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TAXIFOLIN 3-O-RHAMNOSIDE

Product Name
TAXIFOLIN 3-O-RHAMNOSIDE
CAS No.
29838-67-3
Chemical Name
TAXIFOLIN 3-O-RHAMNOSIDE
Synonyms
Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin, 98%, from Smilax glabra Roxb.;Astilbin froM Engelhardtia roxburghiana
CBNumber
CB7507018
Molecular Formula
C21H22O11
Formula Weight
450.4
MOL File
29838-67-3.mol
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TAXIFOLIN 3-O-RHAMNOSIDE Property

Melting point:
180 °C (decomp)
Boiling point:
801.1±65.0 °C(Predicted)
Density 
1.74
storage temp. 
Sealed in dry,2-8°C
solubility 
H2O: soluble1mg/mL, clear, colorless
pka
7.34±0.60(Predicted)
form 
A crystalline solid
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Safety

Hazard Codes 
N
Risk Statements 
50
Safety Statements 
61
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
A2862
Product name
Astilbin from Engelhardtia roxburghiana
Purity
≥98%
Packaging
10mg
Price
$199
Updated
2024/03/01
Cayman Chemical
Product number
28267
Product name
Astilbin
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
28267
Product name
Astilbin
Packaging
100mg
Price
$537
Updated
2024/03/01
Cayman Chemical
Product number
28267
Product name
Astilbin
Packaging
5mg
Price
$62
Updated
2024/03/01
Cayman Chemical
Product number
28267
Product name
Astilbin
Packaging
25mg
Price
$239
Updated
2024/03/01
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TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Usage,Production

Description

Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.

Definition

ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.

TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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TAXIFOLIN 3-O-RHAMNOSIDE Suppliers

China 205 Germany 1 India 2 South Korea 1 United Kingdom 1 United States 16 Global 226
Chembest Research Laboratories Limited
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021-20908456
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021-58180499
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sales@BioChemBest.com
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China
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61
Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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zhangsn@titansci.com
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China
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Nanjing Chemlin Chemical Co., Ltd
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025-83697070
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+86-25-83453306
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info@chemlin.com.cn
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China
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18086
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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China
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BEST-REAGENT
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028-84555506 800101999
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Sinopharm Chemical Reagent Co,Ltd.
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86-21-63210123
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86-21-63290778 86-21-63218885
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sj_scrc@sinopharm.com
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China
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Aktin Chemicals, Inc.
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86-28-85159085
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86-28-85152372
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Shenzhen Sungening Bio-Tech Co., Ltd
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+86-0755-89668383
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+86-0755-89594066/4038
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sales@sungening.com
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China
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BOC Sciences
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1-631-485-4226; 16314854226
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info@bocsci.com
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United States
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Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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sales@meilune.com
Country
China
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4668
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View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers

Hebei Kingfiner Technology Development Co.Ltd
Product
TAXIFOLIN 3-O-RHAMNOSIDE 29838-67-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
50000kg
Release date
2024-05-17
Changsha Staherb Natural Ingredients Co., Ltd.
Product
TAXIFOLIN 3-O-RHAMNOSIDE 29838-67-3
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
≥98% HPLC
Supply Ability
1000kg
Release date
2022-10-12
Hebei Guanlang Biotechnology Co,.LTD
Product
Astilbin 29838-67-3
Price
US $10.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2021-07-09

29838-67-3, TAXIFOLIN 3-O-RHAMNOSIDERelated Search:

Swertiamarine Deacetyltaxol 7-EPI-10-DEACETYLTAXOL Cryptotanshinone Mogroside V PROCYANIDIN B2 Dioscin 7-Xylosyl-10-deacetyltaxol 7-Epitaxol Cephalomannine Forskolin SCUTELLAREIN CASTICIN Hydroxysafflor yellow A TAXIFOLIN 3-O-RHAMNOSIDE PINOBANKSIN DIHYDROKAEMPFEROL (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one

  • Taxifolin 3-o-rhamnoside
  • Astilbin
  • Astilbin Taxifolin 3-O-rhaMnoside
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside
  • Taxifolin 3-rhaMnoside
  • Astilbin froM Engelhardtia roxburghiana
  • Dihydroquercetin 3-rhamnoside
  • Astilbin, 98%, from Smilax glabra Roxb.
  • (2R,3R)-3-[(6-Deoxy-alpha-L-mannopyranosyloxy)]-2-(3,4-dihydroxy-phenyl)-2,3-dihydro-5,7-dihydroxy-4H-chromen-4-one
  • (2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one
  • 4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3R)-
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one
  • (2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chroman-4-one
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihy...
  • Astilbin (6CI, 7CI, 8CI)
  • Loastilin
  • 29838-67-3
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract