ChemicalBook > CAS DataBase List > 2-Fluoro-5-nitropyridine

2-Fluoro-5-nitropyridine

Product Name
2-Fluoro-5-nitropyridine
CAS No.
456-24-6
Chemical Name
2-Fluoro-5-nitropyridine
Synonyms
uoro-5-nitropyridine;6-FLUORO-3-NITROPYRIDINE;2-FLUORO-5-NITROPYRIDINE;Pyridine, 2-fluoro-5-nitro-;2-Fluoro-5-nitropyridine >2-Fluoro-5-nitropyridine ISO 9001：2015 REACH
CBNumber
CB8239783
Molecular Formula
C5H3FN2O2
Formula Weight
142.09
MOL File
456-24-6.mol
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2-Fluoro-5-nitropyridine Property

Melting point:
142-144 C
Boiling point:
86-87℃/7mm lit.
Density 
4,64g/cm
refractive index 
1.5250
storage temp. 
Inert atmosphere,Room Temperature
form 
Liquid
pka
-4.47±0.10(Predicted)
color 
Colorless to pale yellow
Water Solubility 
Slightly soluble in water.
Sensitive 
Moisture Sensitive
CAS DataBase Reference
456-24-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-22
Safety Statements 
36
RIDADR 
UN 1549
HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
F0983
Product name
2-Fluoro-5-nitropyridine
Purity
>98.0%(GC)
Packaging
5g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
F0983
Product name
2-Fluoro-5-nitropyridine
Purity
>98.0%(GC)
Packaging
25g
Price
$103
Updated
2024/03/01
Alfa Aesar
Product number
H64210
Product name
2-Fluoro-5-nitropyridine, 98%
Packaging
5g
Price
$42.65
Updated
2024/03/01
Alfa Aesar
Product number
H64210
Product name
2-Fluoro-5-nitropyridine, 98%
Packaging
25g
Price
$184.65
Updated
2024/03/01
TRC
Product number
F597683
Product name
2-Fluoro-5-nitropyridine
Packaging
1g
Price
$75
Updated
2021/12/16
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2-Fluoro-5-nitropyridine Chemical Properties,Usage,Production

Uses

It is used in the preparation of nitropyridines by nitration of pyridines with nitric acid.

Uses

2-Fluoro-5-nitropyridine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis


Synthesis of 5-amino-2-fluoropyridine. A mixture of 5-nitro-2-chloropyridine (2.0 g, 12.6 mmol) and anhydrous potassium fluoride (2.2 g, 38 mmol) in a combination of sulfalone ( 6 mL) and benzene (4 mL) was stirred at RT for 20 min. The benzene was then removed by distillation. The resulting mixture was heated at 150 ??C for 12h. The mixture was cooled to RT whereupon water (60 mL) was added. The desired product was separated from the solution via steam distillation. Extraction of the distillate with diethyl ether (2 ?á 1 0 mL) followed by drying (Na2SO4) and concentration gave the compound. 5-nitro-2-fluoropyridine, water white oil (1.3 g, 73%).

2-Fluoro-5-nitropyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluoro-5-nitropyridine Suppliers

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View Lastest Price from 2-Fluoro-5-nitropyridine manufacturers

Henan Fengda Chemical Co., Ltd
Product
2-Fluoro-5-nitropyridine 456-24-6
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Shaanxi Dideu Medichem Co. Ltd
Product
2-Fluoro-5-nitropyridine 456-24-6
Price
US $1.00-1.00/Kg/Drum
Min. Order
1g
Purity
98%
Supply Ability
50tons
Release date
2020-05-12
Dideu Industries Group Limited
Product
2-Fluoro-5-nitropyridine 456-24-6
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons min
Release date
2021-09-08

456-24-6, 2-Fluoro-5-nitropyridineRelated Search:

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  • 2-FLUORO-5-NITROPYRIDINE
  • 6-FLUORO-3-NITROPYRIDINE
  • 2-Fluoro-5-nitropyridine &gt
  • uoro-5-nitropyridine
  • Pyridine, 2-fluoro-5-nitro-
  • 2-Fluoro-5-nitropyridine ISO 9001：2015 REACH
  • 456-24-6
  • C5H3N2O2F
  • Fluorine series
  • blocks
  • FluoroCompounds
  • NitroCompounds
  • Pyridines
  • Pyridine
  • Pyridine series
  • Boronic Acid
  • Fluorin-contained pyridine series