4-Chloro-3-nitroaniline

Product Name: 4-Chloro-3-nitroaniline
CAS No.: 635-22-3
Chemical Name: 4-Chloro-3-nitroaniline
Synonyms: 4-Chlor-3-nitroanilin;4-chloro-3-nitro-anilin;3-NITRO-4-CHLOROANILINE;4-CHLORO-3-NITROANILINE;Aniline, 4-chloro-3-nitro-;4-Chloro-3-nitrobenzenamine;4-chloro-3-nitro-benzenamin;4-Chloro-3-nitroaniline,97%;4-Chloro-3-nitroaniline >5-Amino-2-chloronitrobenzene
CBNumber: CB8264060
Molecular Formula: C6H5ClN2O2
Formula Weight: 172.57
MOL File: 635-22-3.mol

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4-Chloro-3-nitroaniline Property

Melting point:: 99-101 °C (lit.)
Boiling point:: 200°C (rough estimate)
Density: 1.5610 (rough estimate)
refractive index: 1.5870 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
pka: 1.87±0.10(Predicted)
form: powder to crystal
color: White to Yellow to Orange
BRN: 1309394
InChI: InChI=1S/C6H5ClN2O2/c7-5-2-1-4(8)3-6(5)9(10)11/h1-3H,8H2
InChIKey: FOHHWGVAOVDVLP-UHFFFAOYSA-N
SMILES: C1(N)=CC=C(Cl)C([N+]([O-])=O)=C1
CAS DataBase Reference: 635-22-3(CAS DataBase Reference)
NIST Chemistry Reference: Benzenamine, 4-chloro-3-nitro-(635-22-3)
EPA Substance Registry System: 4-Chloro-3-nitroaniline (635-22-3)

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Safety

Hazard Codes: T+,N,T
Risk Statements: 26/27/28-33-51/53
Safety Statements: 28-36/37-45-61-28A
RIDADR: UN 2237 6.1/PG 3
WGK Germany: 3
RTECS: BX1750000
Hazard Note: Very Toxic
TSCA: Yes
HazardClass: 6.1
PackingGroup: III
HS Code: 29214210
Hazardous Substances Data: 635-22-3(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H300Fatal if swallowed

H310Fatal in contact with skin

H315Causes skin irritation

H319Causes serious eye irritation

H330Fatal if inhaled

H373May cause damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P302+P350IF ON SKIN: Gently wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P314Get medical advice/attention if you feel unwell.

P320Specific treatment is urgent (see … on this label).

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C1138
Product name: 4-Chloro-3-nitroaniline
Purity: >99.0%(GC)(T)
Packaging: 25g
Price: $20
Updated: 2024/03/01

TCI Chemical

Product number: C1138
Product name: 4-Chloro-3-nitroaniline
Purity: >99.0%(GC)(T)
Packaging: 500g
Price: $116
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: HCH0023453
Product name: 4-CHLORO-3-NITROANILINE
Purity: 95.00%
Packaging: 1G
Price: $128.1
Updated: 2021/12/16

Matrix Scientific

Product number: 081157
Product name: 4-Chloro-3-nitroaniline
Purity: 97%
Packaging: 50g
Price: $135
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC170383
Product name: 4-Chloro-3-nitroaniline
Packaging: 100g
Price: $150
Updated: 2021/12/16

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4-Chloro-3-nitroaniline Chemical Properties,Usage,Production

Chemical Properties

ochre powder

Uses

Intermediate in the manufacture of azo dyes, pharmaceuticals, and other organic compounds.

Application

Commercial 4-chloro-3-nitroaniline could be used as a starting material for 3-azido-4-chlorophenylisothiocyanate through a 5-step synthesis. In order to research the impact of the strain on the metabolite profile of plasma samples in rats, 45 mg/kg bw/day 4-chloro-3-nitroaniline (4C3N) was evaluated for 4 weeks. 4C3N administration led to extravascular hemolytic anemia with a few metabolome changes, which were strain-dependent [1-2].

Hazard

Toxic by ingestion and inhalation.

Safety Profile

Poison by ingestion and intraperitoneal routes. Experimental reproductive effects. Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx and Cl-.

References

[1] H. Lamotte. “Synthesis of N‐(3‐azido‐4‐chlorophenyl)‐N′‐[3H‐methyl] thiourea, an efficient photoaffinity probe for the urea carrier.” Journal of Labelled Compounds and Radiopharmaceuticals 42 1 (1994): 289–295.
[2] O’Donoghue, John L. “Subchronic oral toxicology of 4-chloro-3-nitroaniline in the rat.” Fundamental and Applied Toxicology 6 3 (1986): Pages 551-558.

4-Chloro-3-nitroaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-3-nitroaniline Suppliers

Americas 1 Belgium 1 China 98 Europe 2 Germany 4 India 4 Japan 3 Slovakia 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 27 Global 153

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
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Alfa Aesar

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Energy Chemical

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Shandong Xiya Chemical Co., Ltd

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Syntechem Co.,Ltd

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View Lastest Price from 4-Chloro-3-nitroaniline manufacturers

Career Henan Chemical Co

Product: 4-Chloro-3-nitroaniline 635-22-3
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-09

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4-Chloro-3-nitroaniline ISO 9001：2015 REACH

635-22-3

C6H5N2ClO2

Amines

Building Blocks

C2 to C6

Organic Building Blocks

Nitrogen Compounds

Amines

Building Blocks

C6

Chemical Synthesis

Nitrogen Compounds

Organic Building Blocks

Aromatics Compounds

Intermediates of Dyes and Pigments