EC 2.7.1.40

ChemicalBook > CAS DataBase List > EC 2.7.1.40

Product Name: EC 2.7.1.40
CAS No.: 9001-59-6
Chemical Name: EC 2.7.1.40
Synonyms: PK;EC 2.7.1.40;pyruvic kinase;PYRUVATE KINASE;PK （rabbit muscle);Pyruvate Kinase M2;EC 2.7.1.40 USP/EP/BP;pyruvate phosphoferase;PYRUVATE KINASE TYPE I;PYRUVATE KINASE TYPE II
CBNumber: CB9396847
Molecular Formula: NULL
Formula Weight: 0
MOL File: Mol file

Less

EC 2.7.1.40 Property

storage temp.: -20°C
form: powder
color: white
Water Solubility: Soluble in water ( 1mg/ml).
EPA Substance Registry System: Kinase (phosphorylating), pyruvate (9001-59-6)

Less

Safety

WGK Germany: 3
F: 10-21
TSCA: Yes
HS Code: 35079090

Less

Hazard and Precautionary Statements (GHS)

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P9136
Product name: Pyruvate Kinase from rabbit muscle
Purity: Type III, lyophilized powder, 350-600?units/mg protein
Packaging: 1000units
Price: $79.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: P9136
Product name: Pyruvate Kinase from rabbit muscle
Purity: Type III, lyophilized powder, 350-600?units/mg protein
Packaging: 5000units
Price: $199
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRP0414
Product name: PKLR Var2 active human
Purity: recombinant,expressedinE.coli,≥90%(SDS-PAGE)
Packaging: 20μg
Price: $653
Updated: 2024/03/01

Sigma-Aldrich

Product number: SRP0413
Product name: PKLR Var1 active human
Purity: recombinant,expressedinE.coli,≥43%(SDS-PAGE)
Packaging: 20μg
Price: $653
Updated: 2024/03/01

Sigma-Aldrich

Product number: P9136
Product name: Pyruvate Kinase from rabbit muscle
Purity: Type III, lyophilized powder, 350-600?units/mg protein
Packaging: 25000units
Price: $602
Updated: 2024/03/01

Less

EC 2.7.1.40 Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Pyruvate kinase has been used in the preparation of cell free extract from BL21 CP strain of E. coli culture for highly productive cell-free protein expression. The enzyme has been used to assay the pyruvate kinase activity by incubating with eluted DAPk (Death-associated protein kinase), a serine/threonine kinase that binds and activates pyruvate kinase. It is involved in glycolysis and in gluconeogenesis. It has been used in PGM enzyme assays to determine phosphoglycerate mutase activity. It is also used to study pyruvate kinase (PK) deficiency.

Uses

Pyruvate kinase from rabbit muscle has been used in a structural study to understand the reaction mechanism of the final step in glycolysis. It has also been used in a study to investigate ATP-dependent phosphorylation of α-substituted carboxylic acids.

Uses

Pyruvate kinase from Bacillus stearothermophilus has been used in a study to assess evidence that the genes for phosphofructokinase and pyruvate kinase constitute an operon. It has also been used in a study to investigate the importance of the Lys221 active site for pyruvate kinase activity.

General Description

Pyruvate Kinase (PK) is a glycolysis enzyme and has four isozymes L, R, M₁, and M₂. The L isozyme is localized in gluconeogenic tissues, particularly in the liver. Whereas the R and M₁ are localized in the adult skeletal muscles, heart, brain and erythrocytes, respectively. M₂ is localized in the nucleus of the cells.

Biochem/physiol Actions

Molecular Weight: 237 kDa?and exists as a tetramer of four equal subunits of molecular weight 57 kDa.Isoelectric Point: 7.6Optimal pH: ～7.5 Optimal Temperature: 25°C ΕA280 = 0.54 for 1 mg(p)/ml, 1 cm path Reported KM values are ATP (0.86 mM), pyruvate (10 mM), ADP (0.3 mM), and PEP (0.07 mM) in Tris buffer at pH 7.4 and 30 °C. Pyruvate kinase is highly specific for phosphoenolpyruvate, but can utilize other dinucleotide triphosphates as substrates in place of ATP including GTP, ITP, dATP, UTP, and CTP.

