TAXIFOLIN 3-O-RHAMNOSIDE

ChemicalBook > CAS DataBase List > TAXIFOLIN 3-O-RHAMNOSIDE

TAXIFOLIN 3-O-RHAMNOSIDE

Product Name: TAXIFOLIN 3-O-RHAMNOSIDE
CAS No.: 29838-67-3
Chemical Name: TAXIFOLIN 3-O-RHAMNOSIDE
Synonyms: Astilbin;(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside;Loastilin;Astilbin-RM;Taxifolin 3-rhaMnoside;Taxifolin 3-o-rhamnoside;Astilbin (6CI, 7CI, 8CI);Dihydroquercetin 3-rhamnoside;Astilbin Taxifolin 3-O-rhaMnoside;Astilbin, 98%, from Smilax glabra Roxb.
CBNumber: CB7507018
Molecular Formula: C21H22O11
Formula Weight: 450.4
MOL File: 29838-67-3.mol

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TAXIFOLIN 3-O-RHAMNOSIDE Property

Melting point:: 180 °C (decomp)
Boiling point:: 801.1±65.0 °C(Predicted)
Density: 1.74
storage temp.: Sealed in dry,2-8°C
solubility: H2O: soluble1mg/mL, clear, colorless
pka: 7.34±0.60(Predicted)
form: A crystalline solid
color: White to off-white
InChIKey: ZROGCCBNZBKLEL-MQGABXIONA-N
SMILES: O([C@]1([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@H]1C(C2=C(C=C(O)C=C2O[C@@H]1C1C=CC(O)=C(O)C=1)O)=O |&1:1,4,6,8,10,12,22,r|

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Safety

Hazard Codes: N
Risk Statements: 50
Safety Statements: 61
RIDADR: UN 3077 9 / PGIII
WGK Germany: 3
HS Code: 29389090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H400Very toxic to aquatic life
Precautionary statements: P273Avoid release to the environment.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: A2862
Product name: Astilbin from Engelhardtia roxburghiana
Purity: ≥98%
Packaging: 10mg
Price: $199
Updated: 2024/03/01

Cayman Chemical

Product number: 28267
Product name: Astilbin
Packaging: 10mg
Price: $109
Updated: 2024/03/01

Cayman Chemical

Product number: 28267
Product name: Astilbin
Packaging: 100mg
Price: $537
Updated: 2024/03/01

Cayman Chemical

Product number: 28267
Product name: Astilbin
Packaging: 5mg
Price: $62
Updated: 2024/03/01

Cayman Chemical

Product number: 28267
Product name: Astilbin
Packaging: 25mg
Price: $239
Updated: 2024/03/01

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TAXIFOLIN 3-O-RHAMNOSIDE Chemical Properties,Usage,Production

Description

Astilbin is a flavonoid that has been found in S. glabra and has diverse biological activities. It inhibits cisplatin-induced increases in apoptosis and accumulation of reactive oxygen species (ROS) in HEK293 cells when used at a concentration of 200 μM. Astilbin (50 mg/kg) increases renal glutathione (GSH) levels and superoxide dismutase (SOD) and catalase activity and reduces serum creatinine and blood urea nitrogen (BUN) levels, renal IL-1β, IL-6, and TNF-α levels, apoptosis in kidney tissue, and kidney injury in a mouse model of cisplatin-induced nephrotoxicity. It reduces loss of dopaminergic neurons in the substantia nigra and increases striatal GSH levels and SOD activity in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 50 mg/kg per day. Astilbin also reduces descent time in a pole test and increases traction test score in a mouse model of Parkinson''s disease, indicating reduced motor deficits. It reduces cell viability of MDA-MB-231 and MCF-7 cells (IC₅₀s = 167.9 and 191.6 μM, respectively), as well as inhibits migration and increases apoptosis when used at concentrations of 50 and 200 μM. Astilbin (20 mg/kg every other day for 14 days) reduces tumor growth in an MCF-7 mouse xenograft model.

Uses

Astilbin displays anti-depressant activity involving monoaminergic neurotransmitters an the BDNF signal pathway. Anti-oxidant.

Definition

ChEBI: A flavanone glycoside that is (+)-taxifolin substituted by a alpha-L-rhamnosyl moiety at position 3 via a glycosidic linkage.

TAXIFOLIN 3-O-RHAMNOSIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from TAXIFOLIN 3-O-RHAMNOSIDE manufacturers

Changsha Staherb Natural Ingredients Co., Ltd.

Product: TAXIFOLIN 3-O-RHAMNOSIDE 29838-67-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98% HPLC
Supply Ability: 1000kg
Release date: 2022-10-12

Hovane Phytochemicals Co., Ltd

Product: Astilbin 29838-67-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 80%HPLC
Supply Ability: 1 ton
Release date: 2024-11-11

Hebei Chuanghai Biotechnology Co,.LTD

Product: Astilbin 29838-67-3
Price: US $10.50/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 ton
Release date: 2024-08-21

29838-67-3, TAXIFOLIN 3-O-RHAMNOSIDERelated Search:

Swertiamarine Deacetyltaxol 7-EPI-10-DEACETYLTAXOL Cryptotanshinone Mogroside V PROCYANIDIN B2 Dioscin 7-Xylosyl-10-deacetyltaxol 7-Epitaxol Cephalomannine Forskolin SCUTELLAREIN CASTICIN Hydroxysafflor yellow A TAXIFOLIN 3-O-RHAMNOSIDE PINOBANKSIN DIHYDROKAEMPFEROL (2R,3R)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one

Taxifolin 3-o-rhamnoside

Astilbin

Astilbin Taxifolin 3-O-rhaMnoside

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihydro-2H-chroMen-3-yl 6-deoxy-alpha-L-Mannopyranoside

Taxifolin 3-rhaMnoside

Astilbin froM Engelhardtia roxburghiana

Dihydroquercetin 3-rhamnoside

Astilbin, 98%, from Smilax glabra Roxb.

(2R,3R)-3-[(6-Deoxy-alpha-L-mannopyranosyloxy)]-2-(3,4-dihydroxy-phenyl)-2,3-dihydro-5,7-dihydroxy-4H-chromen-4-one

(2S,3S)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-oxan-2-yl]oxy-chroman-4-one

4H-1-Benzopyran-4-one, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-, (2R,3R)-

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-2,3-dihydrochromen-4-one

(2R,3R)-2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)chroman-4-one

(2R,3R)-2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-3,4-dihy...

Astilbin (6CI, 7CI, 8CI)

Loastilin

Astilbin-RM

29838-67-3

Inhibitors

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract