1-BENZHYDRYLPIPERAZINE

Product Name: 1-BENZHYDRYLPIPERAZINE
CAS No.: 841-77-0
Chemical Name: 1-BENZHYDRYLPIPERAZINE
Synonyms: Diphenylmethylpiperazine;1-(DIPHENYLMETHYL)PIPERAZINE;NSC 35536;norcyclizine;AKOS NCG1-0108;AKOS BBS-00003601;TIMTEC-BB SBB003136;BENZHYDRYLPIPERAZINE;Benzhydrol piperzine;1-BENZHYDRYLPIPERAZINE
CBNumber: CB8117067
Molecular Formula: C17H20N2
Formula Weight: 252.35
MOL File: 841-77-0.mol

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1-BENZHYDRYLPIPERAZINE Property

Melting point:: 90-93 °C
Boiling point:: 185°C/2mmHg(lit.)
Density: 1.0546 (rough estimate)
vapor pressure: 0.001Pa at 20℃
refractive index: 1.5794 (estimate)
Flash point:: 115 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Methanol (Slightly)
pka: 9.05±0.10(Predicted)
form: Crystalline Powder
color: White to light yellow
Water Solubility: 0.45 g/L (20 ºC)
Sensitive: Air Sensitive
BRN: 222773
LogP: 0.6 at 20℃
CAS DataBase Reference: 841-77-0(CAS DataBase Reference)
NIST Chemistry Reference: Benzhydryl piperazine(841-77-0)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22
Safety Statements: 22-24/25
WGK Germany: 3
RTECS: TL6465000
F: 34
HazardClass: IRRITANT
HS Code: 29339900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3760
Product name: 1-Benzhydrylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $84
Updated: 2024/03/01

TCI Chemical

Product number: B3760
Product name: 1-Benzhydrylpiperazine
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $251
Updated: 2024/03/01

Alfa Aesar

Product number: L11530
Product name: 1-Benzhydrylpiperazine, 97%
Packaging: 25g
Price: $39.7
Updated: 2024/03/01

Alfa Aesar

Product number: L11530
Product name: 1-Benzhydrylpiperazine, 97%
Packaging: 100g
Price: $85.6
Updated: 2024/03/01

TRC

Product number: B196950
Product name: 1-Benzhydrylpiperazine
Packaging: 50g
Price: $95
Updated: 2021/12/16

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1-BENZHYDRYLPIPERAZINE Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystalline powder

Uses

Cinnarizine (C465300) impurity.

Uses

1-(Diphenylmethyl)piperazine [N-(Diphenylmethyl)piperazine] may be used for the synthesis of 2-nitro-3,4,4-trichloro-1-(propylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene and 2-nitro-3,4,4-trichloro-1-(octadecylthio)-1-[4-(diphenylmethyl)piperazin-1-yl]-1,3-butadiene.

Uses

1-Benzhydrylpiperazine is an intermediate used in drug synthesis

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 1098, 1955 DOI: 10.1021/ja01610a006

General Description

1-(Diphenylmethyl)piperazine is an intermediate during drug synthesis. It has been reported to be formed during the oxidative metabolism of cinnarizine (CZ) [1-(diphenylmethyl)-4-(3-phenyl-2-propenyl)-piperazine] in rat liver microsomes. It reacts with quinone in acetonitrile, followed by oxidation with an alkaline potassium ferricyanide, to afford 4-amino-3,6-di(tert-butyl)-o-benzoquinones.

Flammability and Explosibility

Not classified

1-BENZHYDRYLPIPERAZINE Preparation Products And Raw materials

Raw materials

Piperazine Dilute hydrochloric acid Benzhydrol Chlorodiphenylmethane

Preparation Products

Meclozine Oxatomide Stugeron

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1-BENZHYDRYLPIPERAZINE Suppliers

Americas 1 Belgium 1 Canada 1 China 193 Europe 5 France 1 Germany 9 India 78 Japan 6 Russia 2 Slovakia 1 South Korea 1 Switzerland 4 The Netherlands 1 Ukraine 2 United Kingdom 14 United States 52 Global 372

TOKYO CHEMICAL INDUSTRY CO., LTD.