Purification Methods

These are purified by (NH4)2SO4 fractionation and gel filtration, ion-exchange and affinity chromatography. [Garcia-Olalla & Garrido-Pertierra Biochem J 241 573 1987.]

EC 2.7.1.40 Preparation Products And Raw materials

Raw materials

Ammonium sulfate

Preparation Products

Less

EC 2.7.1.40 Suppliers

China 117 Europe 2 France 1 Germany 4 India 3 Japan 3 Switzerland 1 United Kingdom 2 United States 11 Global 144

Shanghai Baoman Biotechnology Co., Ltd.

Tel: 021-62130998
Fax: 021-54438215
Email: baomanbio@163.com
Country: China
ProdList: 105
Advantage: 55

Hubei HongxinRuiYu Fine Chemical Co., Ltd.

Tel: 027-027-65381247 15671591110
Fax: 027-65526669
Email: 3074722151@qq.com
Country: China
ProdList: 137
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94837
Advantage: 76

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4941
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9725
Advantage: 55

Nanjing Dulai Biotechnology Co., Ltd.

Tel: 025-84699383-8003 18013301590
Fax: 025-84699383-8003
Email: njduly@126.com
Country: China
ProdList: 973
Advantage: 55

Nanjing Sunlida Biological Technology Co., Ltd.

Tel: 025-57798810
Fax: 025-57019371
Email: sales@sunlidabio.com
Country: China
ProdList: 3750
Advantage: 55

Shanghai BeiZhuo Biotech Co., Ltd.

Tel: 021-61119791,13386096464
Fax: 021-50190009
Email: bzswkf@foxmail.com
Country: China
ProdList: 3924
Advantage: 50

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13359
Advantage: 58

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 15885
Advantage: 55

Chengdu RunZeBenTu Chemical Co., Ltd

Tel: 13096311329 028-88469284 616445927
Fax: 028-88469284
Email: 616445927@qq.com
Country: China
ProdList: 2876
Advantage: 50

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9955
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Watson Biotechnology Co.,Ltd

Tel: 027-027-59207879 18140587686
Fax: QQ：1972026995
Email: kf@3600chem.com
Country: China
ProdList: 4697
Advantage: 55

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20810
Advantage: 60

Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4534
Advantage: 58

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9951
Advantage: 58

Beijing Solarbio Science & Tecnology Co., Ltd.

Tel: 010-50973130 4009686088
Email: 3193328036@qq.com
Country: China
ProdList: 29795
Advantage: 68

Shanghai Yihe Biological Technology Co., Ltd.

Tel: 17721395025
Fax: 021-68882955
Email: 2423903095@qq.com
Country: China
ProdList: 3180
Advantage: 58

Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

Tel: 027-65526929 15102793023
Fax: 027-65526669
Email: hbhxry@foxmail.com
Country: China
ProdList: 2059
Advantage: 55

Guangzhou LES biological Technology Co.,Ltd.

Tel: 13672434928
Fax: -
Email: 3307355104@qq.com
Country: China
ProdList: 3650
Advantage: 58

Shenzhen Regent Biochemical Technology Co., Ltd.

Tel: 0755-0755-85201366 18938635012
Fax: 0755-85201366
Email: sales@regentsciences.com
Country: China
ProdList: 9303
Advantage: 58

Aikon International Limited

Tel: 025-58851090 13611564524
Fax: (6)02557626880
Email: lwan@aikonchem.com
Country: China
ProdList: 15952
Advantage: 58

Hubei widely chemical technology Co., Ltd.

Tel: 027-83778895 18602735115
Fax: 027-51119224
Email: 18602735115@163.com
Country: China
ProdList: 1997
Advantage: 64

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920564737
Email: sales@heowns.com
Country: China
ProdList: 20632
Advantage: 60

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 6912
Advantage: 58

Hefei Bomei Biotechnology Co., Ltd.

Tel: 13739298932
Email: 531626407@qq.com
Country: China
ProdList: 3008
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 56056
Advantage: 58

Hubei Hongxin Ruiyu Fine Chemical Co., Ltd.

Tel: 027-65526669 17771822910
Fax: 027-65526669
Email: 2056564811@qq.com
Country: China
ProdList: 1822
Advantage: 58

Guangzhou Tomums Life Science Co., Ltd.

