Amino-PEG4-acid

ChemicalBook > CAS DataBase List > Amino-PEG4-acid

Product Name: Amino-PEG4-acid
CAS No.: 663921-15-1
Chemical Name: Amino-PEG4-acid
Synonyms: 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid;NH2-PEG4-COOH;Amino-PEG4-acid;NH2-PEG4-CH2CH2COOH;3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid;NH2-PEG4-PA;AMINE-PEG4-COOH;Amino-PEG4-COOH;amino-dPEG4-acid;Amino-dPEGx-acid
CBNumber: CB92501434
Molecular Formula: C11H23NO6
Formula Weight: 265.3
MOL File: 663921-15-1.mol

Less

Amino-PEG4-acid Property

Boiling point:: 409.6±40.0 °C(Predicted)
Density: 1.134±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.28±0.10(Predicted)
form: powder
color: White
InChI: InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
InChIKey: DKUZHSDZSMQOGQ-UHFFFAOYSA-N
SMILES: C(O)(=O)CCOCCOCCOCCOCCN

Less

Safety

HS Code: 2942000090

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: QBD10244
Product name: Amino-dPEG®4-acid
Purity: >95% (HPLC)
Packaging: 100MG
Price: $170
Updated: 2024/03/01

TRC

Product number: H289595
Product name: H2N-Dpeg(4)-COOH
Packaging: 100mg
Price: $110
Updated: 2021/12/16

BroadPharm

Product number: BP-20423
Product name: Amino-PEG4-acid
Purity: 98%
Packaging: 1g
Price: $320
Updated: 2021/12/16

dPEG

Product number: 10244
Product name: Amino-dPEG®₄-acid
Packaging: 1000mg
Price: $350
Updated: 2021/12/16

Activate Scientific

Product number: AS114327
Product name: H2N-PEG4-CH2CH2COOH
Purity: 97+%
Packaging: 1g
Price: $398
Updated: 2021/12/16

Less

Amino-PEG4-acid Chemical Properties,Usage,Production

Description

Amino-PEG4-acid is a very popular PEG linker. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond, long PEG spacer increases reagent's solubility in aqueous media.

Uses

H2N-Dpeg(4)-COOH, can be used in optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers. Integrin αvβ3 plays great roles in tumor angiogenesis, invasion, and metastasis.

benefits

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 ?) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (D = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.

References

1. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. DOI:10.1021/mp800150r
2. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. DOI:10.1021/bc400050k
3. Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. DOI:10.1021/bc100013b
4. Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers. DOI:10.1021/bc800455p

Amino-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

Less

Amino-PEG4-acid Suppliers

China 116 India 1 United Kingdom 1 United States 14 Global 132

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6637
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 10002
Advantage: 58

Xi‘an Deeptech Biotechnology Co.,LTD

Tel: 15114901355
Email: 15114901355@163.com
Country: China
ProdList: 183
Advantage: 58

PharmaBlock Sciences (Nanjing),Inc.

Tel: 400-0255188 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44700
Advantage: 61

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3296
Advantage: 57

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6874
Advantage: 65

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: +8613162137806 18575662672
Fax: 021 51613951
Email: mzeng@3wpharm.com
Country: China
ProdList: 9743
Advantage: 57

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498 19102685862
Fax: 086-28-82550468
Email: sales@pu-kang.com
Country: China
ProdList: 485
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9900
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 13901585132
Fax: +86-25-52131256
Email: 799750417@qq.com
Country: China
ProdList: 8888
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18216
Advantage: 56

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25014
Advantage: 65

Nanjing Anyan Pharmaceutical Technology Co. , Ltd.

Tel: 025-5836128; 18136859766
Fax: QQ3209878052
Email: amy.xiang@ally-chem.com
Country: China
ProdList: 357
Advantage: 60

Hygeia (Chengdu) pharmaceutical technique Co., Ltd

Tel: 028-84502008 13568869383
Fax: 028-66476329
Email: sales@hygeiapharm.com
Country: China
ProdList: 295
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-1647117 15221909166
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41438
Advantage: 60

Chongqing Xingcan Pharmaceutical Technology Co., Ltd.

Tel: 15523000485
Email: xingcanyaoye@sina.com
Country: China
ProdList: 1686
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10287
Advantage: 55

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4115
Advantage: 58

Shanghai Boka-chem Tech. Inc.

Tel: 400-026-1533/(021) 6478-0600
Fax: +86 (21) 6459-2060
Email: sales@bokachem.com
Country: China
ProdList: 876
Advantage: 58

Tongling HengYou Biotechnology Co., Ltd.

Tel: 021-50426030 13856289449
Fax: 021-50426030
Email: 2630597085@qq.com
Country: China
ProdList: 1889
Advantage: 55

Alta Scientific Co., Ltd.

