MPEG-SH Chemical Properties

storage temp. 

2-8°C, stored under nitrogen

form 

Solid

color 

White to off-white

InChI

InChI=1S/C25H52O12S/c1-26-2-3-27-4-5-28-6-7-29-8-9-30-10-11-31-12-13-32-14-15-33-16-17-34-18-19-35-20-21-36-22-23-37-24-25-38/h38H,2-25H2,1H3

InChIKey

MXDXXEVQFMVAIA-UHFFFAOYSA-N

SMILES

C(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCS)OC

Safety Information

WGK Germany 

3

MPEG-SH Usage And Synthesis

Description

m-PEG12-thiol is a PEG linker containing a thiol group. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

m-PEG-thiol (MW 1000) modifies DNA thiolation for the synthesis of gold nanorods (AuNRs). Thiolated DNA can be loaded onto AuNR by the mPEG-SH/Tween 20 assisted method (Tween 20 and mPEG-SH repeatedly displace CTAB on the AuNR surface). DNA AuNRs have been widely used in nanostructure assembly, gene therapy, biosensing, and drug delivery.

References

[1] Li J, et al. Simple and Rapid Functionalization of Gold Nanorods with Oligonucleotides Using an mPEG-SH/Tween 20-Assisted Approach. Langmuir. 2015 Jul 21;31(28):7869-76. DOI:10.1021/acs.langmuir.5b01680

MPEG-SH(134874-49-0)Related Product Information

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• DICHLORO(ETHYLENEDIAMINE)PLATINUM(II)
• Tris(2,4-pentanedionato)chroMiuM(III)
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