ChemicalBook > CAS DataBase List > 4-BROMO-2,5-DIFLUOROANILINE

4-BROMO-2,5-DIFLUOROANILINE

Product Name: 4-BROMO-2,5-DIFLUOROANILINE
CAS No.: 112279-60-4
Chemical Name: 4-BROMO-2,5-DIFLUOROANILINE
Synonyms: 4-BROMO-2,5-DIFLUOROANILINE;2,5-Difluoro-4-bromoaniline;4-Bromo-2,5-difluoroaniline98%;4-Bromo-2,5-difluoroaniline >4-broMo-2,5-difluorobenzenaMine;4-Bromo-2,5-difluoroaniline 98%;4-Bromo-2,5-difluoro-phenylamine;Benzenamine, 4-bromo-2,5-difluoro-;4-BROMO-2,5-DIFLUOROANILINE ISO 9001：2015 REACH;4-bromo-2,5-difluorophenylamine,4-BroMo-2,5-difluoroaniline,4-Amino-2,5-difluorobromobenzene,4-Bromo-2,5-difluorobenzenamine
CBNumber: CB9242885
Molecular Formula: C6H4BrF2N
Formula Weight: 208
MOL File: 112279-60-4.mol

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4-BROMO-2,5-DIFLUOROANILINE Property

Melting point:: 74-78 °C (lit.)
Boiling point:: 212.1±35.0 °C(Predicted)
Density: 1.788±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: powder to crystal
pka: 1.48±0.10(Predicted)
color: White to Light yellow
BRN: 4741102
InChI: InChI=1S/C6H4BrF2N/c7-3-1-5(9)6(10)2-4(3)8/h1-2H,10H2
InChIKey: XOYHFIQPPOJMFK-UHFFFAOYSA-N
SMILES: C1(N)=CC(F)=C(Br)C=C1F
CAS DataBase Reference: 112279-60-4(CAS DataBase Reference)

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Safety

Hazard Codes: T,Xi
Risk Statements: 25-36/37/38
Safety Statements: 28-45
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29214200

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 638412
Product name: 4-Bromo-2,5-difluoroaniline
Purity: 97%
Packaging: 5g
Price: $64.3
Updated: 2025/07/31

Sigma-Aldrich

Product number: 638412
Product name: 4-Bromo-2,5-difluoroaniline
Purity: 97%
Packaging: 1g
Price: $35
Updated: 2023/06/20

TCI Chemical

Product number: B2072
Product name: 4-Bromo-2,5-difluoroaniline
Purity: >98.0%(GC)
Packaging: 1g
Price: $23
Updated: 2025/07/31

TCI Chemical

Product number: B2072
Product name: 4-Bromo-2,5-difluoroaniline
Purity: >98.0%(GC)
Packaging: 5g
Price: $64
Updated: 2025/07/31

TRC

Product number: B699578
Product name: 4-Bromo-2,5-difluoroaniline
Packaging: 10mg
Price: $45
Updated: 2021/12/16

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4-BROMO-2,5-DIFLUOROANILINE Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

367-30-6

112279-60-4

Example 14 Preparation of 4-bromo-2,5-difluoroaniline: To a stirred mixture of 100 g of 2,5-difluoroaniline and 1150 mL of acetic acid (AcOH) was slowly added 40.2 mL of bromine (Br2) in 350 mL of acetic acid (AcOH) over a period of 1.3 h. The reaction temperature was maintained at a temperature of between 15 °C and 20 °C. The reaction was carried out over a period of 2.3 hours. Upon completion of the reaction, the resulting pink suspension was continued to be stirred for 30 minutes, followed by vacuum evaporation to remove the solvent. The residue was alkalized with 50% sodium hydroxide (NaOH) solution (ice was added during the process to maintain the temperature below 35°C). The free base was extracted with 1 L of dichloromethane (CH2Cl2), and the extract was washed with 2 x 100 mL of water (H2O), dried over anhydrous sodium sulfate (Na2SO4), and finally the solvent was evaporated under vacuum to afford 157 g (97.5% yield) of the target product 4-bromo-2,5-difluoroaniline, with melting points ranging from 73°C to 75°C. Mass spectrometry analysis showed the M+1 ion peaks at 208 and 210.

References

[1] Patent: EP224001, 1991, B1
[2] Molecular Crystals and Liquid Crystals (1969-1991), 1991, vol. 204, p. 43 - 64
[3] Journal of Materials Chemistry, 2004, vol. 14, # 11, p. 1731 - 1743
[4] Patent: EP329752, 1989, A1
[5] Patent: WO2013/142266, 2013, A1. Location in patent: Paragraph 00498

4-BROMO-2,5-DIFLUOROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-BROMO-2,5-DIFLUOROANILINE manufacturers

HANGZHOU HAILAN CHEMICAL CO.,LTD.

Product: 4-BROMO-2,5-DIFLUOROANILINE 112279-60-4
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%min
Supply Ability: 20tons
Release date: 2025-08-26

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-BROMO-2,5-DIFLUOROANILINE 112279-60-4
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-28

Career Henan Chemical Co

Product: 4-BROMO-2,5-DIFLUOROANILINE 112279-60-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100kg
Release date: 2019-07-11

112279-60-4, 4-BROMO-2,5-DIFLUOROANILINERelated Search:

5-BROMO-2,4-DIFLUOROANILINE,3-BROMO-4,6-DIFLUOROANILINE 4-BROMO-2,5-DIFLUOROANILINE 4-BROMO-3,5-DIFLUOROANILINE,4-Bromo-3,5-difluoroaniline 95% 2-Bromo-3,4-Difluoroaniline 2-BROMO-4,6-DIFLUOROANILINE,2-Bromo-4,6-difluoroaniline, 99+%,2-Bromo-4,6-difluoroaniline98%,2-Bromo-4,6-difluoroaniline 98%,6-BROMO-2,4-DIFLUOROANILINE 4-BROMO-2,6-DIFLUOROANILINE,4-BROMO-2,6-DIFLUOROANILINE 99% 4-BROMO-2,5-DIFLUORONITROBENZENE 3-Bromo-4,5-difluoroaniline 98%,3-Bromo-4,5-difluoroaniline98%,3-BROMO-4,5-DIFLUOROANILINE 2,5-Difluoroaniline 3-Bromo-2,6-difluoroaniline 2,4-Dibromo-3,6-difluoroaniline 4-Bromo-2,5-difluorophenylisothiocyanate 4-BROMOTETRAFLUOROPHENYLHYDRAZINE 4-BROMO-2,3,5,6-TETRAFLUOROANILINE 3-Bromo-2,4-difluoroaniline 5-BROMO-2,3-DIFLUOROANILINE 4-Bromo-2,3-difluoroaniline 2-BROMO-4,5-DIFLUOROANILINE

4-BROMO-2,5-DIFLUOROANILINE

4-Bromo-2,5-difluoroaniline 98%

4-Bromo-2,5-difluoroaniline98%

4-Bromo-2,5-difluoro-phenylamine

2,5-Difluoro-4-bromoaniline

4-broMo-2,5-difluorobenzenaMine

4-Bromo-2,5-difluoroaniline &gt

Benzenamine, 4-bromo-2,5-difluoro-

4-BROMO-2,5-DIFLUOROANILINE ISO 9001：2015 REACH

4-bromo-2,5-difluorophenylamine,4-BroMo-2,5-difluoroaniline,4-Amino-2,5-difluorobromobenzene,4-Bromo-2,5-difluorobenzenamine

112279-60-4

279-60-4

112279-06-4

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