TAXIFOLIN 3-O-RHAMNOSIDE
- Product Name
- TAXIFOLIN 3-O-RHAMNOSIDE
- CAS No.
- 29838-67-3
- Chemical Name
- TAXIFOLIN 3-O-RHAMNOSIDE
- Synonyms
- Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Astilbin-RM;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin, 98%, from Smilax glabra Roxb.
- CBNumber
- CB7507018
- Molecular Formula
- C21H22O11
- Formula Weight
- 450.4
- MOL File
- 29838-67-3.mol
TAXIFOLIN 3-O-RHAMNOSIDE Property
- Melting point:
- 180 °C (decomp)
- Boiling point:
- 801.1±65.0 °C(Predicted)
- Density
- 1.74
- storage temp.
- Sealed in dry,2-8°C
- solubility
- H2O: soluble1mg/mL, clear, colorless
- pka
- 7.34±0.60(Predicted)
- form
- A crystalline solid
- color
- White to off-white
- InChIKey
- ZROGCCBNZBKLEL-MQGABXIONA-N
- SMILES
- O([C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@H]1C(C2=C(C=C(O)C=C2O[C@@H]1C1C=CC(O)=C(O)C=1)O)=O |&1:1,4,6,8,10,12,22,r|
N-Bromosuccinimide Price
- Product number
- A2862
- Product name
- Astilbin from Engelhardtia roxburghiana
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $199
- Updated
- 2024/03/01
- Product number
- 28267
- Product name
- Astilbin
- Packaging
- 10mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 28267
- Product name
- Astilbin
- Packaging
- 100mg
- Price
- $537
- Updated
- 2024/03/01
- Product number
- 28267
- Product name
- Astilbin
- Packaging
- 5mg
- Price
- $62
- Updated
- 2024/03/01
- Product number
- 28267
- Product name
- Astilbin
- Packaging
- 25mg
- Price
- $239
- Updated
- 2024/03/01
TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Usage,Production
Description
Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC50s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.
Uses
Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.
Definition
ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.
TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials
Raw materials
Preparation Products
TAXIFOLIN 3-O-RHAMNOSIDE Suppliers
- Tel
- --
- Fax
- --
- Country
- Germany
- ProdList
- 1136
- Advantage
- 62
View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers
- Product
- TAXIFOLIN 3-O-RHAMNOSIDE 29838-67-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- ≥98% HPLC
- Supply Ability
- 1000kg
- Release date
- 2022-10-12
- Product
- Astilbin 29838-67-3
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 80%HPLC
- Supply Ability
- 1 ton
- Release date
- 2024-11-11
- Product
- Astilbin 29838-67-3
- Price
- US $10.50/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 ton
- Release date
- 2024-08-21