Pranoprofen
- Product Name
- Pranoprofen
- CAS No.
- 52549-17-4
- Chemical Name
- Pranoprofen
- Synonyms
- 2-(5H-Chromeno[2,3-b]pyridin-7-yl)propanoic acid;Niflan;Y 8004;Cesflan;Oftalar;ranoprofen;PRANOPROFEN;pyranoprofen;dl-Pranoprofen;(RS)-Pranoprofen
- CBNumber
- CB9189564
- Molecular Formula
- C15H13NO3
- Formula Weight
- 255.27
- MOL File
- 52549-17-4.mol
Pranoprofen Property
- Melting point:
- 182-183°
- Boiling point:
- 398.5°C (rough estimate)
- Density
- 1.1654 (rough estimate)
- refractive index
- 1.5500 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 4.27±0.10(Predicted)
- form
- powder
- color
- white to beige
- CAS DataBase Reference
- 52549-17-4(CAS DataBase Reference)
Safety
- RIDADR
- UN 2811 6.1 / PGIII
- RTECS
- DJ3100950
- Toxicity
- LD50 in male mice, rats (mg/kg): 447.3, 87.3 orally (Edanaga)
N-Bromosuccinimide Price
- Product number
- SML1423
- Product name
- Pranoprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 50mg
- Price
- $38.9
- Updated
- 2024/03/01
- Product number
- SML1423
- Product name
- Pranoprofen
- Purity
- ≥98% (HPLC)
- Packaging
- 250mg
- Price
- $115
- Updated
- 2024/03/01
- Product number
- 17875
- Product name
- Pranoprofen
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $32
- Updated
- 2024/03/01
- Product number
- 17875
- Product name
- Pranoprofen
- Purity
- ≥98%
- Packaging
- 1g
- Price
- $359
- Updated
- 2024/03/01
- Product number
- 17875
- Product name
- Pranoprofen
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $61
- Updated
- 2024/03/01
Pranoprofen Chemical Properties,Usage,Production
Chemical Properties
Off-White Solid
Originator
Niflan, Yoshitomi ,Japan ,1981
Uses
Pranoprofen is an anti-inflammatory used in ophthalmology.
Definition
ChEBI: Pranoprofen is a pyridochromene.
Manufacturing Process
A mixture of 100 g of ethyl 2-cyano-2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionate, 500 ml of glacial acetic acid and 200 g of concentrated hydrochloric acid is refluxed for 48 hours. The reaction mixture is concentrated, and the residue is dissolved in hot water. The solution is adjusted to pH 2 to 3 by addition of 10% sodium hydroxide. The resulting crystalline precipitate is washed thoroughly with water, and recrystallized from aqueous dioxane to give 74 g of 2-(5H-[1]benzopyrano[2,3-b]-pyridin-7yl)propionic acid as white crystals melting at 183°C to 183.5°C.
Therapeutic Function
Analgesic, Antiinflammatory
General Description
Pranoprofen is an arylalkanoic acid and a non-steroidal anti-inflammatory drug.
Biochem/physiol Actions
Pranoprofen is used in eyes to treat chronic allergic conjunctivitis. It is also used as an anti-inflammatory and analgesic drug after strabismus surgery.
Pranoprofen Preparation Products And Raw materials
Raw materials
Preparation Products
Pranoprofen Suppliers
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View Lastest Price from Pranoprofen manufacturers
- Product
- Pranoprofen 52549-17-4
- Price
- US $15.00/kg
- Min. Order
- 1kg
- Purity
- 99.912%
- Supply Ability
- 10ton
- Release date
- 2024-04-25
- Product
- Pranoprofen 52549-17-4
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 90%+
- Supply Ability
- 10g
- Release date
- 2021-09-17
- Product
- Pranoprofen 52549-17-4
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 20 tons
- Release date
- 2024-04-07