(R)-(-)-Glycidyl nosylate

Product Name: (R)-(-)-Glycidyl nosylate
CAS No.: 115314-17-5
Chemical Name: (R)-(-)-Glycidyl nosylate
Synonyms: Landiolol Impurity 1;Landiolol impurity78;(R)-GLYCIDYL NOSYLATE;Landiolol Impurity 73;(R)-Glycidil-4-Nosylate;(R)-(-)-GLYCIDYL NOSYLATE;(R)-(-)-GLYCIDYL-3-NOSYLATE;(R)-Glycidyl Nosylate,99%e.e.;(R)-(-)-Glycidyl nosylate,98%;R-Glycidyl-3-Nitrobenzenesulfo
CBNumber: CB9329397
Molecular Formula: C9H9NO6S
Formula Weight: 259.24
MOL File: 115314-17-5.mol

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(R)-(-)-Glycidyl nosylate Property

Melting point:: 59-63 °C
alpha: -21.5 º (c=2, CHCl3)
Boiling point:: 432.2±20.0 °C(Predicted)
Density: 1.5881 (rough estimate)
refractive index: 1.5270 (estimate)
storage temp.: Inert atmosphere,2-8°C
solubility: Chloroform (Slightly), DMSO (Slightly)
form: Crystalline Needles or Powder
color: Slightly yellow
optical activity: -22.001°(C=1.00 g/100ml, CHCL3)
InChI: InChI=1S/C9H9NO6S/c11-10(12)7-2-1-3-9(4-7)17(13,14)16-6-8-5-15-8/h1-4,8H,5-6H2/t8-/m1/s1
InChIKey: AIHIHVZYAAMDPM-MRVPVSSYSA-N
SMILES: C1(S(OC[C@H]2CO2)(=O)=O)=CC=CC([N+]([O-])=O)=C1
CAS DataBase Reference: 115314-17-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 37/39-26-36
RIDADR: UN 1325 4.1/PG II
RTECS: DB7192000
HazardClass: 4.1
PackingGroup: II
HS Code: 29209090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H228Flammable solid

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P308+P313IF exposed or concerned: Get medical advice/attention.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: G0286
Product name: (R)-Glycidyl 3-Nitrobenzenesulfonate
Purity: >98.0%(GC)
Packaging: 5g
Price: $53
Updated: 2025/07/31

TCI Chemical

Product number: G0286
Product name: (R)-Glycidyl 3-Nitrobenzenesulfonate
Purity: >98.0%(GC)
Packaging: 25g
Price: $178
Updated: 2025/07/31

TRC

Product number: G615975
Product name: (R)-(-)-GlycidylNosylate
Packaging: 5g
Price: $45
Updated: 2021/12/16

SynQuest Laboratories

Product number: 8664-1-R0
Product name: (R)-Glycidyl nosylate
Purity: 97%
Packaging: 5G
Price: $48
Updated: 2021/12/16

Chem-Impex

Product number: 39554
Product name: (R)-Glycidyl3-nitrobenzenesulfonate,≥98%(GC)Hazmat
Purity: ≥98%(GC)
Packaging: 5G
Price: $51.25
Updated: 2021/12/16

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(R)-(-)-Glycidyl nosylate Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powde

Uses

(R)-(-)-Glycidyl Nosylate (cas# 115314-17-5) is a compound useful in organic synthesis.

Synthesis

121-51-7

60456-23-7

115314-14-2

Preparation of Compound 3: To an anhydrous dichloromethane (10 mL) and triethylamine (1.5 mL, 10 mmol) solution of (S)-oxiran-2-ylmethanol (220 mg, 3.0 mmol) that had been cooled to 0 °C (ice bath), 3-nitrobenzenesulfonyl chloride (730 mg, 3.3 mmol) was added in batches. The resulting brown solution was stirred at 0 °C for 1 h, followed by slow warming to room temperature. The progress of the reaction was monitored by TLC every 15 min until (S)-oxiran-2-ylmethanol was completely consumed. Upon completion of the reaction, the reaction was quenched by the addition of crushed ice (1-2 g). The reaction mixture was transferred to a dispensing funnel and partitioned with dichloromethane (20 mL) and water (10 mL). The organic layer was washed sequentially with saturated aqueous NaHCO3 (10 mL x 3) and brine (10 mL x 3), followed by drying with anhydrous Na2SO4. After filtration and concentration, the residue was purified by fast column chromatography to afford (S)-(+)-m-nitrobenzenesulfonic acid glycidyl ester (Compound 3) as a brown solid (710 mg, 92%).1H NMR (400 MHz, CDCl3) δ 8.77 (s, 1H), 8.54 (d, J=8.1 Hz, 1H), 8.28 (d, J=7.9 Hz , 1H), 4.50 (d, J=11.5Hz, 1H), 4.04 (dd, J1=4.9Hz, J2=1.5Hz, 1H), 3.23 (d, J=1.8Hz, 1H), 2.85 (dd, J1=4.0Hz, J2=2.0Hz, 1H), 2.64 (dd, J1=2.4Hz, J2=2.0Hz, 1H) 1H); 13C NMR (100 MHz, CDCl3) δ 148.19, 137.92, 133.32, 130.81, 128.39, 123.16, 71.69, 48.64, 44.42.

