ChemicalBook > CAS DataBase List > Amino-PEG4-acid

Amino-PEG4-acid

Product Name
Amino-PEG4-acid
CAS No.
663921-15-1
Chemical Name
Amino-PEG4-acid
Synonyms
1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid;NH2-PEG4-COOH;Amino-PEG4-acid;NH2-PEG4-CH2CH2COOH;3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid;NH2-PEG4-PA;AMINE-PEG4-COOH;Amino-PEG4-COOH;amino-dPEG4-acid;Amino-dPEGx-acid
CBNumber
CB92501434
Molecular Formula
C11H23NO6
Formula Weight
265.3
MOL File
663921-15-1.mol
More
Less

Amino-PEG4-acid Property

Boiling point:
409.6±40.0 °C(Predicted)
Density 
1.134±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
4.28±0.10(Predicted)
form 
powder
color 
White
InChI
InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
InChIKey
DKUZHSDZSMQOGQ-UHFFFAOYSA-N
SMILES
C(O)(=O)CCOCCOCCOCCOCCN
More
Less

Safety

HS Code 
2942000090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
QBD10244
Product name
Amino-dPEG®4-acid
Purity
>95% (HPLC)
Packaging
100MG
Price
$170
Updated
2024/03/01
TRC
Product number
H289595
Product name
H2N-Dpeg(4)-COOH
Packaging
100mg
Price
$110
Updated
2021/12/16
BroadPharm
Product number
BP-20423
Product name
Amino-PEG4-acid
Purity
98%
Packaging
1g
Price
$320
Updated
2021/12/16
dPEG
Product number
10244
Product name
Amino-dPEG®₄-acid
Packaging
1000mg
Price
$350
Updated
2021/12/16
Activate Scientific
Product number
AS114327
Product name
H2N-PEG4-CH2CH2COOH
Purity
97+%
Packaging
1g
Price
$398
Updated
2021/12/16
More
Less

Amino-PEG4-acid Chemical Properties,Usage,Production

Description

Amino-PEG4-acid is a very popular PEG linker. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond, long PEG spacer increases reagent's solubility in aqueous media.

Uses

H2N-Dpeg(4)-COOH, can be used in optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers. Integrin αvβ3 plays great roles in tumor angiogenesis, invasion, and metastasis.

benefits

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 ?) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (D = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.

References

1. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. DOI:10.1021/mp800150r
2. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. DOI:10.1021/bc400050k
3. Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. DOI:10.1021/bc100013b
4. Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers. DOI:10.1021/bc800455p

