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Uridine-5'-triphosphoric acid trisodium salt

Product Name
Uridine-5'-triphosphoric acid trisodium salt
CAS No.
19817-92-6
Chemical Name
Uridine-5'-triphosphoric acid trisodium salt
Synonyms
Diquafosol Impurity 5;UTP.2Na;utp na3;5'-UTP 3Na;UTP Na3，UTP;Utipina Hydrate;UTP, TrisodiuM S;NSC 20260 Hydrate;UTP-Na3，5‘-UTP-Na3;UTP, 100mM Solution
CBNumber
CB8853286
Molecular Formula
C9H16N2NaO15P3
Formula Weight
508.14
MOL File
19817-92-6.mol
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Uridine-5'-triphosphoric acid trisodium salt Property

Melting point:
140 °C
Flash point:
113 °C
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
solubility 
H2O: soluble25 mg of UTP in 0.5 ml of solvent, clear, colorless
form 
Powder
color 
White
Water Solubility 
75 g/100 mL (20 ºC)
BRN 
3585234
InChI
InChI=1/C9H15N2O15P3.Na.H/c12-5-1-2-11(9(15)10-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H,10,12,15)(H2,16,17,18);;/t4-,6-,7-,8-;;/s3
InChIKey
IKVGSWYKOMJBSB-RFFBCSJBNA-N
SMILES
O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=CC(=O)NC1=O)O.[NaH] |&1:1,2,3,19,r|
CAS DataBase Reference
19817-92-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
20/21/22-68/20/21/22-68-36/37/38
Safety Statements 
22-26-36-36/37-24/25
WGK Germany 
1
RTECS 
YU8083000
HS Code 
29349990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
U6625
Product name
Uridine 5′-triphosphate trisodium salt hydrate
Purity
from yeast, Type III, ≥96%
Packaging
25mg
Price
$36.1
Updated
2024/03/01
Sigma-Aldrich
Product number
U6625
Product name
Uridine 5′-triphosphate trisodium salt hydrate
Purity
from yeast, Type III, ≥96%
Packaging
1g
Price
$669
Updated
2024/03/01
TCI Chemical
Product number
U0022
Product name
Uridine 5'-Triphosphate Trisodium Salt Hydrate
Purity
>95.0%(HPLC)
Packaging
100mg
Price
$43
Updated
2021/12/16
Alfa Aesar
Product number
J23160
Product name
Uridine-5'-triphosphate trisodium salt hydrate, 90+%
Purity
Thermo Scientific
Packaging
100mg
Price
$45.5
Updated
2021/12/16
Alfa Aesar
Product number
J23160
Product name
Uridine-5'-triphosphate trisodium salt hydrate, 90+%
Purity
Thermo Scientific
Packaging
1g
Price
$224.97
Updated
2021/12/16
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Uridine-5'-triphosphoric acid trisodium salt Chemical Properties,Usage,Production

Description

Uridine-5'-triphosphoric acid trisodium salt, also known as UTP, is a polyphosphate analogue of uridine that is used in the synthesis of agonists at the G-protein-coupled P2Y receptors.

Chemical Properties

White crystalline powder

Uses

psychostimulant

Uses

P2Y receptor agonist.

Uses

Uridine-5'-triphosphoric acid trisodium salt is a polyphosphate analogue of the nucleoside uridine used in the preparation of potent and selective agonists at the G-protein-coupled P2Y receptors.

Application

Uridine-5'-triphosphoric acid trisodium salt solution can be used to increase intracellular Ca2+ levels in rat primary tracheal epithelial cells. It is also used as a nucleotide substrate to analyze the activity of MutT homolog 1 (MTH1).

Biochem/physiol Actions

Uridine-5′-Triphosphate?(UTP) is a cytosolic nucleotide component of nucleic acids. It serves as a signaling molecule in the extracellular space. Uridine-5′-Triphosphate?(UTP) is involved in various pathophysiological responses in the nervous system.?UTP also plays a major role in the regeneration process.

in vitro

Uridine triphosphate (UTP) (0, 10, 100, 250, 500, and 1000 μM; 2, 4, 6, 8, 10, and 12 h) trisodium salt enhances RT4-D6P2T cells migration and wound repair. Uridine triphosphate trisodium salt induces Schwannoma cell migration through the activation of P2Y2 receptors and the increase of extracellular MMP-2 activation and expression. Uridine triphosphate (UTP) trisodium salt (Uridine-5'-triphosphoric acid trisodium salt) evokes MAPK phosphorylation in a biphasic pattern MAPK phosphorylation, with an early transient phosphorylation 5 min after treatment and a late and sustained phosphorylation that appeared at 6 h and lasted up to 24 h.

Uridine-5'-triphosphoric acid trisodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Uridine-5'-triphosphoric acid trisodium salt manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Price
US $10.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 ton
Release date
2024-12-20
Watson Biotechnology Co.,Ltd
Product
Uridine-5'-triphosphoric acid trisodium salt 19817-92-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000kg
Release date
2024-09-05
HangZhou RunYan Pharma Technology Co.,LTD.
Product
Uridine 5’-triphosphate trisodium salt； UTP-Na3，5‘-UTP-Na3 19817-92-6
Price
US $0.00/kg
Min. Order
1kg
Purity
95.0%min. HPLC
Supply Ability
10000kg
Release date
2022-11-07

19817-92-6, Uridine-5'-triphosphoric acid trisodium saltRelated Search:

Sodium citrate EPA Sodium phosphate tribasic dodecahydrate URIDINE-13C9, 15N2-5 TRIPHOSPHATE SODI U Cytidine 5'-triphosphate disodium salt UTP 1-beta-D-Arabinofuranosyluracil Trisodium phosphate ATP disodium salt Guanosine-5'-triphosphoric aicd disodium salt Uridine-5'-diphosphate disodium salt UMP UDPGA TRISODIUM SALT URIDINE 5'-TRIPHOSPHATE TRISODIUM SALT DMT-2′O-TBDMS-rU Phosphoramidite Uridine 5'-diphosphoglucose disodium salt Adenosine5'-(tetrahydrogen triphosphate), disodiuM salt, trihydrate (9CI) Diquafosol

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