ML234

Product Name: ML234
CAS No.: 1222800-79-4
Chemical Name: ML234
Synonyms: ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;NCGC00183808-01;ML234 USP/EP/BP;ML-324;ML324;ML 324;ML324(CID-44143209)
CBNumber: CB72744613
Molecular Formula: C21H23N3O2
Formula Weight: 349.43
MOL File: 1222800-79-4.mol

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ML234 Property

Melting point:: >187oC (dec.)
Boiling point:: 590.1±50.0 °C(Predicted)
Density: 1.188±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
solubility: DMSO: soluble10mg/mL, clear
form: powder
pka: 4.71±0.40(Predicted)
color: white to light brown
Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0741
Product name: ML324
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $85.8
Updated: 2024/03/01

Sigma-Aldrich

Product number: SML0741
Product name: ML324
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $430
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 5mg
Price: $70
Updated: 2024/03/01

Cayman Chemical

Product number: 17472
Product name: ML-324
Purity: ≥95%
Packaging: 10mg
Price: $109
Updated: 2024/03/01

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ML234 Chemical Properties,Usage,Production

Description

ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1

Uses

ML324 is a JMJD2 demethylase inhibitor. It blocks the initiation of viral lytic infection and HSV-1 reactivation in the sensory ganglia of latently infected mice.

References

1) Liang?et al. (2013),?Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med.,?5?167ra5

ML234 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML234 Suppliers

China 78 India 1 The Netherlands 1 United States 16 Global 96

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2922
Advantage: 55

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: meilunui@163.com
Country: China
ProdList: 4727
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

AdooQ Bioscience CHINA

Tel: 025-58849295 18951903616;
Fax: 025-68650336
Email: info@adooq.cn
Country: China
ProdList: 2990
Advantage: 60

Cool Pharm, Ltd

Tel: 021-60455363 18019463053
Fax: 50966098
Email: sales@coolpharm.com
Country: China
ProdList: 12346
Advantage: 58

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

D&C Chemicals

Tel: +86-21-58447131
Fax: +86-21-61642470
Email: 1724405207@qq.com
Country: China
ProdList: 472
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6463
Advantage: 55

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9806
Advantage: 58

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View Lastest Price from ML234 manufacturers

Career Henan Chemical Co

Product: ML234 1222800-79-4
Price: US $1.00/g
Min. Order: 1g
Purity: 99%
Supply Ability: 20kg
Release date: 2019-12-23

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ML234

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N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide

NCGC00183808-01

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ML234 USP/EP/BP

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ML324, ML-324

1222800-79-4

Inhibitors