ChemicalBook > CAS DataBase List > 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester

15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester

Product Name: 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
CAS No.: 459426-22-3
Chemical Name: 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester
Synonyms: Biotin-PEG4-NHS;NHS-dPEG ®NHS-PEG4-Biotin;Biotin-PEG4-SPA;NHS-dPEG4-Biotin;NHS-dPEG(R)4-biotin;Biotin-PEG4-NHS ester;(+)-Biotin-PEG4-NHS Ester;Biotin-PEG4-NHS-propionate;NHS-dPEG??-biotin (QBD-10200)
CBNumber: CB72546806
Molecular Formula: C25H40N4O10S
Formula Weight: 588.67
MOL File: 459426-22-3.mol

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15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Property

Density: 1.33±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: Soluble in DMSO, DMF, DCM
form: solid or viscous liquid
pka: 13.90±0.40(Predicted)
color: White to light yellow
Appearance: white to off-beige powder
InChIKey: DTLVBHCSSNJCMJ-JXQFQVJHSA-N
SMILES: C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@H]1[C@@]2([H])NC(=O)N[C@@]2([H])CS1

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: QBD10200
Product name: NHS-dPEG®4-biotin
Packaging: 50MG
Price: $168
Updated: 2025/07/31

Sigma-Aldrich

Product number: QBD10200
Product name: NHS-dPEG®4-biotin
Packaging: 1000 mg
Price: $1090
Updated: 2025/07/31

Sigma-Aldrich

Product number: QBD10200
Product name: NHS-dPEG®4-biotin
Packaging: 1000 mg
Price: $1090
Updated: 2025/07/31

Cayman Chemical

Product number: 29114
Product name: Biotin-PEG4-NHS
Packaging: 25mg
Price: $65
Updated: 2024/03/01

Cayman Chemical

Product number: 29114
Product name: Biotin-PEG4-NHS
Packaging: 50mg
Price: $121
Updated: 2024/03/01

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15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Chemical Properties,Usage,Production

Description

Biotin-PEG₄-NHS is an amine reactive reagent that contains biotin linked via a four-unit PEG spacer to N-hydroxysuccinimide (NHS), which facilitates the coupling of biotin to primary amines. Biotin-PEG₄-NHS has been used in the biotinylation of proteins and antibodies.

Uses

Biotin-PEG4-NHS ester is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

reaction suitability

reagent type: cross-linking reagent
reaction type: Biotinylations
reactivity: amine reactive
reagent type: linker

IC 50

PEGs

References

[1] Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13(5):514-521. DOI:10.1038/nchembio.2329

15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Biotin-PEG4-NHS ester 459426-22-3
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-30

459426-22-3, 15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl esterRelated Search:

15-[D(+)-BIOTINYLAMINO]-4,7,10,13-TETRAOXAPENTADECANOIC ACID Biotin-PEG3-CH2COOH 1H-Thieno[3,4-d]imidazole-4-pentanamide,N-(14-amino-3,6,9,12-tetraoxatetradec-1-yl)hexahydro-2-oxo-,(3aS,4S,6aR)- Biotin-PEG5-SH Biotin-PEG5-Amine Biotin-PEG4-TFP H2N-PEG2-tBu BOC-15-AMINO-4,7,10,13-TETRAOXAPENTADECANOIC ACID N3-PEG4-tBu Maleimide-PEG4-NHS Ester 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47-Hexadecaoxanonatetracontan-49-ol 3,6,9,12,15,21,24,27,30-Decaoxadotriacontane-1,32-diaMine HO-PEG5-tBu ALPHA,OMEGA-BIS(2-CARBOXYETHYL)POLYETHYLENE GLYCOL 10'000 Succinimidyl 6-(biotinamido)hexanoate (+)-Biotin-PEG12-CH2CH2COONHS Ester OCTAETHYLENE GLYCOL MONOMETHYL ETHER Biotin-PEG3-NHS ester

NHS-PEG4-Biotin

NHS-dPEG4-Biotin

21-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-4,7,10,13-tetraoxa-16-azaheneicosanoic acid 2,5-dioxo-1-pyrrolidinyl ester

Biotin-PEG4-NHS ester

Biotin PEG4 succinimidyl ester

NHS-dPEG(R)4-biotin

Biotin-PEG4-NHS-propionate

15-biotinlaMino-4,7,10,13-dioxanonanoic acid N-hydroxysucciniMidyl ester

Biotin-PEG4-NHS

Biotin-PEG4-CH2CH2COONHS Ester

4,7,10,13-Tetraoxa-16-azaheneicosanoic acid, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-17-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

Biotin-PEG4-SPA

(+)-Biotin-PEG4-NHS Ester

NHS-dPEG &reg

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]propanoate

NHS-dPEG?4-biotin

Biotin-PEG4-NHS Ester (CCT-B103)

NHS-dPEG??-biotin (QBD-10200)

459426-22-3

C25H40N4O10S

SiChem

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