ALPHA1-ANTICHYMOTRYPSIN, HUMAN

Product Name: ALPHA1-ANTICHYMOTRYPSIN, HUMAN
CAS No.: 141176-92-3
Chemical Name: ALPHA1-ANTICHYMOTRYPSIN, HUMAN
Synonyms: ACT;GIG24;GIG25;ALPHA-1-X;AACT, HUMAN;ANTI-AACT, HUMAN;ALPHA1-1X, HUMAN;ALPHA1-ACHY, HUMAN;α-Antichymotrypsin;ALPHA-1-X-GLYCOPROTEIN
CBNumber: CB9738283
Formula Weight: 0
MOL File: Mol file

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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Property

storage temp.: -20°C
solubility: aqueous buffer: soluble
form: lyophilized powder
biological source: human plasma
Specific Activity: ≥85%, pH 7.4, 25°C (using Suc-Ala-Ala-Pro-Phe-pNA as substrate, inhibition of cathepsin G)

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Safety

Hazard Codes: B
WGK Germany: 3
HS Code: 3504009000
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P3360
Product name: Prostate Specific Antigen–α1-Antichymotrypsin Complex human
Purity: ≥99%(SDS-PAGE),bufferedaqueoussolution
Packaging: 10μg
Price: $818
Updated: 2026/03/19

Sigma-Aldrich

Product number: 178196
Product name: α₁-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem
Purity: Acute-phase protein present at ~45 mg/100 ml in plasma.
Packaging: 100μg
Price: $175
Updated: 2026/03/19

Sigma-Aldrich

Product number: A9285
Product name: α1-Antichymotrypsin from human plasma
Purity: ≥92.5% (SDS-PAGE), lyophilized powder
Packaging: 0.1mg
Price: $234
Updated: 2026/03/19

Sigma-Aldrich

Product number: 178196
Product name: α?-Antichymotrypsin, Human Plasma
Purity: Acute-phase protein present at ~45 mg/100 ml in plasma.
Packaging: 1mg
Price: $969
Updated: 2026/03/19

Apolloscientific

Product number: BITP1442
Product name: Human Alpha-1 AntiChymotrypsin
Packaging: 20μg
Price: $75
Updated: 2021/12/16

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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Chemical Properties,Usage,Production

Uses

α1-Antichymotrypsin from human plasma has been used as a component in yeast extract peptone dextrose broth (YEPD) for biofilm dispersion assays.

General Description

Kallikrein-3 (KLK3) or prostate specific antigen (PSA) is a serine protease. The protein contains a 371-residue N-terminal heavy chain, which is composed of four Apple domains. The PSA gene is localized to human chromosome 4q35. PSA is synthesized in the liver as a proenzyme known as prekallikrein. It is a key component of the kinin-generating pathways (PK system). The protein is involved in important physiological roles, such as blood pressure modulation, complement activation, and control and maintenance of inflammatory responses. KLK3b alleles are found to be associated with end-stage renal disease (ESRD) suggesting that variants in KLK3 gene might be linked with ESRD susceptibility.
SERPINA3 is also known as α-1-antichymotrypsin (ACT or AACT). The gene consists of five exons and is mapped to human chromosome 14q32.13. The protein contains 423 amino acids and belongs to the family of serpin superfamily of protease inhibitors. SERPINA3 inhibits the activity of pancreatic chymotrypsin, leukocyte, cathepsin G, mast cell chymases, human glandular, kallikrein 2 and kallikrein 3. Elevated expression of the protein has been observed in various types of carcinomas including breast carcinoma, hepatocellular carcinoma, prostate carcinoma and adenocarcinoma of the lung.

Biochem/physiol Actions

α1-Antichymotrypsin (α1-ACT) can block the functions of various serine proteases like chymotrypsin and cathepsin G. It serves as a potential therapeutic target of endometrial carcinoma (EC).

ALPHA1-ANTICHYMOTRYPSIN, HUMAN Preparation Products And Raw materials

Raw materials

Preparation Products

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ALPHA1-ANTICHYMOTRYPSIN, HUMAN Suppliers

China 31 Europe 2 Germany 3 Japan 1 Switzerland 1 United Kingdom 2 United States 9 Global 49

Nanjing Dulai Biotechnology Co., Ltd.

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Sigma-Aldrich

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Merck KGaA

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Signalway Antibody LLC

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141176-92-3, ALPHA1-ANTICHYMOTRYPSIN, HUMANRelated Search:

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A1-ANTICHYMOTRYPSIN FROM HUMAN PLASMA

Antichymotrypsin from human plasma

α1-antichymotrypsin from human plasma

Human Alpha-1 AntiChymotrypsin

ANTI-ANTICHYMOTRYPSIN, ALPHA-1-, HUMAN

ANTI-AACT, HUMAN

ANTICHYMOTRYPSIN, ALPHA-1, HUMAN

AACT, HUMAN

ACT

ALPHA-1-X

ALPHA-1-X-GLYCOPROTEIN

ALPHA-1X-GLYCOPROTEIN, HUMAN

ALPHA1-ANTICHYMOTRYPSIN

ALPHA1-ANTICHYMOTRYPSIN, HUMAN

ALPHA1-ANTICHYMOTRYPSIN, HUMAN PLASMA

ALPHA-1 ANTICHYMOTRYPSIN PLASMA

ALPHA1-ACHY, HUMAN

ALPHA1-1X-GLYCOPROTEIN, HUMAN

ALPHA1-1X, HUMAN

α?-Antichymotrypsin, Human Plasma

α-Antichymotrypsin, Human Plasma - CAS 141176-92-3 - Calbiochem

α-Antichymotrypsin

α1-Antichymotrypsin, from human plasma

α<sub>1</sub>-Antichymotrypsin, Human Plasma

α<sub>1</sub>-Antichymotrypsin from human plasma

Prostate Specific Antigen–α1-Antichymotrypsin Complex human

GIG24

GIG25

141176-92-3

Biochemicals and Reagents

BioChemical

Cathepsin G

A to C

Enzymes, Inhibitors, and Substrates

Enzyme Inhibitors by Enzyme

Enzyme Inhibitors

proteins