Uses Application
ChemicalBook > CAS DataBase List > 2-Amino-5-iodopyridine

2-Amino-5-iodopyridine

Uses Application
Product Name
2-Amino-5-iodopyridine
CAS No.
20511-12-0
Chemical Name
2-Amino-5-iodopyridine
Synonyms
AKOS BB-8250;ASISCHEM U79390;BUTTPARK 153\33-57;5-iodo-2-pyridinamin;5-IODOPYRIDIN-2-AMINE;5-IODO-2-PYRIDINAMINE;2-AMINO-5-IODOPYRIDINE;5-Iodopyridine-2-amine;5-Iodo-2-aminopyridine;2-Amiao-5-iodopyridine
CBNumber
CB7281679
Molecular Formula
C5H5IN2
Formula Weight
220.01
MOL File
20511-12-0.mol
More
Less

2-Amino-5-iodopyridine Property

Melting point:
128-131 °C (lit.)
Boiling point:
293.8±25.0 °C(Predicted)
Density 
2.055±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
4.91±0.13(Predicted)
form 
Solid
color 
Pale Yellow to Light Beige
Water Solubility 
Insoluble
Sensitive 
Light Sensitive
BRN 
108738
InChI
InChI=1S/C5H5IN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
InChIKey
IVILGUFRMDBUEQ-UHFFFAOYSA-N
SMILES
C1(N)=NC=C(I)C=C1
CAS DataBase Reference
20511-12-0(CAS DataBase Reference)
EPA Substance Registry System
2-Pyridinamine, 5-iodo- (20511-12-0)
More
Less

Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-20/21/22
Safety Statements 
26-36-37/39
WGK Germany 
3
Hazard Note 
Irritant
TSCA 
Yes
HS Code 
29333990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
516392
Product name
2-Amino-5-iodopyridine
Purity
98%
Packaging
1g
Price
$43.83
Updated
2025/07/31
TCI Chemical
Product number
A1842
Product name
2-Amino-5-iodopyridine
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
A1842
Product name
2-Amino-5-iodopyridine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$78
Updated
2025/07/31
TCI Chemical
Product number
A1842
Product name
2-Amino-5-iodopyridine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$234
Updated
2025/07/31
Usbiological
Product number
A1378-29
Product name
2-Amino-5-iodopyridine
Packaging
250mg
Price
$312
Updated
2021/12/16
More
Less

2-Amino-5-iodopyridine Chemical Properties,Usage,Production

Uses

2-Amino-5-iodopyridine is a compound that can be used in organic synthesis.

Application

2-Amino-5-iodopyridine, also known as 2-amino-5-iodopyridine or 5-iodo-2-aminopyridine, is an important intermediate in organic synthesis. It is mainly used as a pharmaceutical intermediate, and also in the production of dyes, pesticides, and fragrances.

Chemical Properties

Light yellow needles

Synthesis

504-29-0

20511-12-0

Example 20: Scheme C10 2-Aminopyridine (II) (1.0 eq, 318 mmol, 30.0 g), periodate dihydrate (0.15 eq, 48 mmol, 10.7 g), and iodine (0.42 eq, 134 mmol, 32.4 g) were dissolved in a mixture of acetic acid (800 mL), water (36 mL), and sulfuric acid (6.2 mL), and heated to react at 80°C for 4 for 4 hours. Upon completion of the reaction, the reaction mixture was poured into 10% Na2S2O3 aqueous solution to quench unreacted iodine and subsequently extracted with ether. The organic phases were combined, washed with 10% NaOH aqueous solution, dried over anhydrous MgSO4 and concentrated under reduced pressure. The crude product was purified by column chromatography (elution gradient: heptane/ethyl acetate 25:75 → pure ethyl acetate) to afford the target compound 2-amino-5-iodopyridine (116) (52.0 g, 74% yield). 1H NMR (δ, CDCl3): 4.51 (2H, s), 6.35 (1H, d, J = 8 Hz), 7.62 (1H, d, J = 8 Hz), 8.21 (1H, s).

