Description References
ChemicalBook > CAS DataBase List > Isobutyraldehyde

Isobutyraldehyde

Description References
Product Name
Isobutyraldehyde
CAS No.
78-84-2
Chemical Name
Isobutyraldehyde
Synonyms
2-METHYLPROPANAL;methylpropanal;ISOBUTYLALDEHYDE;Isobutanal;isobutyral;sobutyraldehyde;Isobutyraldehyd;2-methyl-propana;Propanal,2-methyl-;ISOBUTYRIC ALDEHYDE
CBNumber
CB8350684
Molecular Formula
C4H8O
Formula Weight
72.11
MOL File
78-84-2.mol
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Isobutyraldehyde Property

Melting point:
-65 °C (lit.)
Boiling point:
63 °C (lit.)
Density 
0.79 g/mL at 25 °C (lit.)
vapor density 
2.5 (vs air)
vapor pressure 
66 mm Hg ( 4.4 °C)
refractive index 
n20/D 1.374(lit.)
FEMA 
2220 | ISOBUTYRALDEHYDE
Flash point:
−40 °F
storage temp. 
Store below +30°C.
solubility 
water: soluble11g/100mL at 20°C(lit.)
form 
Liquid
color 
Clear
Odor
Pungent.
Odor Threshold
0.00035ppm
Odor Type
aldehydic
explosive limit
1.6-11.0%(V)
Water Solubility 
75 g/L (20 ºC)
Sensitive 
Air Sensitive
Merck 
14,5154
JECFA Number
252
BRN 
605330
Stability:
Stable. Refrigerate. Highly flammable. Incompatible with strong oxidizing agents, strong bases, strong acids, strong reducing agents.
LogP
0.77 at 25℃
CAS DataBase Reference
78-84-2(CAS DataBase Reference)
NIST Chemistry Reference
Propanal, 2-methyl-(78-84-2)
EPA Substance Registry System
Isobutyraldehyde (78-84-2)
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Safety

Hazard Codes 
F,Xn,Xi
Risk Statements 
11-22-36
Safety Statements 
16-36/37-9-33-29-26
RIDADR 
UN 2045 3/PG 2
WGK Germany 
1
RTECS 
NQ4025000
F 
9-13-23
Autoignition Temperature
384 °F
TSCA 
Yes
HS Code 
2912 19 00
HazardClass 
3
PackingGroup 
II
Hazardous Substances Data
78-84-2(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 3.7 g/kg (Smyth)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W222011
Product name
Isobutyraldehyde
Purity
natural, 96%, FG
Packaging
25g
Price
$95.9
Updated
2024/03/01
Sigma-Aldrich
Product number
W222011
Product name
Isobutyraldehyde
Purity
natural, 96%, FG
Packaging
100g
Price
$193
Updated
2024/03/01
Sigma-Aldrich
Product number
W222011
Product name
Isobutyraldehyde
Purity
natural, 96%, FG
Packaging
1kg
Price
$1250
Updated
2024/03/01
Sigma-Aldrich
Product number
W222003
Product name
Isobutyraldehyde
Purity
≥98%, FG
Packaging
1kg
Price
$106
Updated
2024/03/01
Sigma-Aldrich
Product number
W222003
Product name
Isobutyraldehyde
Purity
≥98%, FG
Packaging
4kg
Price
$250
Updated
2024/03/01
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Isobutyraldehyde Chemical Properties,Usage,Production

Description

Isobutyraldehyde, also known as 2-Methylpropanal, is an organic compound belonging to the family of aldehydes, which can be found in alcoholic beverages, tea, breads, cooked pork, spearmint oil as well as fresh fruits, such as apple, banana, cherry, etc. It is manufactured by the hydroformylation of propene, usually obtained as a side-product. It can be applied as a source for producing other chemicals, including isobutyl alcohol, neopentyl glycol as well as isobutanoic acid production and used to produce amino acids such as valine and leucine. Besides, isobutyraldehyde commonly serves as an intermediate in the field of chemical industry for manufacture of pharmaceuticals (such as Vitamin B5), crop protection products, pesticides, synthetic resins, antioxidants, vulcanisation accelerators, textile auxiliaries, perfumery and flavors.

References

https://pubchem.ncbi.nlm.nih.gov/compound/isobutyraldehyde#section=Top
http://chemindustry.ru/Isobutyraldehyde.php
http://product-finder.basf.com/group/corporate/product-finder/en/brand/ISOBUTYRALDEHYDE
https://en.wikipedia.org/wiki/Isobutyraldehyde

Description

Isobutyraldehyde has a characteristic odor. Synthesized via oxidation of isobutyl alcohol with potassium dichromate and concentrated sulfuric acid.

Chemical Properties

Isobutyraldehyde has a characteristic sharp, pungent odor. Industrially, it is mainly hydrogenated to produce isobutanol. The addition reaction of isobutyraldehyde and formaldehyde produces hydroxytrimethylacetaldehyde, which is then hydrogenated to form neopentyl glycol, which is used as a raw material for varnishes, resins, fibers and lubricants.

