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Neuraminidase

Product Name
Neuraminidase
CAS No.
9001-67-6
Chemical Name
Neuraminidase
Synonyms
SIALIDASE;EC 3.2.1.18;SIALIDASE L;IUB: 3.2.1.18;ALP Separator;NEURAMINIDASE;Neuraminidase B;Neuraminidase A;exo-α-sialidase;3) Neuraminidase
CBNumber
CB9348886
Molecular Formula
NULL
Formula Weight
0
MOL File
Mol file
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Neuraminidase Property

Density 
1.00 g/mL at 20 °C
storage temp. 
2-8°C
form 
lyophilized powder
color 
white
Water Solubility 
Soluble in water or 10mM phosphate buffer, pH 6.0
EPA Substance Registry System
Neuraminidase (9001-67-6)
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Safety

Safety Statements 
22-24/25
RIDADR 
UN3373 - class 6.2 Biological substance, Category B
WGK Germany 
3
RTECS 
QQ3450000
3-10
TSCA 
Yes
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H290May be corrosive to metals

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P234Keep only in original container.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
N7885
Product name
Neuraminidase from Vibrio cholerae
Purity
Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
Packaging
1unit
Price
$181
Updated
2024/03/01
Sigma-Aldrich
Product number
N8271
Product name
α(2→3,6,8,9) Neuraminidase from Arthrobacter ureafaciens
Purity
recombinant, expressed in E. coli, buffered aqueous solution
Packaging
0.2unit
Price
$638
Updated
2024/03/01
Sigma-Aldrich
Product number
N7885
Product name
Neuraminidase from Vibrio cholerae
Purity
Type III, buffered aqueous solution, 0.2 μm filtered, 1-5?units/mg protein (Lowry, using NAN-lactose)
Packaging
2units
Price
$332
Updated
2024/03/01
Sigma-Aldrich
Product number
N5631
Product name
Neuraminidase from Clostridium perfringens (C. welchii)
Purity
Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
Packaging
1unit
Price
$69.2
Updated
2024/03/01
Sigma-Aldrich
Product number
N5631
Product name
Neuraminidase from Clostridium perfringens (C. welchii)
Purity
Type VIII, lyophilized powder, 10-20?units/mg protein (using 4MU-NANA), 3.5-8.0?units/mg protein (mucin)
Packaging
5units
Price
$226
Updated
2024/03/01
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Neuraminidase Chemical Properties,Usage,Production

Uses

Neuraminidase is used as a hydrolytic enzyme that removes sialic acid from mucoproteins, used in a study to assess binding with human T lymphocytes in sheep pretreated with neuraminidase. It has also been used in a study to investigate the effect of bile salts on the action of hydrolysis by neuraminidase.

Uses

Neuraminidase is an important deglycosylation enzyme capable of cleaving all non-reducing unbranched N-acetylneuraminic and N-glycolylneuraminic acid residues by hydrolysis of α(2→6), α(2→3), α(2→8), and α(2→9) linkages (affinity in the order given). Branched sialic acids may also be cleaved with the use of high concentrations of enzyme and prolonged incubations. Desialylated glycoproteins may then be further characterized by treatment with various exoglycosidases resulting in partial or complete O-deglycosylation. SDS-PAGE and MALDI-TOF MS are typically utilized in purification, structural analysis, and sequencing process. These techniques also remove heterogeneity and charge from the glycoprotein.

Uses

Neuraminidase from Vibrio cholera has been used in a study to describe a five-step purification method. It has also been used in a study to investigate modification of leukemia L1210 tumor cells.

General Description

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

Biochem/physiol Actions

Vibrio cholerae neuraminidase has been shown to promote cholera toxin infection by binding the toxin and aiding in its uptake by cells.

