3-Bromo-2-(bromomethyl)propionic acid

Product Name: 3-Bromo-2-(bromomethyl)propionic acid
CAS No.: 41459-42-1
Chemical Name: 3-Bromo-2-(bromomethyl)propionic acid
Synonyms: 3-Bromo-2-(bromomethyl);3-Bromo-2-(bromomethyl)pr;β,β'-dibromoisobutyric acid;bis(bromomethyl)acetic acid;3-Bromo-2-Bromomethyl Propionate;BETA,BETA'-DIBROMOISOBUTYRIC ACID;3-BROMO-2-(BROMOMETHYL)PROPIONIC ACID;3-BROMO-2-(BROMOMETHYL)PROPANOIC ACID;Propanoic acid, 3-bromo-2-(bromomethyl)-;3-Bromo-2-(bromomethyl)propionic acid 97%
CBNumber: CB8780427
Molecular Formula: C4H6Br2O2
Formula Weight: 245.9
MOL File: 41459-42-1.mol

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3-Bromo-2-(bromomethyl)propionic acid Property

Melting point:: 98-101 °C(lit.)
Boiling point:: 286.7±30.0 °C(Predicted)
Density: 2.121±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Soluble in acetic acid.
form: Crystalline Powder
pka: 3.33±0.11(Predicted)
color: Off-white to brown
BRN: 1752505
InChI: InChI=1S/C4H6Br2O2/c5-1-3(2-6)4(7)8/h3H,1-2H2,(H,7,8)
InChIKey: QQZJWQCLWOQDQV-UHFFFAOYSA-N
SMILES: C(O)(=O)C(CBr)CBr
CAS DataBase Reference: 41459-42-1(CAS DataBase Reference)
NIST Chemistry Reference: Propionic acid, 3-bromo-2-(bromomethyl)-(41459-42-1)

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Safety

Hazard Codes: C
Risk Statements: 34
Safety Statements: 26-36/37/39-45
RIDADR: UN 3261 8/PG 2
WGK Germany: 3
F: 8
HazardClass: 8
PackingGroup: III
HS Code: 29159000
Storage Class: 8A - Combustible corrosive hazardous materials
Hazard Classifications: Skin Corr. 1B

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P363Wash contaminated clothing before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 301620
Product name: 3-Bromo-2-(bromomethyl)propionic acid
Purity: 97%
Packaging: 5g
Price: $78.3
Updated: 2023/06/20

TCI Chemical

Product number: B3081
Product name: 3-Bromo-2-(bromomethyl)propionic Acid
Purity: >98.0%(T)
Packaging: 5g
Price: $56
Updated: 2025/07/31

TCI Chemical

Product number: B3081
Product name: 3-Bromo-2-(bromomethyl)propionic Acid
Purity: >98.0%(T)
Packaging: 25g
Price: $216
Updated: 2025/07/31

TRC

Product number: B874120
Product name: 3-Bromo-2-(bromomethyl)propionic acid
Packaging: 1g
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 094009
Product name: 3-Bromo-2-(bromomethyl)propionic acid
Packaging: 5g
Price: $45
Updated: 2021/12/16

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3-Bromo-2-(bromomethyl)propionic acid Chemical Properties,Usage,Production

Chemical Properties

off-white to brown crystalline powder

Uses

3-Bromo-2-(bromomethyl)propionic acid acts as an organic building block for the preparation of beta-substituted acrylates. It is used in the preparation of t-butyl 2-(phenylthiomethyl) propenoate, t-butyl 3-(phenylthio)-2-(phenylthiomethyl)propenoate and 3-(phenylthio)-2-(phenyl-sulfinylmethyl)propenoate. Further, it plays an important role in the synthesis of beta-lactams by cyclization of the corresponding amide.

General Description

3-Bromo-2-(bromomethyl)propionic acid reacts with alkaline arsenite to yield (RS)-3-arsono-2-(hydroxymethyl)propionic acid.