Physical properties

colourless liquid with an extremely unpleasant smell. Miscible in ethanol, benzene, carbon disulfide, acetone, toluene, chloroform and ether, slightly soluble in water (1:125).

Occurrence

Reported found in apple and currant aromas and in the essential oils from tobacco leaves and tea leaves, also in the essential oils of Pinus jeffreyi Murr. leaves, Citrus aurantium leaves, and Datura stramonium. Reported found in apple, banana, sweet and sour cherry, currants, kohlrabi, carrots, celery, peas, potato, tomato, peppermint, corn mint and spearmint oil, vinegar, wheat and rye breads, cheeses, butter, yogurt, egg, caviar, fatty fish, meats, hop oil, beer, brandy, rum, sherry, cider, whiskies, grape wines, cocoa, coffee, tea, filberts, peanuts, popcorn, oats, soybeans, honey, mushrooms, macadamia nuts, cauliflower, pear and apple brandy, rice, sukiyaki, malt, loquat, clary sage, shrimps, truffle, scallops and squid

Uses

Isobutyraldehyde is used in the synthesisof cellulose esters, resins, and plasticizers;in the preparation of pantothenic acid andvaline; and in flavors.

Uses

Isobutyraldehyde is used as an intermediate in the preparation of isobutanol, methacrolein, hydroxypivaldehyde and neopentyl glycol. It is actively involved in the Cannizaro reaction. It is also used as an intermediate to prepare pharmaceuticals, agrochemicals, vitamins, antioxidants, rubber accelerators, textile auxiliaries, perfumery and flavors.

Uses

In the synthesis of pantothenic acid, valine, leucine, cellulose esters, perfumes, flavors, plasticizers, resins, gasoline additives.

Preparation

By oxidation of isobutyl alcohol with potassium dichromate and concentrated sulfuric acid.
Catalytic synthesis of isobutyraldehyde from methanol and n-propyl alcohol over titanium oxide-supported vanadium oxide catalysts

Definition

ChEBI: Isobutyraldehyde is a member of the class of propanals that is propanal substituted by a methyl group at position 2. It has a role as a Saccharomyces cerevisiae metabolite. It is a member of propanals and a 2-methyl-branched fatty aldehyde.

Aroma threshold values

Detection: 0.4 to 43 ppb

General Description

Isobutyl aldehyde appears as a clear colorless liquid with a pungent odor. Flash point of -40°F. Less dense than water and insoluble in water. Hence floats on water. Vapors are heavier than air. Used to make other chemicals.

Air & Water Reactions

Highly flammable. Oxidizes slowly on exposure to air. Stable (less than 10% decomposition) for four hours when exposed to light and air in a closed system. Stable for two weeks when stored under nitrogen at temperatures up to 77°F. Insoluble in water.

Reactivity Profile

Isobutyraldehyde can react vigorously with reducing agents, with oxidizing agents, strong bases and mineral acids. Can undergo exothermic self-condensation or polymerization reactions that are often catalyzed by acid. Generates flammable and/or toxic gases in combination with azo, diazo compounds, dithiocarbamates, nitrides, and strong reducing agents. Reacts slowly when exposed to air with air to give peroxides and other products. These reactions are activated by light, catalyzed by salts of transition metals, and are autocatalytic (catalyzed by their products). The addition of stabilizers (antioxidants) retards autoxidation.

Hazard

Highly flammable, dangerous fire and explosion risk. Irritant to skin and eyes.

Health Hazard

Vapor is irritating to the eyes and mucous membranes.

Health Hazard

Isobutyraldehyde is a moderate skin and eyeirritant; the effect may be slightly greaterthan that of n-butyraldehyde. An amounttotaling 500 mg in 24 hours produced severeskin irritation in rabbits; 100 mg causedmoderate eye irritation.
The toxicity of isobutyraldehyde determinedon test animals was very low. Exposureto 8000 ppm (23,600 mg/m3) for 4 hours waslethal to rats.
LD50 value, oral (rats): 2810 mg/kg.

Fire Hazard

Behavior in Fire: Vapors are heavier than air and may travel considerable distance to a source of ignition and flash back. Fires are difficult to control due to ease of reignition.

Flammability and Explosibility

Flammable

Chemical Reactivity

Reactivity with Water No reaction; Reactivity with Common Materials: No reactions; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.

Carcinogenicity

Isobutyraldehyde is not mutagenic in various strains of S. typhimurium and is noncarcinogenic in rats and mice.

Purification Methods

Dry isobutyraldehyde with CaSO4 and use it immediately after distillation under nitrogen because of the great difficulty in preventing oxidation. It can be purified through its acid bisulfite derivative. [Beilstein 1 IV 3262.]

Waste Disposal

Isobutyraldehyde is burned in a chemicalincinerator equipped with an afterburner andscrubber.