Tel: 022-6537-8550 15522853686
Fax: 022-2532-9655
Email: sales@altasci.com.cn
Country: China
ProdList: 4515
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1246
Advantage: 55

Shanghai TuZhi Chemical Co., Ltd.

Tel: 19542790274; 19542790274
Fax: QQ1456295541
Email: 1456295541@qq.com
Country: China
ProdList: 832
Advantage: 50

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 9859
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131980
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28821
Advantage: 58

Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd

Tel: +86-021-50929289 86186163093
Fax: -
Email: sales@ypptech.com.cn
Country: China
ProdList: 344
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 0571-86101219 13675881727
Fax: -
Email: sales@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

Aikon International Limited

Tel: 025-66028182 18112977050
Fax: (3)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 15820
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4824
Advantage: 58

Shanghai He Huan Chemical Co., Ltd.

Tel: 021-60345187 13917602471
Fax: 021-60345187
Email: lzz841106@aliyun.com
Country: China
ProdList: 9907
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 18016230971
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 24971
Advantage: 58

Abydos Scientific

Tel: 025-84767922 18936879710
Email: sales@abydoscientific.com
Country: China
ProdList: 1018
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Ji'nan tengbang pharmaceutical science and Technology Co., Ltd.

Tel: 0531-88769236 15688889648
Email: 2685550793@qq.com
Country: China
ProdList: 122
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

Shanghai Akasaka Biotechnology Co., Ltd.

Tel: 15121162054
Country: CHINA
ProdList: 635
Advantage: 58

Henan Alfa Chemical Co., Ltd

Tel: +8618339805032
Email: alfa4@alfachem.cn
Country: China
ProdList: 13040
Advantage: 58

Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19915
Advantage: 58

Wuhan Borenpharm Co., Ltd

Tel: 027-65563561 18717150066
Fax: 027-59218822
Email: 3207347307@qq.com
Country: CHINA
ProdList: 1238
Advantage: 58

Chengdu Pukang Biotechnology Co., Ltd

Tel: 028-82550498
Email: export@pu-kang.com
Country: CHINA
ProdList: 210
Advantage: 58

JenKem Technology Co., Ltd.

Tel: 010-62983737 18612451121
Email: sales@jenkem.com
Country: China
ProdList: 101
Advantage: 58

Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

Tel: 029-86217788 13892832556
Email: 2440688701@qq.com
Country: China
ProdList: 1992
Advantage: 58

Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
Country: CHINA
ProdList: 7651
Advantage: 58

Suzhou Derivative Biotechnology Co., Ltd.

Tel: 13915541704
Email: 2436368162@qq.com
Country: China
ProdList: 304
Advantage: 58

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: 021-58955996
Email: info@chemexpress.com
Country: China
ProdList: 706
Advantage: 58

Less

View Lastest Price from Amino-PEG4-acid manufacturers

airuikechemical co., ltd.

Product: α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Xian confluore Biological Technology Co., Ltd.

Product: Amino-PEG4-COOH 663921-15-1
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-22

Career Henan Chemical Co

Product: α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

663921-15-1, Amino-PEG4-acidRelated Search:

Azido-PEG2-CH2CO2tBu Amino-PEG24-acid FMoc-NH-8(ethylene glycol)-acetic acid Amino-PEG2-acid PENTAETHYLENE GLYCOL 3,6,9,12-tetraoxatridecylamine alpha-Azido-omega-hydroxy octa(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID alpha, oMega-Dipropionic acid hexaethylene glycol (R)-N-(3,6,9,12-Tetraoxatridecyl)-alpha-lipoamide Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL α,ω-dipropionic acid tetraethylene glycol Amino-PEG25-t-butly ester Azido-PEG4-Acyl Chloride Azido-PEG10-S-methyl ethanethioate Amino-PEG3-t-butly acetate

3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid

1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid

Α-AMINE-Ω-PROPIONIC ACID TETRAETHYLENE GLYCOL

Amino-PEG4-acid

α-amine-ω-propionic acid tetraethylene glycol

alpha-aMine-oMega-propionic acid tetraethylene glycol

H2N-PEG4-CH2CH2COOH

Amino-dPEGx-acid

amino-dPEG4-acid

Amino-PEG4-propionic acid

AMINE-PEG4-COOH

NH2-PEG4-COOH

Amino-PEG4-COOH

3-Amino(peg4)propionic acid

3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid

1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic Acid

NH2-PEG4-CH2CH2COOH

α-Amine-ω-propionic acid tetraethylene glycol,Amino-PEG4-acid

Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-

3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid

α-Amine-ω-propionic acid tetraethylene glycol hydrochloride

α-Amine-ω-propionic acid tetraethylene glycol

H2N-PEG4-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-

NH2-PEG4-PA

663921-15-1

C11H23NO6

PEG-COOH

peg