ChemicalBook > CAS DataBase List > Bromo-PEG3-t-butyl ester

Bromo-PEG3-t-butyl ester

Product Name
Bromo-PEG3-t-butyl ester
CAS No.
782475-37-0
Chemical Name
Bromo-PEG3-t-butyl ester
Synonyms
Br-PEG3-C2-Boc;Br-PEG3-COOtBu;CAS_782475-37-0;Bromo-peg3-t-butyl;Br-PEG3-CH2CH2COOtBu;Br-PEG3-t-butyl ester;Bromo-PEG3-tert-butyl Ester;tert-butyl 3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)propanoate;Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester;Br-PEG3-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB83062447
Molecular Formula
C13H25BrO5
Formula Weight
341.24
MOL File
782475-37-0.mol
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Bromo-PEG3-t-butyl ester Property

Boiling point:
375.4±27.0 °C(Predicted)
Density 
1.223±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
solubility 
Soluble in DCM
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C13H25BrO5/c1-13(2,3)19-12(15)4-6-16-8-10-18-11-9-17-7-5-14/h4-11H2,1-3H3
InChIKey
ISAHSVMMFPHXFG-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCOCCOCCOCCBr
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-20683
Product name
Bromo-PEG3-t-butylester
Purity
98%
Packaging
250mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-20683
Product name
Bromo-PEG3-t-butylester
Purity
98%
Packaging
500mg
Price
$450
Updated
2021/12/16
AK Scientific
Product number
5639DP
Product name
Bromo-PEG3-t-butylester
Packaging
250mg
Price
$455
Updated
2021/12/16
BroadPharm
Product number
BP-20683
Product name
Bromo-PEG3-t-butylester
Purity
98%
Packaging
1g
Price
$850
Updated
2021/12/16
BroadPharm
Product number
BP-20683
Product name
Bromo-PEG3-t-butylester
Purity
98%
Packaging
5G
Price
$1800
Updated
2021/12/16
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Bromo-PEG3-t-butyl ester Chemical Properties,Usage,Production

Description

Bromo-PEG3-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Br-PEG3-C2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG3-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Bromo-PEG3-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Br-PEG3-COOtBu 782475-37-0
Price
US $0.00/g
Min. Order
10g
Purity
>98.00%
Supply Ability
10g
Release date
2024-03-25
Career Henan Chemical Co
Product
Bromo-PEG3-t-butyl ester 782475-37-0
Price
US $2.00/g
Min. Order
1g
Purity
95~99.9%
Supply Ability
5KG
Release date
2020-03-05

782475-37-0, Bromo-PEG3-t-butyl esterRelated Search:


  • tert-butyl 3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)propanoate
  • Br-PEG3-t-butyl ester
  • Br-PEG3-CH2CH2COOtBu
  • CAS_782475-37-0
  • Br-PEG3-COOtBu
  • Br-PEG3-C2-Boc
  • Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Bromo-peg3-t-butyl
  • Br-PEG3-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Bromo-PEG3-tert-butyl Ester
  • 782475-37-0
  • C13H25BrO5