Isobutyraldehyde Preparation Products And Raw materials

Raw materials

CARBON MONOXIDE 2-Amino-3-chlorobenzoic acid 2-Methyl-1-propanol PROPYLENE Potassium dichromate Butyraldehyde Concentrated sulfuric acid

Preparation Products

1-CHLORO-2-METHYLPROPYL CHLOROFORMATE 2,2,4-Trimethyl-1,3-pentanediol monoisobutyrate 3-Methyl-2-butanone GERANYL ISOBUTYRATE Carbosulfan 2-Methyl-1-propanol FENPROPIMORPH Isobutyric acid L-Valine 2,6-Dimethyl-5-heptenal Calcium D-Pantothenate D-(-)-PANTOLACTONE Neopentyl glycol monoester hydropivalicate 1-CHLORO-2-METHYL-1-PROPENE N,N''-(isobutylidene)diurea DL-Valine 5-METHYL-3-HEXEN-2-ONE DL-Pantolactone Rifapentine 2-ISOPROPYL-6-METHYL-4-PYRIMIDINOL Butyraldehyde ALDICARB-OXIME 3-Hydroxy-2,2-dimethylpropanal 2-Methylbutyl 2-methylbutyrate 2-AMINO-3-METHYLBUTANENITRILE 2,5-Dimethyl-2,4-hexadiene Methyl methacrylate neopentyl glycol 1-Butanol Isobutylamine cyclamen aldehyde Isobutyronitrile
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View Lastest Price from Isobutyraldehyde manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
iso-butyl aldehyde IBAL 78-84-2
Price
US $1.00/PCS
Min. Order
1PCS
Purity
99%
Supply Ability
100mt
Release date
2024-11-04
Hebei Mojin Biotechnology Co., Ltd
Product
Isobutyraldehyde 78-84-2
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-06-29
Zhuozhou Wenxi import and Export Co., Ltd
Product
Isobutyl aldehyde 78-84-2
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10

78-84-2, IsobutyraldehydeRelated Search:

Propionaldehyde 2,2-Bis(hydroxymethyl)propionic acid Sodium carboxymethyl cellulose Phenylpropyl aldehyde 2,6-Lutidine N,N-Dimethylformamide Isobutyric acid Isobutylene Isopropyl alcohol Isoquinoline Ethyl vanillin isobutyrate 2-Methyl-1-propanol Isoflurane Isobutyrophenone Methyl isobutyrate Isobutyl isobutyrate Isobutyric anhydride Isobutyryl chloride

  • 2-Formylpropane
  • 2-methyl-propana
  • 2-methylpropanal (isobutanal)
  • Lsobutyra Dehyde
  • Lsobutyral Dehyde
  • sobutyraldehyde
  • Natural Isobutyraldehyde
  • 2-methyl-propionaldehyd
  • alpha-Methylpropionaldehyde
  • Isobutaldehyde
  • Isobutanal
  • iso-Butanal
  • isobutyral
  • Isobutyraldehyd
  • isobutyraldehyd(czech)
  • isobutyric
  • Isobutyryl aldehyde
  • isobutyrylaldehyde
  • iso-C3H7CHO
  • Isopropylaldehyde
  • ISOBUTYRIC ALDEHYDE
  • FEMA 2220
  • DIMETHYL ACETALDEHYDE
  • 2-METHYL-1-PROPANAL
  • 2-METHYLPROPIONALDEHYDE
  • 2-METHYLPROPANAL
  • #niso-Butyraldehyde
  • ISOBUTYRALDEHYDE 98+%
  • ISOBUTYRALDEHYDE 96+% NATURAL
  • ISOBUTYRALDEHYDE, STAB.
  • ISOBUTYRALDEHYDE, REDISTILLED, 99.5+%
  • ISOBUTYRALDEHYDE, DRY, 99.2+%
  • ISOBUTYRALDEHYDE, 99+%
  • isobutyraldehyde,2-methylpropanal
  • ISOBUTYRALDEHYDE, NATURAL
  • 2-Methyl-3-propanone
  • Isobutyraldehyde or 2-Methylpropionaldehyde
  • Isobutyraldehyde,2-Methylpropionaldehyde
  • Isobutyraldehyde 5g [78-84-2]
  • Isobutyraldehyde 1g [78-84-2]
  • ISOBUTYRALDEHYDE, 98+%, FCC
  • Isobutyraldehyde, 99+% 1LT
  • ISOBUTYLALDEHYDE
  • ISOBUTYRALDEHYDE
  • Isopropylcarboxaldehyde
  • Isopropylformaldehyde
  • Methyl propanal
  • methyl-2propanal
  • methylpropanal
  • NCI-C60968
  • Propanal,2-methyl-
  • Propionaldehyde, 2-methyl-
  • so-Butyl aldehyde
  • Valine aldehyde
  • valinealdehyde
  • α-Methylpropionaldehyde
  • Isobutyraldehyde dry, 98%
  • Isobutyraldehyde, Standard for GC,>99.5%(GC)