Tel: 020-31155029 18902330969
Fax: 020-31155029
Email: sales@tomums.cn
Country: China
ProdList: 4698
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23556
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: 0551-65418671
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34571
Advantage: 58

Wuhan Fortuna Chemical Co., Ltd

Tel: +86-027-59207850
Fax: 86-27-59524646
Email: info@fortunachem.com
Country: China
ProdList: 5999
Advantage: 58

Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 27027
Advantage: 58

HANGZHOU CLAP TECHNOLOGY CO.,LTD

Tel: 86-571-88216897,88216896 13588875226
Fax: 86-571-88216895
Email: sales@hzclap.com
Country: CHINA
ProdList: 6313
Advantage: 58

HUNAN CHEMFISH SCIENTIFIC CO.,LTD

Tel: 13021512891
Fax: QQ:3554193828
Email: sales04@chemfish.com
Country: China
ProdList: 6651
Advantage: 58

Xibao Biotechnology (Shanghai) Co., Ltd.

Tel: 13761246140
Email: 58642714@qq.com
Country: China
ProdList: 415
Advantage: 58

Shanghai Jiange Chemical Co., Ltd.

Tel: 15921040873
Email: 1434142450@qq.com
Country: CHINA
ProdList: 7651
Advantage: 58

Shanghai Hongshun Biological Technology Co., Ltd.

Tel: 15901914505
Fax: 021-54389085
Email: 3187892335@qq.com
Country: China
ProdList: 9102
Advantage: 58

Hubei New Desheng Materials Technology Co., Ltd.

Tel: 18971041571
Fax: 0711-3704589
Email: vickyzhao@whdschem.com
Country: China
ProdList: 57
Advantage: 58

Shanghai Yanze Chemical Co., Ltd.

Tel: 021-13773155751 19901447308
Email: 260924549@qq.com
Country: China
ProdList: 8756
Advantage: 58

Chongqing Chemdad Co., Ltd

Tel: +86-023-6139-8061 +86-86-13650506873
Email: sales@chemdad.com
Country: China
ProdList: 39916
Advantage: 58

Shanghai jingkang bioengineering co., ltd.

Tel: 021-54721350 13524668266
Fax: 021-5
Email: 2881505714@qq.com
Country: China
ProdList: 7878
Advantage: 58

Shanghai Kanglang Biotechnology Co., Ltd.

Tel: 021-61998208 18217752821
Fax: 021-37680378
Email: sales@klbio.cn
Country: China
ProdList: 9617
Advantage: 58

CONIER CHEM AND PHARMA LIMITED

Tel: +8618523575427
Email: sales@conier.com
Country: China
ProdList: 49391
Advantage: 58

Wuhan lanabai Pharmaceutical Chemical Co., Ltd

Tel: 15307151931
Fax: QQ-2355680
Email: 2355680@qq.com
Country: China
ProdList: 8175
Advantage: 58

Shanghai Sig Biotechnology Co., LTD

Tel: 021-57810052 18930344717
Fax: 021-57810052
Email: 2089316240@qq.com
Country: China
ProdList: 9396
Advantage: 58

Ontores Biotech

Tel: 0571-88760729 18072970094
Email: supports@ontorespeptide.com
Country: China
ProdList: 2696
Advantage: 58

Henan Weitesi Chemical Technology Co. LTD

Tel: 0371-0371-55135753 18003832934
Fax: QQ：2853979818
Email: 2853979818@qq.com
Country: China
ProdList: 9992
Advantage: 58

Less

View Lastest Price from EC 2.7.1.40 manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Pyruvate Kinase 9001-59-6
Price: US $0.00-0.00/g
Min. Order: 1g
Purity: 98.0%
Supply Ability: 1kg/month
Release date: 2021-08-24

Hubei Xindesheng Material Technology Co., Ltd.

