Neuraminidase

ChemicalBook > CAS DataBase List > Neuraminidase

Product Name: Neuraminidase
CAS No.: 9001-67-6
Chemical Name: Neuraminidase
Synonyms: SIALIDASE;EC 3.2.1.18;SIALIDASE L;IUB: 3.2.1.18;ALP Separator;NEURAMINIDASE;Neuraminidase B;Neuraminidase A;exo-α-sialidase;3) Neuraminidase
CBNumber: CB9348886
Molecular Formula: NULL
Formula Weight: 0
MOL File: Mol file

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Neuraminidase Property

Density: 1.00 g/mL at 20 °C
storage temp.: 2-8°C
form: lyophilized powder
color: white
Water Solubility: Soluble in water or 10mM phosphate buffer, pH 6.0
EPA Substance Registry System: Neuraminidase (9001-67-6)

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Safety

Safety Statements: 22-24/25
RIDADR: UN3373 - class 6.2 Biological substance, Category B
WGK Germany: 3
RTECS: QQ3450000
F: 3-10
TSCA: Yes

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H290May be corrosive to metals

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P234Keep only in original container.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N7885
Product name: Neuraminidase from Vibrio cholerae
Purity: Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
Packaging: 1unit
Price: $181
Updated: 2024/03/01

Sigma-Aldrich

Product number: N8271
Product name: α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens
Purity: recombinant, expressed in E. coli, buffered aqueous solution
Packaging: 0.2unit
Price: $638
Updated: 2024/03/01

Sigma-Aldrich

Product number: N7885
Product name: Neuraminidase from Vibrio cholerae
Purity: Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
Packaging: 2units
Price: $332
Updated: 2024/03/01

Sigma-Aldrich

Product number: N5631
Product name: Neuraminidase from Clostridium perfringens (C. welchii)
Purity: Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
Packaging: 1unit
Price: $69.2
Updated: 2024/03/01

Sigma-Aldrich

Product number: N5631
Product name: Neuraminidase from Clostridium perfringens (C. welchii)
Purity: Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
Packaging: 5units
Price: $226
Updated: 2024/03/01

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Neuraminidase Chemical Properties,Usage,Production

Uses

Neuraminidase is used as a hydrolytic enzyme that removes sialic acid from mucoproteins, used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase.

Uses

Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.

Uses

Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.

General Description

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

Biochem/physiol Actions

Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells.

Neuraminidase Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Neuraminidase manufacturers

Hubei Xindesheng Material Technology Co., Ltd.

Product: neuraminidase 9001-67-6
Price: US $42.00-38.80/KU
Min. Order: 10KU
Purity: ≥400U/mg
Supply Ability: 1000ku
Release date: 2020-11-04

Career Henan Chemical Co

Product: ACETYLNEURAMINYL HYDROLASE 9001-67-6
Price: US $2.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100kg
Release date: 2020-01-07

9001-67-6, NeuraminidaseRelated Search:

Ferric acetylacetonate TERT-BUTYL ISOCYANIDE METHYL ISOCYANOACETATE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) Benzyl isocyanide SALCOMINE TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III) PHENYLSELENOL COBALT(II) ACETYLACETONATE Ethyl isocyanoacetate Cupric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) Aluminum acetylacetonate 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE Tosylmethyl isocyanide DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) 2,4-PENTANEDIONE, SILVER DERIVATIVE CYTIDINE 5'-MONOPHOSPHO-N-

α2-3,6,8,9-Neuraminidase, Arthrobacter ureafaciens, Recombinant, E. coli

α2-3,6-Neuraminidase, Clostridium perfringens, Recombinant, E. coli

EC 3.2.1.18

EC 3.2.1.18 TYPE II

EC 3.2.1.18 TYPE III

EC 3.2.1.18 TYPE V

EC 3.2.1.18 TYPE VI

EC 3.2.1.18 TYPE VI-A

EC 3.2.1.18 TYPE VIII

EC 3.2.1.18 TYPE X

IUB: 3.2.1.18

ACYLNEURAMINYL HYDROLASE

ACYLNEURAMINYL HYDROLASE TYPE II

ACYLNEURAMINYL HYDROLASE TYPE III

ACYLNEURAMINYL HYDROLASE TYPE V

ACYLNEURAMINYL HYDROLASE TYPE VI

ACYLNEURAMINYL HYDROLASE TYPE VI-A

ACYLNEURAMINYL HYDROLASE TYPE VIII

ACYLNEURAMINYL HYDROLASE TYPE X

ACYLNEURAMYL HYDROLASE

ACETYLNEURAMINYL HYDROLASE

ACETYLNEURAMINYL HYDROLASE AGAROSE

ALPHA2,3-NEURAMINIDASE

ALPHA2,3-NEURAMINIDASE, MACROBDELLA DECORA

ALPHA2-3,6,8,9-NEURAMINIDASE

a2,3-Neuraminidase, Macrobdella decora, Recomb.

a2,3-Neuraminidase, Streptococcus pneumoniae

a2-3,6,8,9-Neuraminidase, Arthrobacter ureafaciens, Recomb.

a2-3,6,8,9-Neuraminidase, Recomb., E. coli

a2-3,6,8-Neuraminidase, Clostridium perfringens

a2-3,6,8-Neuraminidase, Vibriocholerae

Neuraminidase Clostridium perfringens (C.elchii)

neuraminidase from arthrobacter*ureafaciens

neuraminidase from clostridium perfrin-gens

neuraminidase from newcastle*disease virus

neuraminidase from vibrio cholerae

Neuraminidase solution from Vibrio cholerae

neuraminidase type vi from clostridium*perfringen

neuraminidase type X from*clostridium perfringens

NEURAMINIDASE FROM VIBRIO CHOLERAE, ~2 U /ML

NEURAMINIDASE TYPE II FROM VIBRIO*CHOLER AE

A-2(3,6,8,9)-NEURAMINIDASE, EXPRESSED*IN E. COLI

NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-&

A-2(3,6)-NEURAMINIDASE, RECOMBINANT*EXPR ESSED IN E.

NEURAMINIDASE FROM STREPTOCOCCUS SP.

NEURAMINIDASE TYPE VI FROM CLOSTRIDIUM*P ERFRINGENS

NEURAMINIDASE, WIDE SPECTRUM, PROTEOMICS

NEURAMINIDASE TYPE III FROM VIBRIO*CHOLE RAE

NEURAMINIDASE FROM SALMONELLA &

NEURAMINIDASE F. CLOSTRIDIUM PERFRINGENS , >4 U/VIAL, 25 UG*

A-2,3-NEURAMINIDASE, RECOMBINANT,*EXPRES SED IN E. C

A(2-->3 6 8 9) NEURAMINIDASE FROM &

NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-G ENS, ~1 U/MG

NEURAMINIDASE TYPE V FROM CLOSTRIDIUM*PE RFRINGENS

NEURAMINIDASE TYPE VIII FROM*CLOSTRIDIUM PERFRINGEN

NeuraminidaseExVibrioComa(Cholerae)

neuraminidase from clostridium perfringens (c. welchii)

α(2→3) neuraminidase from streptococcus pneumoniae