4-Chloro-3-nitroaniline
- Product Name
- 4-Chloro-3-nitroaniline
- CAS No.
- 635-22-3
- Chemical Name
- 4-Chloro-3-nitroaniline
- Synonyms
- 4-Chlor-3-nitroanilin;4-chloro-3-nitro-anilin;3-NITRO-4-CHLOROANILINE;4-CHLORO-3-NITROANILINE;Aniline, 4-chloro-3-nitro-;4-Chloro-3-nitrobenzenamine;4-chloro-3-nitro-benzenamin;4-Chloro-3-nitroaniline,97%;4-Chloro-3-nitroaniline >5-Amino-2-chloronitrobenzene
- CBNumber
- CB8264060
- Molecular Formula
- C6H5ClN2O2
- Formula Weight
- 172.57
- MOL File
- 635-22-3.mol
4-Chloro-3-nitroaniline Property
- Melting point:
- 99-101 °C (lit.)
- Boiling point:
- 200°C (rough estimate)
- Density
- 1.5610 (rough estimate)
- refractive index
- 1.5870 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- pka
- 1.87±0.10(Predicted)
- form
- powder to crystal
- color
- White to Yellow to Orange
- BRN
- 1309394
- InChI
- InChI=1S/C6H5ClN2O2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H,8H2
- InChIKey
- FOHHWGVAOVDVLP-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(Cl)C([N+]([O-])=O)=C1
- CAS DataBase Reference
- 635-22-3(CAS DataBase Reference)
- NIST Chemistry Reference
- Benzenamine, 4-chloro-3-nitro-(635-22-3)
- EPA Substance Registry System
- 4-Chloro-3-nitroaniline (635-22-3)
Safety
- Hazard Codes
- T+,N,T
- Risk Statements
- 26/27/28-33-51/53
- Safety Statements
- 28-36/37-45-61-28A
- RIDADR
- UN 2237 6.1/PG 3
- WGK Germany
- 3
- RTECS
- BX1750000
- Hazard Note
- Very Toxic
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29214210
- Hazardous Substances Data
- 635-22-3(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H300Fatal if swallowed
H310Fatal in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H330Fatal if inhaled
H373May cause damage to organs through prolonged or repeated exposure
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P262Do not get in eyes, on skin, or on clothing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P302+P350IF ON SKIN: Gently wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P314Get medical advice/attention if you feel unwell.
P320Specific treatment is urgent (see … on this label).
P330Rinse mouth.
P391Collect spillage. Hazardous to the aquatic environment
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C1138
- Product name
- 4-Chloro-3-nitroaniline
- Purity
- >99.0%(GC)(T)
- Packaging
- 25g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- C1138
- Product name
- 4-Chloro-3-nitroaniline
- Purity
- >99.0%(GC)(T)
- Packaging
- 500g
- Price
- $116
- Updated
- 2021/12/16
- Product number
- HCH0023453
- Product name
- 4-CHLORO-3-NITROANILINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $128.1
- Updated
- 2021/12/16
- Product number
- 081157
- Product name
- 4-Chloro-3-nitroaniline
- Purity
- 97%
- Packaging
- 50g
- Price
- $135
- Updated
- 2021/12/16
- Product number
- FC170383
- Product name
- 4-Chloro-3-nitroaniline
- Packaging
- 100g
- Price
- $150
- Updated
- 2021/12/16
4-Chloro-3-nitroaniline Chemical Properties,Usage,Production
Chemical Properties
ochre powder
Uses
Intermediate in the manufacture of azo dyes, pharmaceuticals, and other organic compounds.
Application
Commercial 4-chloro-3-nitroaniline could be used as a starting material for 3-azido-4-chlorophenylisothiocyanate through a 5-step synthesis. In order to research the impact of the strain on the metabolite profile of plasma samples in rats, 45 mg/kg bw/day 4-chloro-3-nitroaniline (4C3N) was evaluated for 4 weeks. 4C3N administration led to extravascular hemolytic anemia with a few metabolome changes, which were strain-dependent [1-2].
Hazard
Toxic by ingestion and inhalation.
Safety Profile
Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx and Cl-.
References
[1] H. Lamotte. “Synthesis of N‐(3‐azido‐4‐chlorophenyl)‐N′‐[3H‐methyl] thiourea, an efficient photoaffinity probe for the urea carrier.” Journal of Labelled Compounds and Radiopharmaceuticals 42 1 (1994): 289–295.
[2] O’Donoghue, John L. “Subchronic oral toxicology of 4-chloro-3-nitroaniline in the rat.” Fundamental and Applied Toxicology 6 3 (1986): Pages 551-558.
4-Chloro-3-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Chloro-3-nitroaniline manufacturers
- Product
- 4-Chloro-3-nitroaniline 635-22-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2019-12-30
- Product
- 4-Chloro-3-nitroaniline 635-22-3
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-09