References

[1] Journal of Heterocyclic Chemistry, 2017, vol. 54, # 5, p. 2656 - 2663
[2] European Journal of Medicinal Chemistry, 2010, vol. 45, # 3, p. 1211 - 1219
[3] Synthetic Communications, 2010, vol. 40, # 23, p. 3506 - 3513
[4] Synthetic Communications, 2013, vol. 43, # 21, p. 2913 - 2925
[5] Journal of the American Chemical Society, 2003, vol. 125, # 3, p. 616 - 617

2-Amino-5-iodopyridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

2-Amino-5-iodopyridine Suppliers

Americas 1 Austria 1 Belgium 1 Canada 1 China 398 Czech Republic 1 Europe 3 France 3 Germany 7 India 52 Japan 3 Jordan 1 Poland 1 Russia 1 Switzerland 3 Ukraine 1 United Kingdom 27 United States 57 Global 563
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
AbaChemScene
Tel
732-484-9848
Fax
888-484-5008
Email
sales@chemscene.com
Country
United States
ProdList
3982
Advantage
60
Accela ChemBio Inc.
Tel
+1-858-6993322
Fax
(+1)-858-876-1948
Email
info@accelachem.com
Country
United States
ProdList
21193
Advantage
58
Alchem Pharmtech,Inc.
Tel
8485655694
Email
sales@alchempharmtech.com
Country
United States
ProdList
63687
Advantage
58
Aladdin Scientific
Tel
Email
tp@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Aceschem Inc.
Tel
+1-817863-6948 +1-（817）863-6948
Email
sales@aceschem.com
Country
United States
ProdList
19632
Advantage
58
Anisyn, Inc.
Tel
--
Fax
--
Email
sales@anisyn.com
Country
United States
ProdList
863
Advantage
0
Chemphtec Corporation
Tel
--
Fax
--
Email
fo@chemphtec.com
Country
United States
ProdList
2181
Advantage
58
Redox Scientific
Tel
--
Fax
--
Email
info@redoxsci.com
Country
United States
ProdList
2380
Advantage
58
Alichem Inc.
Tel
--
Fax
--
Email
sales@alichem.com
Country
United States
ProdList
6167
Advantage
58
Tyger Scientific Inc.
Tel
--
Fax
--
Email
sales@tygersci.com
Country
United States
ProdList
402
Advantage
58
Apex Scientific Inc.
Tel
--
Fax
--
Email
apex_sci@att.net
Country
United States
ProdList
188
Advantage
0
Chiral Management
Tel
--
Fax
--
Email
sales@chiralmanagement.com
Country
United States
ProdList
1332
Advantage
30
OChem Incorporation
Tel
--
Fax
--
Email
sales@ocheminc.com
Country
United States
ProdList
6501
Advantage
60
Leonid Chemicals Private Limited
Tel
--
Fax
--
Email
careers@leonidchemicals.com
Country
United States
ProdList
1700
Advantage
43
Advanced Chemical Intermediates Ltd.
Tel
--
Fax
--
Email
enquiries@acints.com
Country
United States
ProdList
4893
Advantage
58
Heterocyclics Inc
Tel
--
Fax
--
Email
info@heterocyclics.com
Country
United States
ProdList
1669
Advantage
58
SynQuest Laboratories, Inc.
Tel
--
Fax
--
Email
info@synquestlabs.com
Country
United States
ProdList
6871
Advantage
62
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Aagile Labs Division of Tyger Scientific
Tel
--
Fax
--
Email
tygersci@yahoo.com
Country
United States
ProdList
6568
Advantage
68
Small Molecules, Inc.
Tel
--
Fax
--
Email
sales@small-molecules.com
Country
United States
ProdList
1218
Advantage
30
True Pharmachem Inc.
Tel
--
Fax
--
Email
sales@truepharmachem.com
Country
United States
ProdList
226
Advantage
60
Chemstock Inc.
Tel
--
Fax
--
Email
mail@chemstock.com
Country
United States
ProdList
575
Advantage
34
Small Molecules, Inc.
Tel
--
Fax
--
Email
sales@small-molecules.com
Country
United States
ProdList
990
Advantage
50
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6962
Advantage
56
Rintech, Inc.
Tel
--
Fax
--
Email
info@rintechinc.com
Country
United States
ProdList
3416
Advantage
60
AlliChem, LLC
Tel
--
Fax
--
Email
sales@allichemllc.com
Country
United States
ProdList
6516
Advantage
60
Combi-Blocks Inc.
Tel
--
Fax
--
Email
sales@combi-blocks.com
Country
United States
ProdList
6618
Advantage
69
Medical Isotopes
Tel
--
Fax
--
Email
stohler@medicalisotopes.com
Country
United States
ProdList
6181
Advantage
68
Ryan Scientific, Inc.
Tel
--
Fax
--
Email
ryan.reichlyn@ryansci.com
Country
United States
ProdList
6439
Advantage
60
NOVASYN ORGANICS PVT LTD
Tel
--
Fax
--
Email
info@novasynorganics.com
Country
United States
ProdList
1316
Advantage
55
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
Oakwood Products, Inc.
Tel
--
Fax
--
Email
sales@oakwoodchemical.com
Country
United States
ProdList
6193
Advantage
74
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
Adesis, Inc.
Tel
--
Fax
--
Email
info@adesisinc.com
Country
United States
ProdList
512
Advantage
64
2A PharmaChem USA
Tel
--
Fax
--
Email
sales@2apharmachem.com
Country
United States
ProdList
6137
Advantage
39
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
HONEST JOY HOLDINGS LIMITED
Tel
--
Fax
--
Email
sales@honestjoy.cn
Country
United States
ProdList
6675
Advantage
54
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
APAC Pharmaceutical, LLC
Tel
--
Fax
--
Email
sales@apacpharma.com
Country
United States
ProdList
6322
Advantage
38
Dishman Europe Ltd
Tel
--
Fax
--
Email
info@dishman-europe.com
Country
United States
ProdList
622
Advantage
58
Boron Molecular Inc.
Tel
--
Fax
--
Email
sales@boronmolecular-usa.com
Country
United States
ProdList
996
Advantage
65
Beta Pharma, Inc.
Tel
--
Fax
--
Email
sales@betapharma.com
Country
United States
ProdList
6226
Advantage
60
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
More
Less

