ChemicalBook > CAS DataBase List > 1-BENZHYDRYLPIPERAZINE

1-BENZHYDRYLPIPERAZINE

Product Name
1-BENZHYDRYLPIPERAZINE
CAS No.
841-77-0
Chemical Name
1-BENZHYDRYLPIPERAZINE
Synonyms
Diphenylmethylpiperazine;1-(DIPHENYLMETHYL)PIPERAZINE;NSC 35536;norcyclizine;AKOS NCG1-0108;AKOS BBS-00003601;TIMTEC-BB SBB003136;BENZHYDRYLPIPERAZINE;Benzhydrol piperzine;1-BENZHYDRYLPIPERAZINE
CBNumber
CB8117067
Molecular Formula
C17H20N2
Formula Weight
252.35
MOL File
841-77-0.mol
More
Less

1-BENZHYDRYLPIPERAZINE Property

Melting point:
90-93 °C
Boiling point:
185°C/2mmHg(lit.)
Density 
1.0546 (rough estimate)
vapor pressure 
0.001Pa at 20℃
refractive index 
1.5794 (estimate)
Flash point:
115 °C
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Methanol (Slightly)
pka
9.05±0.10(Predicted)
form 
Crystalline Powder
color 
White to light yellow
Water Solubility 
0.45 g/L (20 ºC)
Sensitive 
Air Sensitive
BRN 
222773
LogP
0.6 at 20℃
CAS DataBase Reference
841-77-0(CAS DataBase Reference)
NIST Chemistry Reference
Benzhydryl piperazine(841-77-0)
More
Less

Safety

Hazard Codes 
Xn,Xi
Risk Statements 
22
Safety Statements 
22-24/25
WGK Germany 
3
RTECS 
TL6465000
F 
34
HazardClass 
IRRITANT
HS Code 
29339900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B3760
Product name
1-Benzhydrylpiperazine
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$84
Updated
2024/03/01
TCI Chemical
Product number
B3760
Product name
1-Benzhydrylpiperazine
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$251
Updated
2024/03/01
Alfa Aesar
Product number
L11530
Product name
1-Benzhydrylpiperazine, 97%
Packaging
25g
Price
$39.7
Updated
2024/03/01
Alfa Aesar
Product number
L11530
Product name
1-Benzhydrylpiperazine, 97%
Packaging
100g
Price
$85.6
Updated
2024/03/01
TRC
Product number
B196950
Product name
1-Benzhydrylpiperazine
Packaging
50g
Price
$95
Updated
2021/12/16
More
Less

1-BENZHYDRYLPIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystalline powder

Uses

Cinnarizine (C465300) impurity.

Uses

1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.

Uses

1-Benzhydrylpiperazine is an intermediate used in drug synthesis

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 1098, 1955 DOI: 10.1021/ja01610a006

General Description

1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes. It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones.

