon Gel

2-(2-hydroxyethoxy)ethyl 2-((3-(trifluoroMethyl)phenyl)aMino)benzoate

EtofenaMate,TV-485

TV-485

TVX-485

Etofenamate, >=98%

CS-1431

Etofenamate CRS

Etofenamate for peak identification CRS

Benzoic acid, 2-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester

Etofenamate USP/EP/BP

Etofenate

Etofenamate, 10 mM in DMSO

30544-47-9

Inhibitors

Amines

Aromatics

Intermediates & Fine Chemicals

Pharmaceuticals