View Lastest Price from 2-Amino-5-iodopyridine manufacturers

Shaanxi Dideu New Materials Co. Ltd
Product
2-Amino-5-iodopyridine 20511-12-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
10000KGS
Release date
2025-05-30
Henan Aochuang Chemical Co.,Ltd.
Product
2-Amino-5-iodopyridine 20511-12-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12
Henan Fengda Chemical Co., Ltd
Product
5-Iodo-2-pyridinamine 20511-12-0
Price
US $8.00-0.80/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-22

20511-12-0, 2-Amino-5-iodopyridineRelated Search:

4-Dimethylaminopyridine 2-Bromo-5-nitropyridine 2,6-Lutidine ALTRENOGEST 3-Aminophenol 6-Aminocaproic acid 3-Aminopyridine Glycine 2-Aminopyridine Tris(hydroxymethyl)aminomethane 4-AMINO-3-IODOPYRIDINE 2-AMINO-5-IODOPYRIDINE-3-CARBOXALDEHYDE 2-AMINO-5-IODOPYRIDINE-3-METHANOL 3-AMINO-4-IODOPYRIDINE 4-(Boc-amino)-3-iodopyridine, 96%,4-(Boc-amino)-3-iodopyridine 96% 4-AMINO-5-IODOPYRIDINE-3-CARBOXALDEHYDE 5-AMINO-2-IODOPYRIDINE 99%,5-AMINO-2-IODOPYRIDINE ETHYL N-(2-CYANO-3-[(5-IODO-2-PYRIDINYL)AMINO]ACRYLOYL)CARBAMATE

  • ASISCHEM U79390
  • BUTTPARK 153\33-57
  • 2-AMINO-5-IODOPYRIDINE
  • 2-PYRIDINAMINE, 5-IODO-
  • 5-IODOPYRIDIN-2-AMINE
  • 5-iodopyridin-2-amine(SALTDATA: FREE)
  • 2--5- aMinopyridine iodide
  • 5-iodo-2-pyridinylamine
  • 5-Iodo-2-aminopyridine
  • 2-Amino-5-iodopyridine ,98%
  • 5-Iodopyridine-2-amine
  • 2-Amiao-5-iodopyridine
  • 5-IODO-PYRIDIN-2-YLAMINE
  • 5-IODO-2-PYRIDINAMINE
  • AKOS BB-8250
  • 5-iodo-2-pyridinamin
  • 2-Amino-5-iodopyridine 97%
  • JR-6750, 5-Iodopyridin-2-amine, 97%
  • 2-Amino-5-iodopyridine&gt
  • 2-Amino-5-iodopyridine ISO 9001：2015 REACH
  • 2-Amino-5-Iodine Pyridine
  • 2-Amino-5-iodiodipyridine
  • 2-Amino-5-iodopyridine, 96%
  • 20511-12-0
  • 2051-12-0
  • C5H5IN
  • C5H5N2I
  • C5H5IN2
  • C5H6IN2
  • Pyridines
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Building Blocks
  • Halopyridines
  • Iodopyridines
  • Pyridines derivates
  • Heterocyclic Compounds
  • Anilines, Amides & Amines
  • Iodine Compounds
  • Miscellaneous Compounds
  • Halopyridines
  • Iodopyridines
  • Heterocycles
  • C5Heterocyclic Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridine
  • Amino-pyridine series
  • Amines
  • blocks
  • Iodides
  • Pyridines
  • Pyridine series
  • pyridine derivative
  • Pyridines, Pyrimidines, Purines and Pteredines