Amino-PEG4-acid

Product Name: Amino-PEG4-acid
CAS No.: 663921-15-1
Chemical Name: Amino-PEG4-acid
Synonyms: 1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid;NH2-PEG4-COOH;Amino-PEG4-acid;NH2-PEG4-CH2CH2COOH;3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid;NH2-PEG4-PA;AMINE-PEG4-COOH;Amino-PEG4-COOH;amino-dPEG4-acid;Amino-dPEGx-acid
CBNumber: CB92501434
Molecular Formula: C11H23NO6
Formula Weight: 265.3
MOL File: 663921-15-1.mol

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Amino-PEG4-acid Property

Boiling point:: 409.6±40.0 °C(Predicted)
Density: 1.134±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 4.28±0.10(Predicted)
form: powder
color: White
InChI: InChI=1S/C11H23NO6/c12-2-4-16-6-8-18-10-9-17-7-5-15-3-1-11(13)14/h1-10,12H2,(H,13,14)
InChIKey: DKUZHSDZSMQOGQ-UHFFFAOYSA-N
SMILES: C(O)(=O)CCOCCOCCOCCOCCN

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Safety

HS Code: 2942000090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: QBD10244
Product name: Amino-dPEG®4-acid
Purity: >95% (HPLC)
Packaging: 100MG
Price: $170
Updated: 2024/03/01

TRC

Product number: H289595
Product name: H2N-Dpeg(4)-COOH
Packaging: 100mg
Price: $110
Updated: 2021/12/16

BroadPharm

Product number: BP-20423
Product name: Amino-PEG4-acid
Purity: 98%
Packaging: 1g
Price: $320
Updated: 2021/12/16

dPEG

Product number: 10244
Product name: Amino-dPEG®₄-acid
Packaging: 1000mg
Price: $350
Updated: 2021/12/16

Activate Scientific

Product number: AS114327
Product name: H2N-PEG4-CH2CH2COOH
Purity: 97+%
Packaging: 1g
Price: $398
Updated: 2021/12/16

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Amino-PEG4-acid Chemical Properties,Usage,Production

Description

Amino-PEG4-acid is a very popular PEG linker. The amino group (NH2) is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The terminal carboxylic acid can react with primary amine groups of activated NHS ester to form a stable amide bond, long PEG spacer increases reagent's solubility in aqueous media.

Uses

H2N-Dpeg(4)-COOH, can be used in optical imaging of integrin αvβ3 expression with near-infrared fluorescent RGD dimer with tetra(ethylene glycol) linkers. Integrin αvβ3 plays great roles in tumor angiogenesis, invasion, and metastasis.

benefits

Amino-dPEG4-acid has a primary amine and propionic acid terminating opposite ends of a 16-atoms long (18.0 ?) polyethylene glycol (PEG) spacer. The single molecular weight PEG spacer is discrete (D = 1). Moreover, it is highly hydrophilic, and it imparts hydrophilicity to conjugates that incorporate it. Amino-dPEG4-acid is useful in many different applications, including peptide synthesis, surface modification, dendrimer construction, and small molecule modification.

References

1. Improving tumor-targeting capability and pharmacokinetics of (99m)Tc-labeled cyclic RGD dimers with PEG(4) linkers. DOI:10.1021/mp800150r
2. Short PEG-linkers improve the performance of targeted, activatable monoclonal antibody-indocyanine green optical imaging probes. DOI:10.1021/bc400050k
3. Microwave-mediated synthesis of labeled nucleotides with utility in the synthesis of DNA probes. DOI:10.1021/bc100013b
4. Improving tumor uptake and pharmacokinetics of (64)Cu-labeled cyclic RGD peptide dimers with Gly(3) and PEG(4) linkers. DOI:10.1021/bc800455p

Amino-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Amino-PEG4-acid Suppliers

China 120 India 1 United Kingdom 1 United States 15 Global 137

Wuhan Augda Biotechnology Co., Ltd

Tel: 15071299552
Fax: QQ:262933239
Email: 262933239@qq.com
Country: China
ProdList: 6887
Advantage: 58

Zhengzhou Convergence Chemical Co. LTD

Tel: 0371-53736046 13393710386
Fax: QQ:2853979814
Email: 2853979814@qq.com
Country: China
ProdList: 9990
Advantage: 58

Xi‘an Deeptech Biotechnology Co.,LTD

Tel: +86-15114901355 +86-15114901355
Email: 15114901355@163.com
Country: China
ProdList: 189
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

PharmaBlock Sciences (Nanjing),Inc.

