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Boc-5-aminopentanoic acid

Product Name
Boc-5-aminopentanoic acid
CAS No.
27219-07-4
Chemical Name
Boc-5-aminopentanoic acid
Synonyms
BOC-5-AVA-OH;BOC-5-AMINOVALERIC ACID;5-(TERT-BUTOXYCARBONYLAMINO)VALERIC ACID;BOC-APE(5)-OH;Boc-5-Ava-OH 97%;BOC-NH-(CH2)4-COOH;RARECHEM EM WB 0073;Boc-d-aMinovaleric acid;5-(BOC-AMINO)VALERIC ACID;N-BOC-5-AMINOVALERIC ACID
CBNumber
CB8379946
Molecular Formula
C10H19NO4
Formula Weight
217.26
MOL File
27219-07-4.mol
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Boc-5-aminopentanoic acid Property

Melting point:
48-52 °C(lit.)
Boiling point:
160-168 °C0.8 mm Hg(lit.)
Density 
1.1518 (rough estimate)
refractive index 
1.4500 (estimate)
Flash point:
>230 °F
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
soluble in Methanol
form 
Powder
pka
4.72±0.10(Predicted)
color 
Off-white
BRN 
2048862
CAS DataBase Reference
27219-07-4(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
10-21
HazardClass 
IRRITANT
HS Code 
29241990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
475351
Product name
Boc-5-Ava-OH
Purity
97%
Packaging
5g
Price
$166
Updated
2023/06/20
Sigma-Aldrich
Product number
475351
Product name
Boc-5-Ava-OH
Purity
97%
Packaging
25g
Price
$658
Updated
2023/06/20
TCI Chemical
Product number
B2895
Product name
N-(tert-Butoxycarbonyl)-5-aminovaleric Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$89
Updated
2024/03/01
TCI Chemical
Product number
B2895
Product name
N-(tert-Butoxycarbonyl)-5-aminovaleric Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$301
Updated
2024/03/01
Alfa Aesar
Product number
H66168
Product name
5-(Boc-amino)valeric acid, 95%
Packaging
1g
Price
$26.7
Updated
2023/06/20
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Boc-5-aminopentanoic acid Chemical Properties,Usage,Production

Description

Boc-5-aminopentanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. Boc-5-aminopentanoic acid is an alkane chain with terminal carboxlic acid and Boc-protected amino groups. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Chemical Properties

solid

Uses

Boc-5-aminovaleric acid can be used to synthesize inhibitors of bacterial quorum seining and biofilm formation. It can also be used to synthesize diblock and triblock copolymers.

Synthesis Reference(s)

The Journal of Organic Chemistry, 48, p. 2424, 1983 DOI: 10.1021/jo00162a028

Boc-5-aminopentanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-5-aminopentanoic acid Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24539
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44751
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35906
Advantage
56
GL Biochem (Shanghai) Ltd
Tel
21-61263452 13641803416
Fax
86-21-61263399
Email
ymbetter@glbiochem.com
Country
China
ProdList
9981
Advantage
64
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11660
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
17940
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696;
Email
info@hanhongsci.com
Country
China
ProdList
42982
Advantage
64
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
15421
Advantage
60
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12990
Advantage
57
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View Lastest Price from Boc-5-aminopentanoic acid manufacturers

Career Henan Chemical Co
Product
Boc-5-aminopentanoic acid 27219-07-4
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-07

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