Pyridoxine hydrochloride
Nutrition supplements- Product Name
- Pyridoxine hydrochloride
- CAS No.
- 58-56-0
- Chemical Name
- Pyridoxine hydrochloride
- Synonyms
- Pyridoxine hydrochloride (Vitamin B6);campoviton6;5-Hydroxy-6-methyl-3,4-pyridinedimethanol;pyridox;paxadon;becilan;benadon;hexobion;hexermin;aderoxin
- CBNumber
- CB8853882
- Molecular Formula
- C8H12ClNO3
- Formula Weight
- 205.64
- MOL File
- 58-56-0.mol
Pyridoxine hydrochloride Property
- Melting point:
- 214-215 °C(lit.)
- Density
- 1.2784 (rough estimate)
- vapor density
- 7.1 (vs air)
- refractive index
- 1.5800 (estimate)
- Flash point:
- 9℃
- storage temp.
- room temp
- solubility
- H2O: 0.1 g/mL at 20 °C, clear, colorless
- form
- Crystalline Powder
- color
- White to almost white
- PH Range
- 3.2
- Water Solubility
- 0.1 g/mL (20 ºC)
- Sensitive
- Light Sensitive
- Merck
- 14,7982
- BRN
- 3632435
- BCS Class
- 1
- Stability:
- Stable. Protect from air and light.
- LogP
- -1.098 (est)
- CAS DataBase Reference
- 58-56-0(CAS DataBase Reference)
- EPA Substance Registry System
- 5-Hydroxy-6-methyl-3,4-pyridinedimethanol, hydrochloride (58-56-0)
Safety
- Hazard Codes
- Xi,T,F
- Risk Statements
- 36/37/38-39/23/24/25-23/24/25-11
- Safety Statements
- 26-37/39-45-36/37-16-7-24/25
- RIDADR
- UN1230 - class 3 - PG 2 - Methanol, solution
- WGK Germany
- 2
- RTECS
- UV1350000
- F
- 8-10
- TSCA
- Yes
- HS Code
- 29362500
- Hazardous Substances Data
- 58-56-0(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H318Causes serious eye damage
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 80823
- Product name
- Pyridoxine hydrochloride
- Purity
- certified reference material, TraceCERT
- Packaging
- 50mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- 47862
- Product name
- Pyridoxine Hydrochloride (B6)
- Purity
- analytical standard
- Packaging
- 1000mg
- Price
- $23.2
- Updated
- 2024/03/01
- Product number
- 1587001
- Product name
- Pyridoxine hydrochloride
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 200mg
- Price
- $447
- Updated
- 2024/03/01
- Product number
- BP458
- Product name
- Pyridoxine hydrochloride
- Purity
- British Pharmacopoeia (BP) Reference Standard
- Packaging
- 100MG
- Price
- $221
- Updated
- 2023/06/20
- Product number
- P0561
- Product name
- Pyridoxine Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $44
- Updated
- 2024/03/01
Pyridoxine hydrochloride Chemical Properties,Usage,Production
Nutrition supplements
Chemical Properties
White or almost white, crystalline powder.
Uses
Pyridoxine Hydrochloride is an acid form of vitamin b6, a water- soluble vitamin. it is soluble in water, and slightly soluble in alco- hol. it is slowly affected by sunlight and is reasonably stable in air. it has a ph of 2.3–3.5. it is also termed vitamin b6 hydrochloride. see pyridoxine.
Application
Pyridoxine hydrochloride has been used:
As a vitamin component in a chemically defined diet with balanced metal content for metal depletion studies;
As a component of chemically defined medium (CDM) to culture Staphylococcus aureus WSPPA;
As analytical reference standards for the determination of analytes in pharmaceutical preparations by chromatography and spectrophotometric techniques;
As a vitamin to study the impact of protein expression and post-translational modifications specifically charge heterogeneity;
As a medicine, it is used to prevent or treat certain neurological disorders (peripheral neuropathy) caused by certain drugs (e.g. isoniazid). It is also used in the treatment of certain hereditary disorders (e.g. flavoururic aciduria, hyperoxaluria, homocystinuria).
Definition
ChEBI: Pyridoxine hydrochloride is the hydrochloride salt of pyridoxine. It is a hydrochloride and a vitamin B6. It contains a pyridoxine.
brand name
Hexa-Betalin (Lilly).
General Description
Vitamin B6 has six forms namely, pyridoxal, pyridoxine, pyridoxamine, pyridoxamine 5′-phosphate, pyridoxine 5′-phosphate and pyridoxal 5′-phosphate. Pyridoxine hydrochloride primarily treats vitamin B6 deficiency and helps alleviate nausea and vomiting during pregnancy. It exists in various forms, including pyridoxine, pyridoxal, and pyridoxamine, which convert into the active coenzyme pyridoxal 5-phosphate (PLP or P5P) in the body.
Biochem/physiol Actions
Vitamin B6 is an essential coenzyme for amino acid, carbohydrate and lipid metabolism. Pyridoxine serves as a primary source in multivitamins. Pyridoxine deficiency is associated with peripheral neuropathy.
Clinical Use
Vitamin B6
Side effects
Common side effects of Pyridoxine hydrochloride include: headache, nausea, drowsiness, mild numbness or tingling. Serious allergic reactions are rare and include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, difficulty breathing, decreased sensation of touch, temperature, and vibration; loss of balance or coordination. If serious side effects occur please seek medical attention.
Safety Profile
Poison by intravenous route. Moderately toxic by ingestion, intramuscular, and subcutaneous routes. Human reproductive effects by ingestion and intramuscular routes: postpartum changes. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Metabolism
Pyridoxine hydrochloride is metabolised to its active form pyridoxamine phosphate. It is stored mainly in the liver where there is oxidation to 4-pyridoxic acid and other inactive metabolites which are excreted in the urine.
Purification Methods
Purify the vitamin by recrystallisation from EtOH/Me2CO, n-BuOH or MeOH/Et2O. Its solubility in H2O is 22%, and in EtOH it is 1.1%. It is insoluble in Et2O and CHCl3. Acidic aqueous solutions are stable at 120o/30minute. The free base has m 159-160o after recrystallisation from Me2CO and sublimation at 140-145o/0.0001mm. It has UV max at 290nm ( 84,000), 253 and 325nm ( 3,700 and 7,100) in 0.1N aqueous HCl. [Khua & Wendt Chem Ber 71 780 1938, 72 311 1939, Harris & Folkers J Am Chem Soc 61 1242 1939, Harris et al. J Am Chem Soc 62 3198 1940, Beilstein 21/5 V 492.]
Pyridoxine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
Pyridoxine hydrochloride Suppliers
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View Lastest Price from Pyridoxine hydrochloride manufacturers
- Product
- Vitamin B6 58-56-0
- Price
- US $0.00-0.00/Kg/Bag
- Min. Order
- 1Kg/Bag
- Purity
- 99% up, High Density
- Supply Ability
- 20 tons
- Release date
- 2024-06-27
- Product
- Pyridoxine hydrochloride 58-56-0
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-11-28
- Product
- Pyridoxine hydrochloride 58-56-0
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 0.98
- Supply Ability
- 1000
- Release date
- 2024-06-03