(R)-3-Hydroxypyrrolidine

Product Name: (R)-3-Hydroxypyrrolidine
CAS No.: 2799-21-5
Chemical Name: (R)-3-Hydroxypyrrolidine
Synonyms: (R)-PYRROLIDIN-3-OL;(3R)-Pyrrolidin-3-ol;R-HP;98%，ee99%;(R)-3-PYRROLIDINOL;(-)-3-Pyrrolidinol;(3R)-3-PYRROLIDINOL;3-PYRROLIDINOL, (R);(R)-Pyrrolidine-3-ol;R-(-)-3-PYRROLIDINOL
CBNumber: CB7494161
Molecular Formula: C4H9NO
Formula Weight: 87.12
MOL File: 2799-21-5.mol

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(R)-3-Hydroxypyrrolidine Property

Melting point:: 15°C
Boiling point:: 215-216 °C (lit.)
alpha: 6.5 º (c=3.5% in MeOH)
Density: 1.078 g/mL at 20 °C (lit.)
refractive index: n20/D 1.488(lit.)
Flash point:: >230 °F
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: Viscous Liquid
pka: 14.91±0.20(Predicted)
Specific Gravity: 1.048
color: Clear yellow to orange-brown
optical activity: [α]20/D +6.5°, c = 3.5 in methanol
Water Solubility: Soluble in water and methanol.
Sensitive: Air Sensitive & Hygroscopic
BRN: 5376132
CAS DataBase Reference: 2799-21-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39
WGK Germany: 3
F: 10-34
Hazard Note: Irritant
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 382981
Product name: (R)-3-Pyrrolidinol
Purity: 98%
Packaging: 1g
Price: $85.4
Updated: 2023/01/07

Sigma-Aldrich

Product number: 382981
Product name: (R)-3-Pyrrolidinol
Purity: 98%
Packaging: 5g
Price: $137
Updated: 2023/01/07

TCI Chemical

Product number: P1608
Product name: (R)-3-Pyrrolidinol
Purity: >98.0%(GC)
Packaging: 1g
Price: $50
Updated: 2024/03/01

TCI Chemical

Product number: P1608
Product name: (R)-3-Pyrrolidinol
Purity: >98.0%(GC)
Packaging: 5g
Price: $151
Updated: 2024/03/01

Alfa Aesar

Product number: L19499
Product name: (R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%
Packaging: 1g
Price: $61.65
Updated: 2024/03/01

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(R)-3-Hydroxypyrrolidine Chemical Properties,Usage,Production

Chemical Properties

clear yellow to orange-brown viscous liquid

Uses

(R)-Pyrrolidin-3-ol is used in preparation of allosteric BCR-ABL bifunctional proteolysis targeting chimera compounds.

Purification Methods

The (±)-isomer is purified by repeated distillation ( b 102-104o/12mm, 108-110o/18mm), and the (±)-picrate crystallises from EtOH with m 140-141o. The R(+)-enantiomer has b 70o/0.6mm and [] D +5.6o (c 3.63, MeOH). Its hydrochloride has a negative rotation and its dimethiodide has m 230o and [] 24 -8.02o. [Suyama & Kanno Yakugaku Zasshi (J Pharm Soc Japan) 85 531 1965, Uno et al. J Heterocycl Chem 24 1025 1987, Flanagan & Joullie Heterocycles 26 2247 1987, Beilstein 21 III/IV 44.]

(R)-3-Hydroxypyrrolidine Preparation Products And Raw materials

Raw materials

Xylene iodine Benzylamine Sodium borohydride Palladium Tetrahydrofuran Ethyl acetate Lithium Aluminum Hydride Dichloromethane Methanol D(+)-Malic acid

Preparation Products

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(R)-3-Hydroxypyrrolidine Suppliers

Americas 1 Belgium 2 Canada 2 China 204 Europe 1 France 1 Germany 6 India 6 Japan 12 South Korea 4 Switzerland 2 The Netherlands 1 United Kingdom 17 United States 48 Global 308

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
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Advantage: 80

ChemICHIBA (Namiki Shoji Co., Ltd.)

