2-Fluoro-5-nitropyridine
- Product Name
- 2-Fluoro-5-nitropyridine
- CAS No.
- 456-24-6
- Chemical Name
- 2-Fluoro-5-nitropyridine
- Synonyms
- uoro-5-nitropyridine;6-FLUORO-3-NITROPYRIDINE;2-FLUORO-5-NITROPYRIDINE;Pyridine, 2-fluoro-5-nitro-;2-Fluoro-5-nitropyridine >2-Fluoro-5-nitropyridine ISO 9001：2015 REACH
- CBNumber
- CB8239783
- Molecular Formula
- C5H3FN2O2
- Formula Weight
- 142.09
- MOL File
- 456-24-6.mol
2-Fluoro-5-nitropyridine Property
- Melting point:
- 142-144 C
- Boiling point:
- 86-87℃/7mm lit.
- Density
- 4,64g/cm
- refractive index
- 1.5250
- storage temp.
- Inert atmosphere,Room Temperature
- form
- Liquid
- pka
- -4.47±0.10(Predicted)
- color
- Colorless to pale yellow
- Water Solubility
- Slightly soluble in water.
- Sensitive
- Moisture Sensitive
- CAS DataBase Reference
- 456-24-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn
- Risk Statements
- 20/21/22-22
- Safety Statements
- 36
- RIDADR
- UN 1549
- HS Code
- 2933399990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- F0983
- Product name
- 2-Fluoro-5-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $26
- Updated
- 2024/03/01
- Product number
- F0983
- Product name
- 2-Fluoro-5-nitropyridine
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $103
- Updated
- 2024/03/01
- Product number
- H64210
- Product name
- 2-Fluoro-5-nitropyridine, 98%
- Packaging
- 5g
- Price
- $42.65
- Updated
- 2024/03/01
- Product number
- H64210
- Product name
- 2-Fluoro-5-nitropyridine, 98%
- Packaging
- 25g
- Price
- $184.65
- Updated
- 2024/03/01
- Product number
- F597683
- Product name
- 2-Fluoro-5-nitropyridine
- Packaging
- 1g
- Price
- $75
- Updated
- 2021/12/16
2-Fluoro-5-nitropyridine Chemical Properties,Usage,Production
Uses
It is used in the preparation of nitropyridines by nitration of pyridines with nitric acid.
Uses
2-Fluoro-5-nitropyridine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.
Synthesis
Synthesis of 5-amino-2-fluoropyridine. A mixture of 5-nitro-2-chloropyridine (2.0 g, 12.6 mmol) and anhydrous potassium fluoride (2.2 g, 38 mmol) in a combination of sulfalone ( 6 mL) and benzene (4 mL) was stirred at RT for 20 min. The benzene was then removed by distillation. The resulting mixture was heated at 150 ??C for 12h. The mixture was cooled to RT whereupon water (60 mL) was added. The desired product was separated from the solution via steam distillation. Extraction of the distillate with diethyl ether (2 ?á 1 0 mL) followed by drying (Na2SO4) and concentration gave the compound. 5-nitro-2-fluoropyridine, water white oil (1.3 g, 73%).
2-Fluoro-5-nitropyridine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluoro-5-nitropyridine Suppliers
- Tel
- --
- Fax
- --
- nfo@matrix-fine-chemicals.com
- Country
- Switzerland
- ProdList
- 6968
- Advantage
- 58
View Lastest Price from 2-Fluoro-5-nitropyridine manufacturers
- Product
- 2-Fluoro-5-nitropyridine 456-24-6
- Price
- US $5.00-0.10/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-08
- Product
- 2-Fluoro-5-nitropyridine 456-24-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.00%
- Supply Ability
- 100 Tons min
- Release date
- 2021-09-08
- Product
- 2-Fluoro-5-nitropyridine 456-24-6
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-24