Atipamezole hydrochloride

Product Name: Atipamezole hydrochloride
CAS No.: 104075-48-1
Chemical Name: Atipamezole hydrochloride
Synonyms: Antisedan;Unii-2W4279571x;Atipamezole HCL;MPV1248 hydrochloride;MPV-1248 hydrochloride;MPV 1248 hydrochloride;Atipamezole hydrochloride;Atipamezole HCl (MPV-1248);Atipamezole hydrochloride, >=99%;4-(2-ethylindan-2-yl)-1H-imidazole
CBNumber: CB81210097
Molecular Formula: C14H16N2.HCl
Formula Weight: 248.75
MOL File: 104075-48-1.mol

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Atipamezole hydrochloride Property

Melting point:: 211-215°
storage temp.: Sealed in dry,Room Temperature
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: White to Off-White
Merck: 14,861
InChI: InChI=1S/C14H16N2.ClH/c1-2-14(13-9-15-10-16-13)7-11-5-3-4-6-12(11)8-14;/h3-6,9-10H,2,7-8H2,1H3,(H,15,16);1H
InChIKey: PCCVCJAQMHDWJY-UHFFFAOYSA-N
SMILES: C1(CC)(CC2=C(C=CC=C2)C1)C1=CNC=N1.Cl
CAS DataBase Reference: 104075-48-1(CAS DataBase Reference)

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Safety

RTECS: NI6139000
HS Code: 2933.29.2000
Toxicity: LD50 in male, female rats (mg/kg): >50, 44 s.c. (Scheinin)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P322Specific measures (see …on this label).

P330Rinse mouth.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: A2956
Product name: Atipamezole Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 25mg
Price: $299
Updated: 2024/03/01

TCI Chemical

Product number: A2956
Product name: Atipamezole Hydrochloride
Purity: >98.0%(HPLC)(T)
Packaging: 100mg
Price: $596
Updated: 2024/03/01

Alfa Aesar

Product number: H37332
Product name: Atipamezole (hydrochloride)
Packaging: 1g
Price: $406
Updated: 2021/12/16

Alfa Aesar

Product number: H37332
Product name: Atipamezole (hydrochloride)
Packaging: 250mg
Price: $123
Updated: 2021/12/16

Cayman Chemical

Product number: 9001181
Product name: Atipamezole (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $72
Updated: 2024/03/01

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Atipamezole hydrochloride Chemical Properties,Usage,Production

Uses

Atipamezole Hydrochloride, is the a synthetic α2-adrenergic antagonist, usually used to reverse the sedative and analgesic effects of dexmedetomidine and medetomidine in dogs. It has also been shown to be used as possible anti-Parkinsonian drug in humans.

Biological Activity

Selective α 2 -adrenergic receptor antagonist (K i values are 1.1, 1.0, 0.89, 1300 and 6500 nM for α 2A , α 2B , α 2C , α 1A and α 1B receptors respectively). Brain penetrant.

Side effects

A transient hypotensive effect has been observed during the first 10 minutes post-injection of atipamezole hydrochloride. In rare cases, hyperactivity, tachycardia, salivation, atypical vocalization, muscle tremor, vomiting, increased respiratory rate, uncontrolled urination, and defecation may occur. In very rare cases, recurrence of sedation may occur, or the recovery time may not be shortened after administration of atipamezole. In cats, when using low doses to reverse the effects of medetomidine or dexmedetomidine partially, the possibility of hypothermia (even when aroused from sedation) should be guarded against.

Veterinary Drugs and Treatments

Atipamezole is labeled for use as a reversal agent for medetomidine and dexmedetomidine. It potentially could be useful for reversal of other alpha2-adrenergic agonists as well (e.g., amitraz, xylazine, clonidine, tizanidine, brimonidine).

storage

Desiccate at RT

Atipamezole hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Atipamezole hydrochloride Suppliers

Americas 1 Australia 1 China 163 Europe 1 Germany 1 India 6 Japan 1 Latvia 1 Mexico 1 Philippines 1 South Korea 1 The Netherlands 1 United Kingdom 4 United States 20 Global 203

Suzhou ChemWe Chemical Co., Ltd.

Tel: 512-62706911 13401923197
Fax: 0512-62706910
Email: sales@chemwe.com
Country: China
ProdList: 94
Advantage: 56

Shanghai Mokai Pharmaceutical Technology Co., Ltd.

Tel: 021-60951261 18601606476
Email: nancy@mkpharma.cn
Country: China
ProdList: 453
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel
Fax: 86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2923
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9551
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

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View Lastest Price from Atipamezole hydrochloride manufacturers

airuikechemical co., ltd.

Product: atipamezole hcl 104075-48-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Atipamezole hydrochloride 104075-48-1
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98%
Supply Ability: 10kg/month
Release date: 2021-05-27

Hangzhou ICH Biofarm Co., Ltd

Product: Atipamezole hydrochloride 104075-48-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99% HPLC
Supply Ability: 100kg
Release date: 2023-07-05

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104075-48-1

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