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Sanyo Fine Co., Ltd.

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Toray Fine Chemicals Co., Ltd. (TFC)

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Fine Corporation

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K. Sakai & Co., Ltd.

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TCI Japan

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FUJIFILM Wako Pure Chemical Corporation

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DAISO CO., LTD.

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Wako Pure Chemical Industries, Ltd.

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Toray Fine Chemicals Co., Ltd.

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Kanto Chemical Co., Inc.

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ProdList: 6756
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View Lastest Price from (R)-3-Hydroxypyrrolidine manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: (R)-3-Hydroxypyrrolidine 2799-21-5
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

Zibo Hangyu Biotechnology Development Co., Ltd

Product: (R)-3-Hydroxypyrrolidine 2799-21-5
Price: US $80.00-800.00/kg
Min. Order: 10kg
Purity: 0.99
Supply Ability: 20tons
Release date: 2023-11-08

Henan Fengda Chemical Co., Ltd

Product: (R)-3-Hydroxypyrrolidine 2799-21-5
Price: US $34.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-04-08

2799-21-5, (R)-3-HydroxypyrrolidineRelated Search:

N-Vinyl-2-pyrrolidone N-Methyl-2-pyrrolidone Polyvinylpyrrolidone 3-Pyrrolidinol Povidone iodine Pyrrolidine SCOPOLAMINE N-OXIDE HYDROBROMIDE METHYL-2-PYRROLIDONE Boc-Hyp-OH (2S,4R)-1-Acetyl-4-hydroxypyrrolidine-2-carboxylic acid RETRORSINE BOC-HYP(BZL)-OH CYTOCHALASIN A N-Cbz-Hydroxy-L-proline SWAINSONINE cis-4-Hydroxy-D-proline DIHYDROCYTOCHALASIN B CYTOCHALASIN E

(3R)-3-PYRROLIDINOL

(3R)-Pyrrolidin-3-ol

R-(+)-3-PYRROLIDINOL 98%

(R)-(+)-3-HYDROXYPYRROLIDINE , EE 99%

(R)-(+)-3-Hydroxypyrrolidine, 99%, ee 99%

(3R)-Pyrrolidine-3-ol

(R)-Pyrrolidine-3-ol

(R)-(+)-3-Pyrrolidinol,98%

(R)-Hydroxypyrrolidine

(R)-(+)-3-Pyrrolidiol

(3R)-3-Hydroxypyrrolidine

(R)-(+)-3-Pyrrolidinol, 98% 1GR

(R)-(+)-3-Pyrrolidinol, 98% 5GR

(R)-3-Hydroxypyrrolidine ,98%

(R)-pyrrolidin-3-ol (hydrobroMide)

3-Pyrrolidinol, (3R)-

(R)-3-Hydroxypyrrolidine ((R)-3-Pyrrolidinol)

98%，ee99%

(R) - four hydroxyl hydrogen pyrrole

(R)-(+)-3-Hydroxypyrrolidine,99%,ee99%

R-HP

(R)-(+)-3-PYRROLIDINOL

(R)-3-PYRROLIDINOL

R-(-)-3-PYRROLIDINOL

(R)-(+)-3-HYDROXYPYRROLIDINE

(R)-3-HYDROXYPYRROLIDINE

(R)-PYRROLIDIN-3-OL

(R)-3-Pyrrolidinol,99%e.e.

3-PYRROLIDINOL, (R)

(R)-3-Pyrrolidinol&gt

(R)-3-Hydroxypyrrolidine USP/EP/BP

(-)-3-Pyrrolidinol

2799-21-5

Asymmetric Synthesis

Simple Alcohols (Chiral)

Chiral Building Blocks

Heterocyclic Building Blocks

Pyrrolidines

pharmacetical

API intermediates

Chiral Building Blocks

Simple Alcohols (Chiral)

Synthetic Organic Chemistry