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Quinazoline

Product Name
Quinazoline
CAS No.
253-82-7
Chemical Name
Quinazoline
Synonyms
PHENMIAZINE;1,3-BENZODIAZINE;5,6-Benzopyrimidine;QUINAZOLINE;Quinazoline 99%;Benzopyrimidine;Quinazoline >Quinazoline ,98%;Benzo[d]pyrimidine;benzo[a]pyrimidine
CBNumber
CB8181293
Molecular Formula
C8H6N2
Formula Weight
130.15
MOL File
253-82-7.mol
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Quinazoline Property

Melting point:
46-48 °C (lit.)
Boiling point:
243 °C (lit.)
Density 
1.2002 (rough estimate)
refractive index 
1.6231 (estimate)
Flash point:
224 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
H2O: freely soluble
pka
3.43(at 20℃)
form 
Crystalline Powder, Crystals and/or Chunks
color 
Yellow to beige to brownish
Merck 
14,8053
BRN 
109370
CAS DataBase Reference
253-82-7(CAS DataBase Reference)
NIST Chemistry Reference
Quinazoline(253-82-7)
EPA Substance Registry System
Quinazoline (253-82-7)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36-26-23
WGK Germany 
3
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
123323
Product name
Quinazoline
Purity
99%
Packaging
1g
Price
$73.4
Updated
2024/03/01
Sigma-Aldrich
Product number
123323
Product name
Quinazoline
Purity
99%
Packaging
5g
Price
$237
Updated
2024/03/01
TCI Chemical
Product number
Q0055
Product name
Quinazoline
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$120
Updated
2024/03/01
Alfa Aesar
Product number
B24094
Product name
Quinazoline, 98%
Packaging
1g
Price
$36.6
Updated
2021/12/16
Alfa Aesar
Product number
B24094
Product name
Quinazoline, 98%
Packaging
5g
Price
$126
Updated
2021/12/16
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Quinazoline Chemical Properties,Usage,Production

Chemical Properties

Beige to brownish crystalline powder

Uses

Quinazoline was used to study the electrochemical behaviour of quinazoline using modern polarographic and voltammetric methods. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Definition

ChEBI: A mancude organic heterobicyclic parent that is naphthalene in which the carbon atoms at positions 1 and 3 have been replaced by nitrogen atoms.

General Description

Quinazolines has applications in medicinal chemistry due to their antibacterial, antifungal, anticonvulsant, anti-inflammatory and antitumor activities. It is the basic structural unit of pharmaceuticals and plays an important role in modern synthesis of antitumor drugs.

Biochem/physiol Actions

Genotoxicity of quinazoline was established by bacterial SOS Chromotest (Escherichia Coli).

Purification Methods

Purify quinazoline by passage through an activated alumina column in *C6H6 or pet ether (b 40-60o). Distil it under reduced pressure, sublime it under vacuum and crystallise it from pet ether. The picrate has m 188-189o (from MeOH). [Armarego J Appl Chem 11 70 1961, Armarego Quinazolines, Fused Pyrimidines Part I Brown Ed, Wiley-Interscience 1967, Brown Quinazolines Supplement I Taylor Ed, Wiley-Interscience 1996, ISBN 0-471-14565-3; for covalent hydration see Albert & Armarego Adv Heterocycl Chem 4 1 1965, Beilstein 23 H 175, 23 II 177, 23 III/IV 1221.]

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Quinazoline Suppliers

Acros Organics (Part of Thermo Fisher Scientific )
Tel
--
Fax
--
Email
fo@acros.com
Country
Belgium
ProdList
3824
Advantage
58
Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from Quinazoline manufacturers

Career Henan Chemical Co
Product
Quinazoline 253-82-7
Price
US $98.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2018-08-04

253-82-7, QuinazolineRelated Search:


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