2-Amino-5-chloro-3-nitropyridine
- Product Name
- 2-Amino-5-chloro-3-nitropyridine
- CAS No.
- 5409-39-2
- Chemical Name
- 2-Amino-5-chloro-3-nitropyridine
- Synonyms
- TIMTEC-BB SBB003813;2-Amino-5-chloro-3-nitrpyridine;2-Amino-5-chloro Nitro Pyridine;2-Amino-5-chloro-3-nitropyridne;5-CHLORO-3-NITROPYRIDIN-2-AMINE;5-Chloro-3-nitro-[2]pyridylamine;2-AMINO-5-CHLORO-3-NITROPYRIDINE;5-Chloro-3-nitro-2-aminopyridine;2-PYRIDINAMINE, 5-CHLORO-3-NITRO-;2-Amino-3-nitro-5-chloro pyridine
- CBNumber
- CB7332544
- Molecular Formula
- C5H4ClN3O2
- Formula Weight
- 173.56
- MOL File
- 5409-39-2.mol
2-Amino-5-chloro-3-nitropyridine Property
- Melting point:
- 193-197 °C (lit.)
- Boiling point:
- 305.8±37.0 °C(Predicted)
- Density
- 1.596
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- soluble in Dimethylformamide
- form
- powder to crystal
- pka
- 0.17±0.49(Predicted)
- color
- Light yellow to Brown to Dark green
- BRN
- 383850
- CAS DataBase Reference
- 5409-39-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 594202
- Product name
- 2-Amino-5-chloro-3-nitropyridine
- Purity
- 97%
- Packaging
- 25g
- Price
- $150
- Updated
- 2023/06/20
- Product number
- A1557
- Product name
- 2-Amino-5-chloro-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- A1557
- Product name
- 2-Amino-5-chloro-3-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $117
- Updated
- 2025/07/31
- Product number
- A604208
- Product name
- 2-Amino-5-chloro-3-nitropyridine
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- A604208
- Product name
- 2-Amino-5-chloro-3-nitropyridine
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
2-Amino-5-chloro-3-nitropyridine Chemical Properties,Usage,Production
Chemical Properties
yellow crystalline powder
Uses
2-Amino-5-chloro-3-nitropyridine, a versatile building block, is widely used in food, health care products, cosmetics and other fields.
Synthesis
1072-98-6
5409-39-2
General procedure for the synthesis of 2-amino-3-nitro-5-chloropyridine from 2-amino-5-chloropyridine: 2-amino-5-chloropyridine (2.57 g, 20.0 mmol) was mixed with sulphuric acid (6.30 ml) at 25 °C, and nitric acid (0.860 ml, 21.1 mmol) was added slowly and dropwise over a period of 15 min. The reaction system was then warmed to 55°C with continuous stirring. After completion of the reaction, it was cooled to room temperature and the reaction mixture was slowly poured into ice water (60 g) and neutralized by adjusting the pH to 11 with aqueous sodium hydroxide solution. The precipitated solid product was collected by filtration, washed with deionized water and finally dried under reduced pressure at 50 °C to give 5-chloro-3-nitropyridin-2-amine (2.31 g, 67% yield, yellow solid).
References
[1] Synthetic Communications, 2012, vol. 42, # 19, p. 2791 - 2796
[2] Patent: WO2008/8398, 2008, A2. Location in patent: Page/Page column 369
[3] Bioorganic and Medicinal Chemistry, 2001, vol. 9, # 8, p. 2061 - 2071
[4] New Journal of Chemistry, 2015, vol. 39, # 5, p. 3936 - 3947
[5] Bioorganic and Medicinal Chemistry Letters, 1997, vol. 7, # 6, p. 669 - 674
2-Amino-5-chloro-3-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Amino-5-chloro-3-nitropyridine Suppliers
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- nfo@matrix-fine-chemicals.com
- Country
- Switzerland
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- 6968
- Advantage
- 58
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- Switzerland
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View Lastest Price from 2-Amino-5-chloro-3-nitropyridine manufacturers
- Product
- 2-Amino-5-chloro-3-nitropyridine 5409-39-2
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-08
- Product
- 2-Amino-5-chloro-3-nitropyridine 5409-39-2
- Price
- US $2.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100g , 1kg, 5kg , 50kg
- Release date
- 2020-01-07