ChemicalBook > CAS DataBase List > ML234

ML234

Product Name
ML234
CAS No.
1222800-79-4
Chemical Name
ML234
Synonyms
ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;NCGC00183808-01;ML234 USP/EP/BP;ML-324;ML324;ML 324;ML324(CID-44143209)
CBNumber
CB72744613
Molecular Formula
C21H23N3O2
Formula Weight
349.43
MOL File
1222800-79-4.mol
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ML234 Property

Melting point:
>187oC (dec.)
Boiling point:
590.1±50.0 °C(Predicted)
Density 
1.188±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO: soluble10mg/mL, clear
form 
powder
pka
4.71±0.40(Predicted)
color 
white to light brown
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
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Safety

Hazard Codes 
Xn
Risk Statements 
22
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0741
Product name
ML324
Purity
≥98% (HPLC)
Packaging
5mg
Price
$85.8
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0741
Product name
ML324
Purity
≥98% (HPLC)
Packaging
25mg
Price
$430
Updated
2024/03/01
Cayman Chemical
Product number
17472
Product name
ML-324
Purity
≥95%
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
17472
Product name
ML-324
Purity
≥95%
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
17472
Product name
ML-324
Purity
≥95%
Packaging
10mg
Price
$109
Updated
2024/03/01
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ML234 Chemical Properties,Usage,Production

Description

ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1

Uses

ML324 is a JMJD2 demethylase inhibitor. It blocks the initiation of viral lytic infection and HSV-1 reactivation in the sensory ganglia of latently infected mice.

References

1) Liang?et al. (2013),?Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med.,?5?167ra5

ML234 Preparation Products And Raw materials

Raw materials

Preparation Products

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ML234 Suppliers

Axon Medchem BV
Tel
--
Fax
--
Email
info@axonmedchem.com
Country
The Netherlands
ProdList
477
Advantage
30
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View Lastest Price from ML234 manufacturers

Career Henan Chemical Co
Product
ML234 1222800-79-4
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

1222800-79-4, ML234Related Search:


  • ML234
  • ML324
  • ML243
  • N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide
  • NCGC00183808-01
  • ML324(CID-44143209)
  • CS-2198
  • ML-324;ML324;ML 324
  • Benzamide, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-
  • ML234 USP/EP/BP
  • 5-Pyrroledione
  • ML324, ML-324
  • 1222800-79-4
  • Inhibitors