t-Boc-N-amido-PEG5-MS

Product Name: t-Boc-N-amido-PEG5-MS
CAS No.: 2128735-28-2
Chemical Name: t-Boc-N-amido-PEG5-MS
Synonyms: Boc-NH-PEG5-Ms;Boc-N-Amido-PEG5-Ms;t-Boc-N-amido-PEG5-MS;5,8,11,14,17-Pentaoxa-18-thia-2-azanonadecanoic acid, 1,1-dimethylethyl ester, 18,18-dioxide
CBNumber: CB84680271
Molecular Formula: C16H33NO9S
Formula Weight: 415.5
MOL File: 2128735-28-2.mol

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t-Boc-N-amido-PEG5-MS Property

Boiling point:: 542.5±50.0 °C(Predicted)
Density: 1.161±0.06 g/cm3(Predicted)
pka: 12.23±0.46(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23788
Product name: t-Boc-N-Amido-PEG5-Ms
Purity: 98%
Packaging: 250mg
Price: $480
Updated: 2021/12/16

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t-Boc-N-amido-PEG5-MS Chemical Properties,Usage,Production

Description

t-Boc-N-Amido-PEG5-Ms is a PEG linker that contains a Boc protecting group and a mesyl group. The t-Boc group can be removed under acidic conditions to produce a reactive free amine. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of the compound. Longer PEG chains increase the water solubility properties of the compound.

Uses

Boc-N-Amido-PEG5-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

t-Boc-N-amido-PEG5-MS Preparation Products And Raw materials

Raw materials

Preparation Products

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t-Boc-N-amido-PEG5-MS Suppliers

China 22 United States 1 Global 23

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View Lastest Price from t-Boc-N-amido-PEG5-MS manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Boc-NH-PEG5-Ms 2128735-28-2
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-25

2128735-28-2, t-Boc-N-amido-PEG5-MSRelated Search:

t-Boc-N-Amido-PEG4-propargyl 2,2-DIMETHYL-4-OXO-3,8,11,14-TETRAOXA-5-AZAHEXADECAN-16-OIC ACID Boc-NH-PEG7-CH2CH2COOH 22-Amino-5,8,11,14,17,20-hexaoxa-2-azadocosanoic acid 1,1-dimethylethyl ester t-boc-N-amido-PEG5-azide t-Boc-N-amido-PEG5-acid Thiol-dPEG4-t-boc-N-amido t-Boc-N-Amido-PEG7-propargyl t-Boc-N-amido-PEG4-(CH2)3CO2H t-Boc-N-amido-PEG5-NHS ester t-Boc-N-Amido-PEG3-propargyl t-Boc-N-Amido-PEG6-Propargyl t-Boc-N-Amido-PEG4-Ms Boc-N-amido-PEG3-sulfonic acid 5,8,11-Trioxa-2-azatridecanoic acid, 13-[[(4-methylphenyl)sulfonyl]oxy]-, 1,1-dimethylethyl ester t-Boc-N-Amido-PEG5-propargyl t-Boc-N-Amido-PEG8-propargyl

t-Boc-N-amido-PEG5-MS

Boc-N-Amido-PEG5-Ms

Boc-NH-PEG5-Ms

5,8,11,14,17-Pentaoxa-18-thia-2-azanonadecanoic acid, 1,1-dimethylethyl ester, 18,18-dioxide

2128735-28-2