(2-AMINO-PYRIDIN-4-YL)-METHANOL

Product Name: (2-AMINO-PYRIDIN-4-YL)-METHANOL
CAS No.: 105250-17-7
Chemical Name: (2-AMINO-PYRIDIN-4-YL)-METHANOL
Synonyms: 2-aMinopyridin-4-Methanol;2-AMINOPYRIDINE-4-METHANOL;2-AMINO-4-PYRIDINEMETHANOL;2-Amino-4-pyridinylmethanol;4-Pyridinemethanol, 2-amino-;2-Aminopyridine-4-methanol,97%;2-Amino-4-hydroxymethylpyridine;(2-AMINO-PYRIDIN-4-YL)-METHANOL;4-Pyridinemethanol,2-amino-(9CI);2-AMino-4-hyddroxyMethylpyridine
CBNumber: CB7349960
Molecular Formula: C6H8N2O
Formula Weight: 124.14
MOL File: 105250-17-7.mol

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(2-AMINO-PYRIDIN-4-YL)-METHANOL Property

Melting point:: 43-44°C
Boiling point:: 329.5±27.0 °C(Predicted)
Density: 1.257±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: 13.37±0.10(Predicted)
form: Crystalline Powder
color: White to yellow
Water Solubility: Soluble in water.
Sensitive: Air Sensitive
BRN: 8760550
InChI: InChI=1S/C6H8N2O/c7-6-3-5(4-9)1-2-8-6/h1-3,9H,4H2,(H2,7,8)
InChIKey: ZRJJXXDQIQFZBW-UHFFFAOYSA-N
SMILES: C1(N)=NC=CC(CO)=C1
CAS DataBase Reference: 105250-17-7(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 714577
Product name: 2-Amino-4-pyridinylmethanol
Purity: 97%
Packaging: 1g
Price: $54.28
Updated: 2025/07/31

TCI Chemical

Product number: A3249
Product name: 2-Amino-4-pyridinylmethanol
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $33
Updated: 2025/07/31

TCI Chemical

Product number: A3249
Product name: 2-Amino-4-pyridinylmethanol
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $129
Updated: 2025/07/31

TRC

Product number: A629063
Product name: (2-Aminopyridin-4-yl)methanol
Packaging: 100mg
Price: $75
Updated: 2021/12/16

ChemScene

Product number: CS-W003117
Product name: (2-Aminopyridin-4-yl)methanol
Purity: 99.44%
Packaging: 10g
Price: $79
Updated: 2021/12/16

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(2-AMINO-PYRIDIN-4-YL)-METHANOL Chemical Properties,Usage,Production

Chemical Properties

Light yellow Cryst

Uses

2-Aminopyridine-4-methanol is used as pharmaceutical intermediate.

Synthesis Reference(s)

Journal of Medicinal Chemistry, 44, p. 78, 2001 DOI: 10.1021/jm001034k

Synthesis

6937-03-7

105250-17-7

General procedure for the synthesis of 2-amino-4-pyridinemethanol from methyl 2-aminoisonicotinate: 26 g of lithium aluminum hydride was dissolved in 800 mL of anhydrous tetrahydrofuran (THF). Under stirring conditions, 103 g of 2-aminoisonicotinic acid methyl ester dissolved in 600 mL of anhydrous THF was slowly added, and the resulting slurry was heated to reflux for 3 hours. Upon completion of the reaction, the reaction was quenched by careful addition of cooling water, and the precipitate was collected by filtration and washed with 300 mL of THF. The filtrates were combined and concentrated under reduced pressure and the residue was recrystallized from benzene. The product was obtained as 61 g in 73% yield with a melting point of 80-81.5°C. The product was analyzed by 1H NMR (DMSO-d6, δ, ppm): 4.36 (s, 2H), 5.19 (s, 1H), 5.78 (s, 2H), 6.40 (d, 1H), 6.46 (s, 1H), 7.81 (d, 1H).13C NMR (DMSO- d6, δ, ppm): 62.3, 105.2, 110.3, 147.7, 152.7, 160.3. Elemental analysis results (%): C 57.63, H 6.32, N 22.68; theoretical values (C6H8N2O): C 58.05, H 6.40, N 22.56.