Product: Pyruvate Kinase 9001-59-6
Price: US $12.00-9.00/KU
Min. Order: 10KU
Purity: ≥ 25.0U/mg
Supply Ability: 10000ku
Release date: 2020-11-04

Career Henan Chemical Co

Product: carnosine 9001-59-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 95%-99%
Supply Ability: 1000kg
Release date: 2018-12-25

9001-59-6, EC 2.7.1.40Related Search:

Ethyl isocyanoacetate Ferric acetylacetonate Cupric acetylacetonate Tris(2,4-pentanedionato)chroMiuM(III) TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)DYSPROSIUM(III) 1,1,3,3-TETRAMETHYLBUTYL ISOCYANIDE COBALT(II) ACETYLACETONATE Tosylmethyl isocyanide Benzyl isocyanide Aluminum acetylacetonate DICHLORO(ETHYLENEDIAMINE)PLATINUM(II) TERT-BUTYL ISOCYANIDE N-BUTYLISOCYANIDE METHYL ISOCYANOACETATE SALCOMINE 2,4-PENTANEDIONE, SILVER DERIVATIVE PHENYLSELENOL TRIS(2,2,6,6-TETRAMETHYL-3,5-HEPTANEDIONATO)EUROPIUM(III)

ATP:PYRUVATE 2-O-PHOSPHOTRANSFERASE

ATP: PYRUVATE O2-PHOSPHOTRANSFERASE

EC 2.7.1.40

PK （rabbit muscle)

pyruvate phosphoferase

PYRUVATE KINASE FROM RABBITMUSCLE CA. 350 U/MG PROTEIN SUSP.

Pyruvate Kinase from Bacillus stearothermophilus,ATP:pyruvate 2-O-phosphotransferase, PK

Pyruvate Kinase from rabbit muscle,ATP:pyruvate 2-O-phosphotransferase, PK

PYRUVATE KINASE, PRESTAINED FROM*CHICKEN MUSCLE

PK(R.M.), ATP: pyruvate 2-o-phosphotransferase

Pyruvate kinase (from Rabbit muscle), ammonium sulfate suspension

Pyruvat kinase from rabbit, lyophil.

PHOSPHOENOL PYRUVATE KINASE

PYRUVATE KINASE

PYRUVATE KINASE, RABBIT MUSCLE

PYRUVATE KINASE TYPE I

PYRUVATE KINASE TYPE II

PYRUVATE KINASE TYPE III

PYRUVATE KINASE TYPE VIII

PYRUVATE O2-PHOSPHO TRANSFERASE

Pyruvate Kinase, 250 units/Mg

Pyruvate Kinase froM MicroorganisM

Pyruvate Kinase from rabbit liver

Pyruvate Kinase M2

pyruvate kinase from rabbit muscle

pyruvate kinase from rabbit muscle cryst susp. ~350 U/mg

Pyruvate Kinase preparation from rabbit muscle

pyruvate kinase type I crude*from rabbit muscle

pyruvate kinase type iii from rabbit*muscle

pyruvate kinase type viii from*bacillus stearothe

pyruvate kinase type X from chicken*muscle

pyruvate kinase type xii from rabbit*liver

Kinase (phosphorylating), pyruvate

PYRUVATE KINASE TYPE X FROM CHICKEN &

PYRUVATE KINASE TYPE VII FROM*RABBIT MUS CLE

PYRUVATE KINASE PRESTAINED FROM CHICKEN

PYRUVATE KINASE FROM RABBIT MUSCLE, 100- 250 U/MG

PYRUVATE KINASE TYPE VIII FROM*BACILLUS STEAROTHERM

PYRUVATE KINASE TYPE II FROM RABBIT*MUSC LE

PYRUVATE KINASE (EC 2.7.1.40) FROM RABBIT MUSCLE LYOPHILIZED POWDER ESSENTIALLY SALT-FREE

PYRUVATE KINASE FROM PORCINE HEART (E.C. 2.7.1.40)

PYRUVATE KINASE (EC 2.7.1.40) FROM RABBIT MUSCLE HIGHLY PURIFIED SUSPENSION

PYRUVATE KINASE FROM BACILLUS STEAROTHERMOPHILUS

PyruvateKinaseExRabbitMuscle

Pyruvate kinase from rabbit muscle ca. 350 U/mg protein

pyruvic kinase

ATP:pyruvate 2-O-phosphotransferase, PK

Pyruvate Kinase preparation from canine muscle

phosphopyruvate transphos phorylase

Pyruvate Kinase, 50 units/mg

Pyruvate Kinase M2 from Human, Recombinant

Pyruvate kinase M2 Active from Mouse, Recombinant

Native Pyruvate Kinase from Thermophillic bacteria

Native Bacillus stearothermophilus Pyruvate Kinase

EC 2.7.1.40 USP/EP/BP

Pyruvate Kinase ex. Rabbit Muscle, 300U/mg

9001-59-6