ML234
- Product Name
- ML234
- CAS No.
- 1222800-79-4
- Chemical Name
- ML234
- Synonyms
- ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;NCGC00183808-01;ML234 USP/EP/BP;ML-324;ML324;ML 324;ML324(CID-44143209)
- CBNumber
- CB72744613
- Molecular Formula
- C21H23N3O2
- Formula Weight
- 349.43
- MOL File
- 1222800-79-4.mol
ML234 Property
- Melting point:
- >187oC (dec.)
- Boiling point:
- 590.1±50.0 °C(Predicted)
- Density
- 1.188±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- pka
- 4.71±0.40(Predicted)
- color
- white to light brown
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML0741
- Product name
- ML324
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $85.8
- Updated
- 2024/03/01
- Product number
- SML0741
- Product name
- ML324
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $430
- Updated
- 2024/03/01
- Product number
- 17472
- Product name
- ML-324
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17472
- Product name
- ML-324
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $70
- Updated
- 2024/03/01
- Product number
- 17472
- Product name
- ML-324
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
ML234 Chemical Properties,Usage,Production
Description
ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1
Uses
ML324 is a JMJD2 demethylase inhibitor. It blocks the initiation of viral lytic infection and HSV-1 reactivation in the sensory ganglia of latently infected mice.
References
1) Liang?et al. (2013),?Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med.,?5?167ra5
ML234 Preparation Products And Raw materials
Raw materials
Preparation Products
ML234 Suppliers
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View Lastest Price from ML234 manufacturers
- Product
- ML234 1222800-79-4
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 20kg
- Release date
- 2019-12-23