References

[1] Russian Journal of Organic Chemistry, 2015, vol. 51, # 5, p. 744 - 745
[2] Zh. Org. Khim., 2015, vol. 51, # 5, p. 759 - 760,2
[3] Patent: EP3018125, 2016, A1. Location in patent: Paragraph 0515-0516; 0519-0520
[4] Patent: US2003/100567, 2003, A1
[5] Patent: US2002/147203, 2002, A1

(2-AMINO-PYRIDIN-4-YL)-METHANOL Preparation Products And Raw materials

Raw materials

Acetic anhydride Acetone Triethylamine Lithium Aluminum Hydride Potassium permanganate Sodium hydroxide 4-Methylpyridin-2-amine

Preparation Products

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(2-AMINO-PYRIDIN-4-YL)-METHANOL Suppliers

Americas 1 China 173 Europe 2 France 1 Germany 6 India 4 Japan 1 Switzerland 1 The Netherlands 1 United Kingdom 5 United States 41 Global 236

ITIC MEDCHEM(SUZHOU) CO.,LTD.

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View Lastest Price from (2-AMINO-PYRIDIN-4-YL)-METHANOL manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: (2-AMINO-PYRIDIN-4-YL)-METHANOL 105250-17-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-04-30

Shaanxi Dideu Medichem Co. Ltd

Product: (2-AMINO-PYRIDIN-4-YL)-METHANOL 105250-17-7
Min. Order: 1KG
Purity: 99.0% min
Supply Ability: 100 tons
Release date: 2021-04-15

Career Henan Chemical Co

Product: 2-AMINO-PYRIDIN-4-YL)-METHANOL 105250-17-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: Judy@coreychem.com
Release date: 2019-12-18

105250-17-7, (2-AMINO-PYRIDIN-4-YL)-METHANOLRelated Search:

2-Aminoisonicotinic acid 4-(AMINOPYRIDINE-3-YL) METHANOL (2-AMINO-PYRIDIN-3-YL)-METHANOL,(2-Amino-pyridin-3-yl)-methanol ,97%,(2-AMINO-PYRIDIN-3-YL)-METHANOL (6-AMINO-PYRIDIN-3-YL)-METHANOL (3-AMINO-PYRIDIN-2-YL)-METHANOL Methyl 2-aminopyridine-4-carboxylate Ethyl 2-Aminoisonicotinate 2-MORPHOLIN-4-YL-ISONICOTINIC ACID 2-ACETYLAMINO-ISONICOTINIC ACID (3-AMINO-PYRIDIN-4-YL)-METHANOL 2-(2,2,2-TRIMETHYLACETAMIDO)PYRIDINE-3-METHANOL (4-AMINO-PYRIDIN-3-YL)-METHANOL 2-Aminopyridine (2-AMINO-PYRIDIN-4-YL)-METHANOL 2-(2,2-DIMETHYL-PROPIONYLAMINO)-ISONICOTINIC ACID METHYL ESTER 2-(Dimethylamino)-6-methyl-4-pyridinecarboxylicacid 2-(4-MORPHOLINYL)-PYRIDINE-4-CARBOXYLIC ACID METHYL ESTER 2-PIPERAZIN-1-YL-QUINOLINE-4-CARBOXYLIC ACID 4-Quinolinecarboxylic acid, 2-((2,4-dimethylphenyl)amino)-

2-AMINO-4-PYRIDINEMETHANOL

(2-AMINO-PYRIDIN-4-YL)-METHANOL

2-AMINOPYRIDINE-4-METHANOL

2-Amino-4-hydroxymethylpyridine

4-Pyridinemethanol,2-amino-(9CI)

2-Amino-4-pyridinylmethanol

(2-Amino-pyridin-4-yl)-methanol ,97%

(2-amino-4-pyridinyl)methanol(SALTDATA: FREE)

2-aMinopyridin-4-Methanol

4-(Hydroxymethyl)pyridin-2-amine, (2-Aminopyridin-4-yl)methanol

2-AMino-4-hyddroxyMethylpyridine

(2-AMinopyrid-4-yl)Methanol, 97%

2-Aminopyridine-4-methanol,97%

4-Pyridinemethanol, 2-amino-

(2-AMINO-PYRIDIN-4-YL)-METHANOL ISO 9001：2015 REACH

105250-17-7

PYRIDINE

pharmacetical

Pyridine series