References

[1] Patent: US2009/182011, 2009, A1. Location in patent: Page/Page column 13
[2] ACS Medicinal Chemistry Letters, 2011, vol. 2, # 9, p. 656 - 661
[3] Tetrahedron, 2009, vol. 65, # 31, p. 5984 - 5989
[4] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 8, p. 2948 - 2950
[5] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 17, p. 4792 - 4802

(R)-(-)-Glycidyl nosylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(R)-(-)-Glycidyl nosylate Suppliers

Americas 1 Belgium 3 Canada 2 China 156 Europe 3 France 1 Germany 3 India 10 Japan 7 South Korea 1 Switzerland 1 United Kingdom 14 United States 46 Global 248

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View Lastest Price from (R)-(-)-Glycidyl nosylate manufacturers

Henan Fengda Chemical Co., Ltd

Product: (R)-(-)-Glycidyl nosylate 115314-17-5
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-25

Shaanxi Dideu Medichem Co. Ltd

Product: (R)-(-)-Glycidyl nosylate 115314-17-5
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100 tons
Release date: 2020-01-10

Career Henan Chemical Co

Product: (R)-(-)-Glycidyl nosylate 115314-17-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2019-12-26

115314-17-5, (R)-(-)-Glycidyl nosylateRelated Search:

Glycidyl acrylate Sodium 3-nitrobenzenesulphonate Methanol ETHYLENE OXIDE Monostearin Glycidyl tertcarbonate 3-NITROBENZENESULFONIC ACID 4-Nitrophenyl chloroformate (R)-Glycidyl butyrate 2,4,6-TRINITROBENZENESULFONIC ACID 3-Nitrobenzenesulfonyl chloride Nitrobenzene (S)-(-)-Propylene oxide (S)-Oxiranemethanol 2-METHOXYMETHYL METHANSULFONATE (S)-GLYCIDYL NOSYLATE,(S)-(+)-GLYCIDYL NOSYLATE Benzenesulfonic acid (R)-(+)-Glycidol

(R)-Glycidyl Nosylate,99%e.e.

3-nitro-,oxiranylmethylester,(r)-benzenesulfonicaci

oxiranylmethyl(r)-3-nitrobenzenesulfonate

(R)-(-)-OXIRANE-2-METHANOL 3-NITROBENZENESULFONATE

(R)-(-)-GLYCIDYL NOSYLATE

(R)-GLYCIDYL NOSYLATE

(R)-(-)-GLYCIDYL-3-NITROBENZENESULFONATE

(R) glycidyl nosylate = (R)-oxiran-2-ylmethyl 3-nitrobenzenesulfonate

Landiolol Impurity 1

(R)-GLYCIDYL 3-NITROBENZENESULFONATE

(R)-(-)-GLYCIDYL-3-NOSYLATE

(R)-2,3-EPOXY-1-PROPYL-3-NITROBENZENESULFONATE

BENZENESULFONIC ACID, 3-NITRO-, (2R)-OXIRANYLMETHYL ESTER

3-NITROBENZENESULFONIC ACID (R)-GLYCIDYL ESTER

(2R)-(-)-GLYCIDYL-3-NITROBENZENESULFONATE

(2R)-(-)-Glycidyl-3-nitrobenzenesulphonate

(2R)-(-)-GLYCIDYL 3-NITROBENZENE-

(R)-(-)-Glycidyl 3-nitrobenzenesulfonate, (R)-(-)-Oxirane-2-methanol 3-nitrobenzenesulfonate

[(2R)-Oxiran-2-yl]methyl 3-nitrobenzenesulfonate

Benzenesulfonic acid, 3-nitro-, oxiranylmethyl ester, (R)

(R)-(-)-Glycidyl nosylate,98%

R-Glycidyl-3-Nitrobenzenesulfo

(R)-(-)-GLYCIDYL3-NITRO-BENZENESULPHONATE

BENZENESULFONIC ACID, 3-NITRO-(2R)-2-OXIRANYL-METHYL ESTER

(R)-Glycidil-4-Nosylate

(R)-Oxiran-2-ylMethyl 3-nitrobenzenesulfonate

(2R)-OxiranylMethyl 3-Nitrobenzenesulfonate

(R)-Glycidol 3-Nitrobenzenesulfonate

(R)-Glycidyl3-Nitrobenzenesulfonate&gt

(R)-(-)-Glycidyl nosylate ISO 9001：2015 REACH

3-nitro-Benzenesulfonic acid (2R)-2-oxiranylmethyl ester

Landiolol Impurity 73

Landiolol impurity78

3-Nitro-benzenesulfonic acid (2R)-oxiran-2-ylmethyl ester

115314-17-5

C9H9NO6S1

Asymmetric Synthesis

Epoxides

Organic Building Blocks

Chiral Building Blocks

chiral

CHIRAL COMPOUNDS

Chiral Reagents

Heterocycles

Sulfur & Selenium Compounds