METHYL 4-AMINO-3-NITROBENZOATE

Product Name: METHYL 4-AMINO-3-NITROBENZOATE
CAS No.: 3987-92-6
Chemical Name: METHYL 4-AMINO-3-NITROBENZOATE
Synonyms: 4-AMINO-3-NITROMETHYLBENZOATE;METHYL 4-AMINO-3-NITROBENZOATE;Methyl 3-nitro-4-aminobenzoate;Methyl4-amino-3-nitrobenzoate,97%;METHYL 4-AMINO-3-NITROBENZENECARBOXYLATE;4-Amino-3-nitrobenzoic acid methyl ester;3-Nitro-4-aminobenzoic acid methyl ester;Benzoic acid, 4-amino-3-nitro-, methyl ester;methyl 4-amino-3-nitrobenzoatemethyl 4-amino-3-nitrobenzoate;2-Amino-5-(methoxycarbonyl)nitrobenzene, 4-(Methoxycarbonyl)-2-nitroaniline
CBNumber: CB9282610
Molecular Formula: C8H8N2O4
Formula Weight: 196.16
MOL File: 3987-92-6.mol

More

Less

METHYL 4-AMINO-3-NITROBENZOATE Property

Melting point:: 204-206°C
Boiling point:: 392.8±22.0 °C(Predicted)
Density: 1.386±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
pka: -2.59±0.10(Predicted)
Appearance: Light yellow to yellow Solid

More

Less

Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2922390090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M328673
Product name: Methyl4-amino-3-nitrobenzoate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M328673
Product name: Methyl4-amino-3-nitrobenzoate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 042844
Product name: Methyl 4-amino-3-nitrobenzenecarboxylate
Purity: 95+%
Packaging: 1g
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: OR15213
Product name: Methyl4-amino-3-nitrobenzoate
Packaging: 5g
Price: $27
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4658-1-Z3
Product name: Methyl 4-amino-3-nitrobenzoate
Packaging: 5G
Price: $29
Updated: 2021/12/16

More

Less

METHYL 4-AMINO-3-NITROBENZOATE Chemical Properties,Usage,Production

Chemical Properties

Methyl 4-amino-3-nitrobenzoate is a synthetic compound that has been found to have a variety of uses. It has been used to prepare intramolecular hydrogen bonds in anilines, and it can be used as an intermediate to synthesize amides and anilines. This molecule also forms resonance structures with the nitro group, which allows for increased stability. The proton magnetic resonance spectra of Methyl 4-amino-3-nitrobenzoate show that the molecule has a high degree of symmetry, which is due to the presence of intramolecular hydrogen bonding.

Synthesis

67-56-1

1588-83-6

3987-92-6

4-Amino-3-nitrobenzoic acid (50 g, 270 mmol, 1 eq.) was suspended in methanol (600 mL) at room temperature. Subsequently, sulfoxide chloride (20 mL, 270 mmol, 1 eq.) was slowly added dropwise to the above suspension. The reaction mixture was heated to reflux for 16 h. After completion of the reaction, it was cooled to room temperature. The resulting yellow solid, methyl 4-amino-3-nitrobenzoate (D1) (53 g, 100% yield), was collected by filtration, and the product could be used in subsequent reactions without further purification. Mass spectrometry analysis showed [M + H]+ = 197.3, retention time (RT) = 2.42 min.

References

[1] Patent: WO2004/94430, 2004, A1. Location in patent: Page 16
[2] Patent: WO2006/40148, 2006, A1. Location in patent: Page/Page column 19-20
[3] Patent: WO2015/57938, 2015, A1. Location in patent: Page/Page column 102
[4] Patent: CN106146416, 2016, A. Location in patent: Paragraph 0046; 0047; 0048; 0049; 0050
[5] European Journal of Medicinal Chemistry, 2018, vol. 143, p. 8 - 20

METHYL 4-AMINO-3-NITROBENZOATE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

METHYL 4-AMINO-3-NITROBENZOATE Suppliers

China 118 Europe 1 France 1 India 6 Ukraine 1 United Kingdom 7 United States 13 Global 147

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
ProdList: 11035
Advantage: 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

Beijing Eternalchem Co,. Ltd.

Tel: 010-59484199 18611897322
Email: sales@eternalchem.com
Country: China
ProdList: 4383
Advantage: 60

China Langchem Inc.

Tel: 0086-21-58956006
Fax: 0086-21-58956100
Country: China
ProdList: 7811
Advantage: 57

Aemon Chemical

Tel: 0086-755-86198205
Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

Wuhan Haizheng Industry & Trade Development Co. Ltd

Tel: 027-8866 0053/88660577/88660578
Fax: 027-8899 1911
Country: China
ProdList: 1073
Advantage: 55

More

Less

View Lastest Price from METHYL 4-AMINO-3-NITROBENZOATE manufacturers

Asia Chem I and E (Jiangsu) Co Ltd

Product: Methyl 4-amino-3-nitrobenzoate 3987-92-6
Price: US $100.00/kg
Min. Order: 1kg
Purity: 98.0%min
Supply Ability: 20tons/month
Release date: 2024-12-30

Career Henan Chemical Co

Product: Methyl 4-amino-3-nitrobenzoate 3987-92-6
Price: US $7.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2018-12-25

3987-92-6, METHYL 4-AMINO-3-NITROBENZOATERelated Search:

Methyl 4-aMino-2,6-diMethylbenzoate Methyl 4-amino-3-bromobenzoate Methyl 2,6-dichloro-4-aminobenzoate Methyl 4-amino-3-(trifluoromethoxy)benzoate METHYL 4-AMINO-3-CHLOROBENZOATE METHYL 4-AMINO-2,3-DIFLUORO-5-NITROBENZOATE METHYL 4-AMINO-2,3-DIFLUOROBENZOATE METHYL 4-AMINO-3-CHLORO-5-METHYLBENZOATE Methyl-4-amino-3-fluorobenzoate Methyl 4-amino-2-chlorobenzoate Methyl 4-aMino-3,5-difluorobenzoate Methyl 4-amino-2-cyanobenzoate Methyl 4-amino-2-methoxybenzoate METHYL 4-AMINO-3,5-DICHLOROBENZOATE methyl 4-amino-2-chloro-5-iodobenzoate methyl 4-amino-2-bromo-3-fluorobenzoate Methyl-4-amino-3-bromo-5-methylbenzoate Methyl 4-amino-3-methoxybenzoate

4-AMINO-3-NITROMETHYLBENZOATE

3-Nitro-4-aminobenzoic acid methyl ester

4-Amino-3-nitrobenzoic acid methyl ester

METHYL 4-AMINO-3-NITROBENZENECARBOXYLATE

METHYL 4-AMINO-3-NITROBENZOATE

methyl 4-amino-3-nitrobenzoatemethyl 4-amino-3-nitrobenzoate

Methyl 3-nitro-4-aminobenzoate

2-Amino-5-(methoxycarbonyl)nitrobenzene, 4-(Methoxycarbonyl)-2-nitroaniline

Benzoic acid, 4-amino-3-nitro-, methyl ester

Methyl4-amino-3-nitrobenzoate,97%

3987-92-6

Aromatic Esters