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HigenaMine Hydrochloride

Basic information Toxicity Safety Supplier Related

HigenaMine Hydrochloride Basic information

Product Name:
HigenaMine Hydrochloride
Synonyms:
  • Demethyl
  • 1,2,3,4-Tetrahydro-1-((4-hydroxyphenyl)methyl)-6,7-isoquinolinediol hydrochloride
  • Higenamine hydrochloride
  • Dacacine base acid and alkali salt
  • 6,7-dihydroxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline
  • 6,7-Dihydroxy-1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
  • 6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (1:1)
  • 1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline-6,7-diol hydrochloride
CAS:
11041-94-4
MF:
C16H18ClNO3
MW:
307.77
EINECS:
1592732-453-0
Product Categories:
  • 11041-94-4
Mol File:
11041-94-4.mol
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HigenaMine Hydrochloride Chemical Properties

storage temp. 
4°C, protect from light
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Beige to Pale Brown
Stability:
Hygroscopic
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Safety Information

Toxicity
mouse,LD50,intravenous,17250ug/kg (17.25mg/kg),Zhongcaoyao. Chinese Traditional and Herbal Medicine. Vol. 13, Pg. 489, 1982.
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HigenaMine Hydrochloride Usage And Synthesis

Toxicity

The safety of orally administered higenamine hydrochloride in humans is unknown. During a study of acute toxicity, mice were orally administered the compound at a dose of 2 g per kg of bodyweight. No mice died during the study.In human trials of intravenous higenamine, subjects who received higenamine reported shortness of breath, racing heart, dizziness, headaches, chest tightness.

Description

Higenamine is a chemical found in several plants including aconite, Annona squamosa, Nandina domestica (sacred bamboo), and others. HigenaMine Hydrochloride is the hydrochloride form of higenamine.

Uses

Higenamine HCl (norcoclaurine) is a plant-based alkaloid widely used as nutritional supplement in food and beverage industries.

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