Flammability and Explosibility

Not classified

1-BENZHYDRYLPIPERAZINE Preparation Products And Raw materials

Raw materials

Piperazine Dilute hydrochloric acid Benzhydrol Chlorodiphenylmethane

Preparation Products

Meclozine Oxatomide Stugeron
More
Less

1-BENZHYDRYLPIPERAZINE Suppliers

Americas 1 Belgium 1 Canada 1 China 185 Europe 5 France 1 Germany 9 India 79 Japan 6 Russia 2 Slovakia 1 South Korea 1 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 14 United States 52 Global 365
Yangzhou Aoxin Chemical Co., Ltd
Tel
0514-87754778 13901446058
Fax
+86-514-87752291
Email
sales@aochem.com
Country
China
ProdList
73
Advantage
66
Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
Tel
0513-82104991 18912868322
Fax
QQ1907456386
Email
sales10@btcpharm.com
Country
China
ProdList
1361
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006608290; 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40241
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30132
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18217
Advantage
66
Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel
+86-21-54098501
Fax
+86-21-54096319
Email
sales@sinch.com.cn
Country
China
ProdList
11605
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9816
Advantage
59
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32344
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
0712-0712-2580635 15527768850
Email
1791901229@qq.com
Country
China
ProdList
8849
Advantage
52
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
China Langchem Inc.
Tel
0086-21-58956006
Fax
0086-21-58956100
Country
China
ProdList
7815
Advantage
57
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400 638 7771
Email
sales@heowns.com
Country
China
ProdList
14443
Advantage
57
Aemon Chemical
Tel
0086-755-86198205
Email
acinfo@aemonchem.com
Country
China
ProdList
1937
Advantage
57
Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
11714
Advantage
57
Spectrum Chemical Manufacturing Corp.
Tel
021-021-021-67601398-809-809-809 15221380277
Fax
021-57711696
Email
marketing_china@spectrumchemical.com
Country
China
ProdList
9664
Advantage
60
Suzhou Guide Fine Material Co.Ltd.
Tel
136-16210669 13914021065
Fax
0512-66627360
Email
sales@guide-chemicals.com
Country
China
ProdList
294
Advantage
60
BioBioPha Co., Ltd.
Tel
0871-65217109 13211707573;
Fax
0871-65215563
Email
y.liu@mail.biobiopha.com
Country
China
ProdList
5654
Advantage
65
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-4000505016 13380397412
Fax
0755 28094224
Email
3001272453@qq.com
Country
China
ProdList
4974
Advantage
50
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17779
Advantage
75
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6181
Advantage
58
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18216
Advantage
56
Simagchem Corp.
Tel
86 592 2680277
Fax
0086 592 2680237
Email
sale@simagchem.com
Country
China
ProdList
430
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
18521735133 18521732826;
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25015
Advantage
65
Quzhou Juhua Friendship Co., Ltd
Tel
0570-3066667
Fax
0570-3063388
Country
China
ProdList
3933
Advantage
58
Shanghai Hao Yun Chemical Science Co.,Ltd.
Tel
021-68367562 15002147577;
Fax
021-68369562
Email
sales@haoyunchem.com
Country
China
ProdList
462
Advantage
55
ChemStrong Scientific Co.,Ltd
Tel
0755-0755-66853366 13670046396
Fax
0755-28363542
Email
sales@chem-strong.com
Country
China
ProdList
17982
Advantage
56
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9636
Advantage
58
Credit-Chem Co., Ltd.
Tel
400-821-5857 021-64326257
Fax
021-64393586 QQ;2798200800
Email
credit-chem@foxmail.com
Country
China
ProdList
5223
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4951
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10287
Advantage
55
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Shanghai Kewel Chemical Co., Ltd.
Tel
021-64609169 18901607656
Fax
021-64609160
Email
greensnown@163.com
Country
China
ProdList
9911
Advantage
50
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
982
Advantage
55
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Shanghai Song Yuan Chemical Technology Co., Ltd.
Tel
010-1234567 18521000990
Fax
86-021-33275113
Email
sonyuanchemical@163.com
Country
China
ProdList
6490
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Chizhou Kailong Import and Export Trade Co., Ltd.
Tel
Fax
-
Email
xg01_gj@163.com
Country
China
ProdList
9503
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51471
Advantage
80
Nanjing XiZe Biotechnology CO., Ltd.
Tel
025-58362220 15250997978
Fax
025-58362220
Email
1511893459@qq.com
Country
China
ProdList
7715
Advantage
55
Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
3991
Advantage
60
Zhengzhou Alfachem Co., Ltd.
Tel
0371-53765687 18937137882
Fax
QQ:2885373884
Email
2853979813@qq.com
Country
China
ProdList
7998
Advantage
55
Chengdu RunZeBenTu Chemical Co., Ltd
Tel
028-88469284 18000562381
Email
rzbtsj@163.com
Country
China
ProdList
9958
Advantage
56
ShangHai Siyan Biological Technology Co., Ltd.
Tel
021-50908862，442785678，326799392 18721037013
Fax
021-50908862
Email
siyansales@126.com
Country
China
ProdList
9638
Advantage
58
Shanghai Qiao Chemical Science Co., Ltd
Tel
021-58892003
Email
info@qiaochem.com
Country
China
ProdList
5881
Advantage
65
More
Less