Neuraminidase Preparation Products And Raw materials

Raw materials

Preparation Products

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Neuraminidase Suppliers

Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
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View Lastest Price from Neuraminidase manufacturers

Hubei Xindesheng Material Technology Co., Ltd.
Product
neuraminidase 9001-67-6
Price
US $42.00-38.80/KU
Min. Order
10KU
Purity
≥400U/mg
Supply Ability
1000ku
Release date
2020-11-04
Career Henan Chemical Co
Product
ACETYLNEURAMINYL HYDROLASE 9001-67-6
Price
US $2.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100kg
Release date
2020-01-07

9001-67-6, NeuraminidaseRelated Search:


  • α2-3,6,8,9-Neuraminidase, Arthrobacter ureafaciens, Recombinant, E. coli
  • α2-3,6-Neuraminidase, Clostridium perfringens, Recombinant, E. coli
  • EC 3.2.1.18
  • EC 3.2.1.18 TYPE II
  • EC 3.2.1.18 TYPE III
  • EC 3.2.1.18 TYPE V
  • EC 3.2.1.18 TYPE VI
  • EC 3.2.1.18 TYPE VI-A
  • EC 3.2.1.18 TYPE VIII
  • EC 3.2.1.18 TYPE X
  • IUB: 3.2.1.18
  • ACYLNEURAMINYL HYDROLASE
  • ACYLNEURAMINYL HYDROLASE TYPE II
  • ACYLNEURAMINYL HYDROLASE TYPE III
  • ACYLNEURAMINYL HYDROLASE TYPE V
  • ACYLNEURAMINYL HYDROLASE TYPE VI
  • ACYLNEURAMINYL HYDROLASE TYPE VI-A
  • ACYLNEURAMINYL HYDROLASE TYPE VIII
  • ACYLNEURAMINYL HYDROLASE TYPE X
  • ACYLNEURAMYL HYDROLASE
  • ACETYLNEURAMINYL HYDROLASE
  • ACETYLNEURAMINYL HYDROLASE AGAROSE
  • ALPHA2,3-NEURAMINIDASE
  • ALPHA2,3-NEURAMINIDASE, MACROBDELLA DECORA
  • ALPHA2-3,6,8,9-NEURAMINIDASE
  • a2,3-Neuraminidase, Macrobdella decora, Recomb.
  • a2,3-Neuraminidase, Streptococcus pneumoniae
  • a2-3,6,8,9-Neuraminidase, Arthrobacter ureafaciens, Recomb.
  • a2-3,6,8,9-Neuraminidase, Recomb., E. coli
  • a2-3,6,8-Neuraminidase, Clostridium perfringens
  • a2-3,6,8-Neuraminidase, Vibriocholerae
  • Neuraminidase Clostridium perfringens (C.elchii)
  • neuraminidase from arthrobacter*ureafaciens
  • neuraminidase from clostridium perfrin-gens
  • neuraminidase from newcastle*disease virus
  • neuraminidase from vibrio cholerae
  • Neuraminidase solution from Vibrio cholerae
  • neuraminidase type vi from clostridium*perfringen
  • neuraminidase type X from*clostridium perfringens
  • NEURAMINIDASE FROM VIBRIO CHOLERAE, ~2 U /ML
  • NEURAMINIDASE TYPE II FROM VIBRIO*CHOLER AE
  • A-2(3,6,8,9)-NEURAMINIDASE, EXPRESSED*IN E. COLI
  • NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-&
  • A-2(3,6)-NEURAMINIDASE, RECOMBINANT*EXPR ESSED IN E.
  • NEURAMINIDASE FROM STREPTOCOCCUS SP.
  • NEURAMINIDASE TYPE VI FROM CLOSTRIDIUM*P ERFRINGENS
  • NEURAMINIDASE, WIDE SPECTRUM, PROTEOMICS
  • NEURAMINIDASE TYPE III FROM VIBRIO*CHOLE RAE
  • NEURAMINIDASE FROM SALMONELLA &
  • NEURAMINIDASE F. CLOSTRIDIUM PERFRINGENS , >4 U/VIAL, 25 UG*
  • A-2,3-NEURAMINIDASE, RECOMBINANT,*EXPRES SED IN E. C
  • A(2-->3 6 8 9) NEURAMINIDASE FROM &
  • NEURAMINIDASE FROM CLOSTRIDIUM PERFRIN-G ENS, ~1 U/MG
  • NEURAMINIDASE TYPE V FROM CLOSTRIDIUM*PE RFRINGENS
  • NEURAMINIDASE TYPE VIII FROM*CLOSTRIDIUM PERFRINGEN
  • NeuraminidaseExVibrioComa(Cholerae)
  • neuraminidase from clostridium perfringens (c. welchii)
  • α(2→3) neuraminidase from streptococcus pneumoniae