Tel: 03-36680489
Fax: 03-3668-0520
Email: Sales-JP@TCIchemicals.com
Country: Japan
ProdList: 28387
Advantage: 80

Hattori Corporation

Tel: --
Fax: --
Email: info@hattoricorp.com
Country: Japan
ProdList: 1254
Advantage: 58

K. Sakai & Co., Ltd.

Tel: --
Fax: --
Email: em@ksakai.co.jp
Country: Japan
ProdList: 957
Advantage: 58

Fine Corporation

Tel: --
Fax: --
Email: info@fine-c.jp
Country: Japan
ProdList: 1427
Advantage: 58

Kanto Chemical Co., Inc.

Tel: --
Fax: --
Email: reag-info@gms.kanto.co.jp
Country: Japan
ProdList: 6756
Advantage: 74

Wako Pure Chemical Industries, Ltd.

Tel: --
Fax: --
Email: labchem-tec@wako-chem.co.jp
Country: Japan
ProdList: 6819
Advantage: 80

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View Lastest Price from 1-BENZHYDRYLPIPERAZINE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 1-Benzhydrylpiperazine 841-77-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2023-02-03

Xuchang Hengsheng Pharmaceutical Co., Ltd

Product: 1-(diphenylmethyl)-piperazin 841-77-0
Price: US $0.00/Kg
Min. Order: 1Kg
Purity: ≥99.0%
Supply Ability: 10 Tons
Release date: 2024-08-07

Career Henan Chemical Co

Product: 1-BENZHYDRYLPIPERAZINE 841-77-0
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2019-05-24

841-77-0, 1-BENZHYDRYLPIPERAZINERelated Search:

1-(DiphenylMethyl)-4-[(1RS,3E)-4-phenyl-1-[(E)-2-phenylethenyl)-3-buten-1-yl]piperazine IMp. E (EP): 1,4-Bis(diphenylMethyl)piperazine IMp. C (EP): (4-(DiphenylMethyl)-1,1-bis[(E)-3-phenylprop-2-enyl]piperaziniuM Chloride (Z)-Cinnarizine Chlorodiphenylphosphine CHLORCYCLIZINE Cyclizine 1-BENZHYDRYLPIPERAZINE Hydroxyzine dihydrochloride CHLORCYCLIZINE HYDROCHLORIDE Flunarizine dihydrochloride Meclizine dihydrochloride 4,4'-Difluorobenzhydrylpiperazine 1-(4-Chlorobenzhydryl)piperazine Stugeron 1-(4,4'-DICHLOROBENZHYDRYL)PIPERAZINE Buterizine Piperazine

1-(diphenylmethyl)-piperazin

1-(Diphenylmethyl)piperazine,97%

AKOS BBS-00003601

AKOS NCG1-0108

TIMTEC-BB SBB003136

N-BENZHYDRYLPIPERAZINE

N-BENZYLHYDRYLPIPERAZINE

1-(DIPHENYLMETHYL)PIPERAZINE

1-BENZHYDRYLPIPERAZINE

1-BENZYHYDRYLPIPERAZINE

BENZHYDRYLPIPERAZINE

LABOTEST-BB LT00454383

1-Benzhydrylpiperazine 97%

1-Benzhydrylpiperazine ,99%

Cinnarizine Impurity 1(Cinnarizine EP Impurity A)

Piperazine, 1-(diphenylmethyl)-

4-(DiphenylMethyl)piperazine

NSC 35536

Cinnarizine EP IMpurity A

1-(DiphenylMethyl)piperazine SynonyMs Benzhydrylpiperazine

1-(Diphenylmethyl)piperazine >=98.0% (NT)

1-(Diphenylmethyl)piperazineone

4-benzhydrylpiperazine

Diphenylmethylpiperazine

N-(Diphenylmethyl)piperazine

norcyclizine

Cetirizine SM impurity 1 HCl

1-Benzhydrylpiperazine &gt

1-BENZHYDRYLPIPERAZINE ISO 9001：2015 REACH

Cinnarizine EP Impurity A 841-77-0

Nor-cyclizineQ: What is Nor-cyclizine Q: What is the CAS Number of Nor-cyclizine Q: What is the storage condition of Nor-cyclizine Q: What are the applications of Nor-cyclizine

1-BENZHYDRYLPIPERAZINEidazol-2-one

Benzhydrol piperzine

841-77-0

C20H17N2

C17H20N2

AMINE

Building Blocks

Piperazines

Heterocyclic Building Blocks

Building Blocks

C16 to C29

Chemical Synthesis

Heterocyclic Building Blocks

Piperazines

Heterocycles

Intermediates & Fine Chemicals

Pharmaceuticals

Piperaizine

Piperazine derivates

Aromatics