Tel: 025-86918202 4000255188
Fax: 86-025-86918232
Email: sales@pharmablock.com
Country: China
ProdList: 4986
Advantage: 55

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44688
Advantage: 61

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 7195
Advantage: 65

ChemPep, Inc.

Tel: +1 (888) 615-9178 / (561) 791-8787
Fax: +1 (561) 791-8728
Email: service@chempep.com
Country: United States
ProdList: 2138
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 021-51613915-820 13611835272
Fax: 021 51613951
Email: mmwang@sunwaypharm.cn
Country: China
ProdList: 9734
Advantage: 57

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View Lastest Price from Amino-PEG4-acid manufacturers

airuikechemical co., ltd.

Product: α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price: US $0.00-0.00/Kg
Min. Order: 1Kg
Purity: 99.9%
Supply Ability: 200tons
Release date: 2024-04-08

Xian confluore Biological Technology Co., Ltd.

Product: Amino-PEG4-COOH 663921-15-1
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 25g
Release date: 2024-03-22

Career Henan Chemical Co

Product: α-amine-ω-propionic acid tetraethylene glycol 663921-15-1
Price: US $8.80/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 100kg
Release date: 2019-07-04

663921-15-1, Amino-PEG4-acidRelated Search:

Azido-PEG2-CH2CO2tBu Amino-PEG24-acid FMoc-NH-8(ethylene glycol)-acetic acid Amino-PEG2-acid PENTAETHYLENE GLYCOL 3,6,9,12-tetraoxatridecylamine alpha-Azido-omega-hydroxy octa(ethylene glycol) FMOC-18-AMINO-4,7,10,13,16-PENTAOXAOCTADECANOIC ACID alpha, oMega-Dipropionic acid hexaethylene glycol (R)-N-(3,6,9,12-Tetraoxatridecyl)-alpha-lipoamide Z-15-aMino-4,7,10,13-tetraoxapentadecacanoic acid N-BIOTINYL-3,6-DIOXAOCTANE-1,8-DIAMINE O-(2-AMINOETHYL)-O-(2-(BOC-AMINO)ETHYL)OCTAETHYLENE GLYCOL α,ω-dipropionic acid tetraethylene glycol Amino-PEG25-t-butly ester Azido-PEG4-Acyl Chloride Azido-PEG10-S-methyl ethanethioate Amino-PEG3-t-butly acetate

3-[2-[2-[2-(2-Aminoethoxy)ethoxy]ethoxy]ethoxy]propionic acid

1-AMino-3,6,9,12-tetraoxapentadecan-15-oic acid

Α-AMINE-Ω-PROPIONIC ACID TETRAETHYLENE GLYCOL

Amino-PEG4-acid

α-amine-ω-propionic acid tetraethylene glycol

alpha-aMine-oMega-propionic acid tetraethylene glycol

H2N-PEG4-CH2CH2COOH

Amino-dPEGx-acid

amino-dPEG4-acid

Amino-PEG4-propionic acid

AMINE-PEG4-COOH

NH2-PEG4-COOH

Amino-PEG4-COOH

3-Amino(peg4)propionic acid

3-[2-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)ethoxy]propanoic acid

1-Amino-3,6,9,12-tetraoxa-15-pentadecanoic Acid

NH2-PEG4-CH2CH2COOH

α-Amine-ω-propionic acid tetraethylene glycol,Amino-PEG4-acid

Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-

3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]propanoic acid

α-Amine-ω-propionic acid tetraethylene glycol hydrochloride

α-Amine-ω-propionic acid tetraethylene glycol

H2N-PEG4-CH2CH2COOH/Propanoic acid, 3-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]-

NH2-PEG4-PA

663921-15-1

C11H23NO6

PEG-COOH

peg