Amino-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

Amino-PEG4-acid Suppliers

China 120 India 1 United Kingdom 1 United States 15 Global 137
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
6887
Advantage
58
Zhengzhou Convergence Chemical Co. LTD
Tel
0371-53736046 13393710386
Fax
QQ:2853979814
Email
2853979814@qq.com
Country
China
ProdList
9994
Advantage
58
Xi‘an Deeptech Biotechnology Co.,LTD
Tel
+86-15114901355 +86-15114901355
Email
15114901355@163.com
Country
China
ProdList
189
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
PharmaBlock Sciences (Nanjing),Inc.
Tel
025-86918202 4000255188
Fax
86-025-86918232
Email
sales@pharmablock.com
Country
China
ProdList
4986
Advantage
55
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Beijing Isomersyn Technology CO;LTD
Tel
010-82954736 13391601435
Email
sales@isomersyn.com
Country
China
ProdList
3295
Advantage
57
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7195
Advantage
65
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
021-51613915-820 13611835272
Fax
021 51613951
Email
mmwang@sunwaypharm.cn
Country
China
ProdList
9734
Advantage
57
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 19102685862
Fax
086-28-82550468
Email
sales@pu-kang.com
Country
China
ProdList
485
Advantage
58
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
13901585132
Fax
+86-25-52131256
Email
799750417@qq.com
Country
China
ProdList
8878
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
18209
Advantage
56
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-400-6206333 18521732826
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Nanjing Anyan Pharmaceutical Technology Co. , Ltd.
Tel
025-58361178 17351780683
Fax
QQ3209878052
Email
amy.xiang@ally-chem.com
Country
China
ProdList
356
Advantage
60
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Hygeia (Chengdu) pharmaceutical technique Co., Ltd
Tel
028-84502008 13568869383
Fax
028-66476329
Email
sales@hygeiapharm.com
Country
China
ProdList
299
Advantage
55
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41462
Advantage
60
Chongqing Xingcan Pharmaceutical Technology Co., Ltd.
Tel
15523000485
Email
xingcanyaoye@sina.com
Country
China
ProdList
1687
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10274
Advantage
55
Mashilabs (Shanghai) Co.,Ltd.
Tel
19916721580
Fax
QQ：3154870176
Email
mafarm@126.com
Country
China
ProdList
4301
Advantage
58
Shanghai Boka-chem Tech. Inc.
Tel
400-026-1533/(021) 6478-0600
Fax
+86 (21) 6459-2060
Email
sales@bokachem.com
Country
China
ProdList
876
Advantage
58
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Alta Scientific Co., Ltd.
Tel
022-6537-8550 15522853686
Fax
022-2532-9655
Email
sales@altasci.com.cn
Country
China
ProdList
4511
Advantage
55
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Shanghai TuZhi Chemical Co., Ltd.
Tel
19542790274 19542790274
Fax
QQ1456295541
Email
2119559397@qq.com
Country
China
ProdList
883
Advantage
50
Chengdu Dianchun Technology Co., Ltd
Tel
400-1166-196 18502815961
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
9996
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
Advantage
58
Yaopu(Shanghai) Pharmaceutical Technology Co., Ltd
Tel
021-50929289 86186163093
Fax
-
Email
sales@ypptech.com.cn
Country
China
ProdList
289
Advantage
58
Aikon International Limited
Tel
025-66028182 18112977050
Fax
(3)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
15818
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4825
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 18016230971
Fax
021-58955996
Email
malulu@leyan.com
Country
China
ProdList
25004
Advantage
58
Abydos Scientific
Tel
025-84767922 18936879710
Email
sales@abydoscientific.com
Country
China
ProdList
1009
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
4009004166/18616739031 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52693
Advantage
58
Ji'nan tengbang pharmaceutical science and Technology Co., Ltd.
Tel
0531-88769236 15688889648
Email
2685550793@qq.com
Country
China
ProdList
124
Advantage
58
Alpha Biopharmaceuticals Co., Ltd
Tel
0411-39042497
Fax
0411-39042693
Email
sales@alphabiopharm.com
Country
China
ProdList
1951
Advantage
58
Shanghai Akasaka Biotechnology Co., Ltd.
Tel
15121162054
Country
CHINA
ProdList
635
Advantage
58
Henan Alfa Chemical Co., Ltd
Tel
Country
China
ProdList
10947
Advantage
58
Nextpeptide Inc
Tel
+86-0571-81612335 +8613336028439
Email
sales@nextpeptide.com
Country
China
ProdList
19908
Advantage
58
Wuhan Borenpharm Co., Ltd
Tel
027-65563561 18717150066
Fax
027-59218822
Email
3207347307@qq.com
Country
CHINA
ProdList
1238
Advantage
58
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498
Email
export@pu-kang.com
Country
CHINA
ProdList
210
Advantage
58
JenKem Technology Co., Ltd.
Tel
010-62983737 18612451121
Email
sales@jenkem.com
Country
China
ProdList
107
Advantage
58
Shaanxi Xinyan Bomei Biotechnology Co., Ltd.
Tel
029-86217788 13892832556
Email
2440688701@qq.com
Country
China
ProdList
1992
Advantage
58
Shanghai Jiange Chemical Co., Ltd.
Tel
15921040873
Email
1434142450@qq.com
Country
CHINA
ProdList
7649
Advantage
58
Suzhou Derivative Biotechnology Co., Ltd.
Tel
13915541704
Email
2436368162@qq.com
Country
China
ProdList
310
Advantage
58
More
Less

View Lastest Price from Amino-PEG4-acid manufacturers

airuikechemical co., ltd.
Product
α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price
US $0.00-0.00/Kg
Min. Order
1Kg
Purity
99.9%
Supply Ability
200tons
Release date
2024-04-08
Xian confluore Biological Technology Co., Ltd.
Product
Amino-PEG4-COOH 663921-15-1
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-22
Career Henan Chemical Co
Product
α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price
US $8.80/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
100kg
Release date
2019-07-04

663921-15-1, Amino-PEG4-acidRelated Search:

Azido-PEG2-CH2CO2tBu Amino-PEG24-acid FMoc-NH-8(ethylene glycol)-acetic acid Amino-PEG2-acid PENTAETHYLENE GLYCOL 3,6,9,12-tetraoxatridecylamine alpha-Azido-omega-hydroxy octa(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID alpha, oMega-Dipropionic acid hexaethylene glycol (R)-N-(3,6,9,12-Tetraoxatridecyl)-alpha-lipoamide Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL α,ω-dipropionic acid tetraethylene glycol Amino-PEG25-t-butly ester Azido-PEG4-Acyl Chloride Azido-PEG10-S-methyl ethanethioate Amino-PEG3-t-butly acetate

  • 3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid
  • 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid
  • Α-AMINE-Ω-PROPIONIC ACID TETRAETHYLENE GLYCOL
  • Amino-PEG4-acid
  • α-amine-ω-propionic acid tetraethylene glycol
  • alpha-aMine-oMega-propionic acid tetraethylene glycol
  • H2N-PEG4-CH2CH2COOH
  • Amino-dPEGx-acid
  • amino-dPEG4-acid
  • Amino-PEG4-propionic acid
  • AMINE-PEG4-COOH
  • NH2-PEG4-COOH
  • Amino-PEG4-COOH
  • 3-Amino(peg4)propionic acid
  • 3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid
  • 1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic Acid
  • NH2-PEG4-CH2CH2COOH
  • α-Amine-ω-propionic acid tetraethylene glycol,Amino-PEG4-acid
  • Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
  • 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid
  • α-Amine-ω-propionic acid tetraethylene glycol hydrochloride
  • α-Amine-ω-propionic acid tetraethylene glycol
  • H2N-PEG4-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-
  • NH2-PEG4-PA
  • 663921-15-1
  • C11H23NO6
  • PEG-COOH
  • peg