EC 1.1.1.42
- Product Name
- EC 1.1.1.42
- CAS No.
- 9028-48-2
- Chemical Name
- EC 1.1.1.42
- Synonyms
- IDH;ICDH;IDH1;MGC55806;MGC171441;MGC174090;EC 1.1.1.42;EC 1.1.1.42 TYPE I;EC 1.1.1.42 TYPE IV;:THREO-DS-ISOCITRATE
- CBNumber
- CB8395171
- Molecular Formula
- NULL
- Formula Weight
- 0
- MOL File
- Mol file
EC 1.1.1.42 Property
- storage temp.
- 2-8°C
- form
- solution (clear)
- color
- yellow-brown
Safety
- WGK Germany
- 3
- F
- 10
- HS Code
- 3507909090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- I5036
- Product name
- Isocitrate Dehydrogenase 1 (NADP+) human
- Purity
- recombinant, expressed in E. coli, lyophilized powder, ≥80?units/mg protein
- Packaging
- 100μg
- Price
- $517
- Updated
- 2024/03/01
- Product number
- I2411
- Product name
- Isocitrate Dehydrogenase 1 (NADP+) human
- Purity
- recombinant, expressed in Sf9 cells, ≥90% (SDS-PAGE)
- Packaging
- 10μg
- Price
- $717
- Updated
- 2024/03/01
- Product number
- I1877
- Product name
- Isocitric Dehydrogenase (NADP) from porcine heart
- Purity
- Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)
- Packaging
- 500mg
- Price
- $130.8
- Updated
- 2024/03/01
- Product number
- I1877
- Product name
- Isocitric Dehydrogenase (NADP) from porcine heart
- Purity
- Type I, 0.5-3.0 unit/mg solid (plus numerous enzyme activities associated with porcine heart)
- Packaging
- 1g
- Price
- $393
- Updated
- 2024/03/01
- Product number
- I2002
- Product name
- Isocitric Dehydrogenase (NADP) from porcine heart
- Purity
- Type IV, buffered aqueous glycerol solution, 3-20 units/mg protein
- Packaging
- 25mg
- Price
- $112
- Updated
- 2024/03/01
EC 1.1.1.42 Chemical Properties,Usage,Production
Uses
Human Isocitrate Dehydrogenase (IDH1) is useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. It may be useful as a biomarker for diagnosis and prognosis prediction of non-small cell lung cancer .
General Description
Isocitrate dehydrogenase 1 (IDH1) gene is located on human chromosome 2q33. IDH1 is present in the cytoplasm and peroxisomes. It is expressed at high levels in the mammalian liver. IDH1 consists of a C-terminal tripeptide peroxisome, that targets the signal one sequence.
Biochem/physiol Actions
Isocitrate dehydrogenase 1 (IDH1) help in the oxidative carboxylation of isocitrate to α-ketoglutarate, that results in the formation of reduced nicotinamide adenine dinucleotide phosphate (NADPH). It participates in lipid metabolism and glucose sensing. Suppressing IDH1 in pancreatic islets affects the insulin secretion, induced by glucose and leads to increase in lactate production.
EC 1.1.1.42 Preparation Products And Raw materials
Raw materials
Preparation Products
EC 1.1.1.42 Suppliers
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View Lastest Price from EC 1.1.1.42 manufacturers
- Product
- EC 1.1.1.42 9028-48-2
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 95%-99%
- Supply Ability
- 1000kg
- Release date
- 2018-12-25