View Lastest Price from 1-BENZHYDRYLPIPERAZINE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
1-Benzhydrylpiperazine 841-77-0
Price
US $0.00/KG
Min. Order
1KG
Purity
98%min
Supply Ability
30tons/month
Release date
2023-02-03
Dideu Industries Group Limited
Product
1-BENZHYDRYLPIPERAZINE 841-77-0
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons
Release date
2022-02-18
Shaanxi Dideu Medichem Co. Ltd
Product
1-BENZHYDRYLPIPERAZINE 841-77-0
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-27

841-77-0, 1-BENZHYDRYLPIPERAZINERelated Search:

1-(DiphenylMethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl)-3-buten-1-yl]piperazine IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine IMp. C (EP): (4-(DiphenylMethyl)-1,1-bis[(E)-3-phenylprop-2-enyl]piperaziniuM Chloride (Z)-Cinnarizine Chlorodiphenylphosphine CHLORCYCLIZINE Cyclizine 1-BENZHYDRYLPIPERAZINE Hydroxyzine dihydrochloride CHLORCYCLIZINE HYDROCHLORIDE Flunarizine dihydrochloride Meclizine dihydrochloride 4,4'-Difluorobenzhydrylpiperazine 1-(4-Chlorobenzhydryl)piperazine Stugeron 1-(4,4'-DICHLOROBENZHYDRYL)PIPERAZINE Buterizine Piperazine

  • 1-(diphenylmethyl)-piperazin
  • 1-(Diphenylmethyl)piperazine,97%
  • AKOS BBS-00003601
  • AKOS NCG1-0108
  • TIMTEC-BB SBB003136
  • N-BENZHYDRYLPIPERAZINE
  • N-BENZYLHYDRYLPIPERAZINE
  • 1-(DIPHENYLMETHYL)PIPERAZINE
  • 1-BENZHYDRYLPIPERAZINE
  • 1-BENZYHYDRYLPIPERAZINE
  • BENZHYDRYLPIPERAZINE
  • LABOTEST-BB LT00454383
  • 1-Benzhydrylpiperazine 97%
  • 1-Benzhydrylpiperazine ,99%
  • Cinnarizine Impurity 1(Cinnarizine EP Impurity A)
  • Piperazine, 1-(diphenylmethyl)-
  • 4-(DiphenylMethyl)piperazine
  • NSC 35536
  • Cinnarizine EP IMpurity A
  • 1-(DiphenylMethyl)piperazine SynonyMs Benzhydrylpiperazine
  • 1-(Diphenylmethyl)piperazine >=98.0% (NT)
  • 1-(Diphenylmethyl)piperazineone
  • 4-benzhydrylpiperazine
  • Diphenylmethylpiperazine
  • N-(Diphenylmethyl)piperazine
  • norcyclizine
  • Cetirizine SM impurity 1 HCl
  • 1-Benzhydrylpiperazine &gt
  • 1-BENZHYDRYLPIPERAZINE ISO 9001：2015 REACH
  • Cinnarizine EP Impurity A 841-77-0
  • Nor-cyclizineQ: What is Nor-cyclizine Q: What is the CAS Number of Nor-cyclizine Q: What is the storage condition of Nor-cyclizine Q: What are the applications of Nor-cyclizine
  • 1-BENZHYDRYLPIPERAZINEidazol-2-one
  • Benzhydrol piperzine
  • 841-77-0
  • C20H17N2
  • C17H20N2
  • AMINE
  • Building Blocks
  • Piperazines
  • Heterocyclic Building Blocks
  • Building Blocks
  • C16 to C29
  • Chemical Synthesis
  • Heterocyclic Building Blocks
  • Piperazines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Piperaizine
  • Piperazine derivates
  • Aromatics