Synthesis

A mixture of commercially available diethyl bis(hydroxymethyl)malonate (25 g., 0.11 mol.) and a 48% aqueous hydrogen bromide solution (192 cm3, 1.70 mol) was heated until the ethyl bromide liquid began to evaporate from the mixture and then vigorously distilled for about 1 h. The reaction mixture was refluxed at 140??C for 5 hours. The solution is cooled in an ice bath for 1. 5 hours. The crystals formed were filtered, washed with a small amount of ice-cold water and dried under vacuum. About 80 cm3 was distilled out of the of the filtrate, the solution was cooled in ice to produce another batch of crystals, washed and dried as before to give 3-bromo-2-bromomethylpropionic acid.

3-Bromo-2-(bromomethyl)propionic acid Preparation Products And Raw materials

Raw materials

Potassium bicarbonate Sodium sulfate Toluene Formaldehyde Hydrogen bromide Diethyl ether Nitric acid Diethyl malonate Diisopropyl ether Ammonium sulfate Sulfuric acid

Preparation Products

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3-Bromo-2-(bromomethyl)propionic acid Suppliers

Americas 1 Belgium 1 Canada 1 China 97 Europe 1 Germany 2 India 18 Japan 3 Poland 1 Switzerland 1 United Kingdom 10 United States 25 Global 161

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View Lastest Price from 3-Bromo-2-(bromomethyl)propionic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Bromo-2-(bromomethyl)propionic acid 41459-42-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-Bromo-2-(bromomethyl)propionic acid 41459-42-1
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-09

Career Henan Chemical Co

Product: 3-Bromo-2-(bromomethyl)propionic acid 41459-42-1
Price: US $9.80/KG
Min. Order: 1g
Purity: ≥99%
Supply Ability: 100kg
Release date: 2020-01-08

41459-42-1, 3-Bromo-2-(bromomethyl)propionic acidRelated Search:

Ethyl 2-(Chlorosulfonyl)acetate 4-Bromomethylbenzoic acid Bromotrimethylsilane Folic acid Propionic acid 1,3-Dimethylbarbituric acid 2-Bromopropionic acid 2,2-Bis(hydroxymethyl)propionic acid Citric acid Ascoric Acid Phenylacetic acid 3-Bromo-2-(bromomethyl)-propionic acid methyl ester 3-Bromopropionic acid 3-BROMO-2-METHYLPROPIONIC ACID 1-Bromo-2-methylpropane Methyl bromide (R)-(-)-3-BROMO-2-METHYL-1-PROPANOL Bromine

3-BROMO-2-(BROMOMETHYL)PROPANOIC ACID

3-BROMO-2-(BROMOMETHYL)PROPIONIC ACID

Propanoic acid, 3-bromo-2-(bromomethyl)-

BETA,BETA'-DIBROMOISOBUTYRIC ACID

bis(bromomethyl)acetic acid

β,β'-dibromoisobutyric acid

3-BROMO-2-(BROMOMETHYL)PROPIONIC ACID (KG LEVEL)

3-Bromo-2-(bromomethyl)propionic acid ,98%

3-BroMo-2-(broMoMethyl)propionic acid, 97% 1GR

3-BROMO-2-(BROMOMETHYL)PROPIONIC ACID, 9 7%

beta,beta'-Dibromoisobutyric Acid Bis(bromomethyl)acetic Acid

3-Bromo-2-(bromomethyl)propionic acid, Bis(bromomethyl)acetic acid

3-Bromo-2-(bromomethyl)propionic acid 97%

3-Bromo-2-(bromomethyl)

3-Bromo-2-(bromomethyl)propionic Acid &gt

3-Bromo-2-Bromomethyl Propionate

3-Bromo-2-(bromomethyl)pr

41459-42-1

C4H6Br2O2

BrCH22CHCO2H

Organic Building Blocks

C1 to C5

Carboxylic Acids

Carbonyl Compounds

Building Blocks

C1 to C5

Carbonyl Compounds

Carboxylic Acids

Chemical Synthesis

Organic Building Blocks