ChemicalBook > CAS DataBase List > (R)-3-Hydroxypyrrolidine

(R)-3-Hydroxypyrrolidine

Product Name
(R)-3-Hydroxypyrrolidine
CAS No.
2799-21-5
Chemical Name
(R)-3-Hydroxypyrrolidine
Synonyms
(R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
CBNumber
CB7494161
Molecular Formula
C4H9NO
Formula Weight
87.12
MOL File
2799-21-5.mol
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(R)-3-Hydroxypyrrolidine Property

Melting point:
15°C
Boiling point:
215-216 °C (lit.)
alpha 
6.5 º (c=3.5% in MeOH)
Density 
1.078 g/mL at 20 °C (lit.)
refractive index 
n20/D 1.488(lit.)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
form 
Viscous Liquid
pka
14.91±0.20(Predicted)
Specific Gravity
1.048
color 
Clear yellow to orange-brown
optical activity
[α]20/D +6.5°, c = 3.5 in methanol
Water Solubility 
Soluble in water and methanol.
Sensitive 
Air Sensitive & Hygroscopic
BRN 
5376132
CAS DataBase Reference
2799-21-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39
WGK Germany 
3
F 
10-34
Hazard Note 
Irritant
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
382981
Product name
(R)-3-Pyrrolidinol
Purity
98%
Packaging
1g
Price
$85.4
Updated
2023/01/07
Sigma-Aldrich
Product number
382981
Product name
(R)-3-Pyrrolidinol
Purity
98%
Packaging
5g
Price
$137
Updated
2023/01/07
TCI Chemical
Product number
P1608
Product name
(R)-3-Pyrrolidinol
Purity
>98.0%(GC)
Packaging
1g
Price
$50
Updated
2024/03/01
TCI Chemical
Product number
P1608
Product name
(R)-3-Pyrrolidinol
Purity
>98.0%(GC)
Packaging
5g
Price
$151
Updated
2024/03/01
Alfa Aesar
Product number
L19499
Product name
(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
Packaging
1g
Price
$61.65
Updated
2024/03/01
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(R)-3-Hydroxypyrrolidine Chemical Properties,Usage,Production

Chemical Properties

clear yellow to orange-brown viscous liquid

Uses

(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.

Purification Methods

The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]

(R)-3-Hydroxypyrrolidine Preparation Products And Raw materials

Raw materials

Xylene iodine Benzylamine Sodium borohydride Palladium Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Dichloromethane Methanol D(+)-Malic acid

Preparation Products

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(R)-3-Hydroxypyrrolidine Suppliers

Americas 1 Belgium 2 Canada 2 China 205 Europe 1 France 1 Germany 6 India 6 Japan 12 South Korea 4 Switzerland 2 The Netherlands 1 United Kingdom 17 United States 48 Global 309
Alfa Aesar, Thermo Fisher Scientific
Tel
--
Fax
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Email
es@alfa.com
Country
Germany
ProdList
5123
Advantage
58
CHEMOS GmbH & Co. KG
Tel
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Fax
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Email
chemos@chemos.de
Country
Germany
ProdList
6727
Advantage
58
WeylChem GmbH
Tel
--
Fax
--
Country
Germany
ProdList
396
Advantage
64
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
PARAGOS
Tel
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Fax
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Email
info@paragos.com
Country
Germany
ProdList
6371
Advantage
39
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from (R)-3-Hydroxypyrrolidine manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
(R)-3-Hydroxypyrrolidine 2799-21-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-04
Zibo Hangyu Biotechnology Development Co., Ltd
Product
(R)-3-Hydroxypyrrolidine 2799-21-5
Price
US $80.00-800.00/kg
Min. Order
10kg
Purity
0.99
Supply Ability
20tons
Release date
2023-11-08
Henan Fengda Chemical Co., Ltd
Product
(R)-3-Hydroxypyrrolidine 2799-21-5
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08

2799-21-5, (R)-3-HydroxypyrrolidineRelated Search:

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  • (R)-3-PYRROLIDINOL
  • R-(-)-3-PYRROLIDINOL
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  • (R)-3-Hydroxypyrrolidine USP/EP/BP
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  • 2799-21-5
  • Asymmetric Synthesis
  • Simple Alcohols (Chiral)
  • Chiral Building Blocks
  • Heterocyclic Building Blocks
  • Pyrrolidines
  • pharmacetical
  • API intermediates
  • Chiral Building Blocks
  • Simple Alcohols (Chiral)
  • Synthetic Organic Chemistry