Azido-PEG3-Sulfone-PEG4-acid

Product Name: Azido-PEG3-Sulfone-PEG4-acid
CAS No.: 2055024-42-3
Chemical Name: Azido-PEG3-Sulfone-PEG4-acid
Synonyms: Azido-PEG3-Sulfone-PEG4-acid;4,7,10,13,19,22,25-Heptoxa-16-thiaheptacosanoic acid, 27-azido-, 16,16-dioxide
CBNumber: CB93162872
Molecular Formula: C19H37N3O11S
Formula Weight: 515.58
MOL File: 2055024-42-3.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23236
Product name: Azido-PEG3-Sulfone-PEG4-acid
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23236
Product name: Azido-PEG3-Sulfone-PEG4-acid
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

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Azido-PEG3-Sulfone-PEG4-acid Chemical Properties,Usage,Production

Description

Azido-PEG3-Sulfone-PEG4-acid is a PEG linker containing one azide group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) forming a stable amide bond. The azide group enables Click Chemistry. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-Sulfone-PEG4-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG3-Sulfone-PEG4-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG3-Sulfone-PEG4-acid Suppliers

China 16 United States 2 Global 18

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

Aladdin Scientific

Tel
Email: tp@aladdinsci.com
Country: United States
ProdList: 52923
Advantage: 58

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View Lastest Price from Azido-PEG3-Sulfone-PEG4-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG3-Sulfone-PEG4-acid 2055024-42-3
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2055024-42-3, Azido-PEG3-Sulfone-PEG4-acidRelated Search:

Bromo-PEG3-azide Azide-PEG3-Sulfone-PEG3-Azide Azido-PEG3-NHS ester Azide-PEG3-Tos 1,11-DIAZIDO-3,6,9-TRIOXAUNDECANE 2-[2-(2-AZIDOETHOXY)ETHOXY]ETHANOL N3-PEG3-Hydrazide 11-AZIDO-3 6 9-TRIOXAUNDECAN-1-AMINE Azido-PEG3-Sulfone-PEG4-t-butyl ester Azido-dPEG4-acid N3-PEG3-tBu

Azido-PEG3-Sulfone-PEG4-acid

4,7,10,13,19,22,25-Heptoxa-16-thiaheptacosanoic acid, 27-azido-, 16,16-dioxide

2055024-42-3