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4,4'-DIMETHOXYBENZHYDROL

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4,4'-DIMETHOXYBENZHYDROL Basic information

Product Name:
4,4'-DIMETHOXYBENZHYDROL
Synonyms:
  • Bis(4-methoxyphenyl) carbinol~4,4-Dimethoxydiphenylmethanol
  • p,p'-dimethoxybenzhydryl alcohol
  • 4,4'-Dimethoxybenzhydrol, 98+%
  • (4,4'-Dimethoxybenzhydryl) alcohol
  • (4-Methoxyphenyl)(4-methoxyphenyl)methanol
  • 4-Methoxy-α-(4-methoxyphenyl)benzenemethanol
  • α-(4-Methoxyphenyl)-4-methoxybenzenemethanol
  • BIS(4-METHOXYPHENYL)CARBINOL
CAS:
728-87-0
MF:
C15H16O3
MW:
244.29
EINECS:
211-975-9
Product Categories:
  • Benzhydrols, Benzyl & Special Alcohols
Mol File:
728-87-0.mol
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4,4'-DIMETHOXYBENZHYDROL Chemical Properties

Melting point:
67-70 °C(lit.)
Boiling point:
347.2°C (rough estimate)
Density 
1.1263 (rough estimate)
refractive index 
1.5570 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
methanol: 0.1 g/mL, clear
pka
13.68±0.20(Predicted)
form 
Solid
color 
White
Water Solubility 
Soluble in water (0.44 g/L @ 25°C), methanol (0.1 g/mL).
BRN 
748532
CAS DataBase Reference
728-87-0(CAS DataBase Reference)
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Safety Information

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
22-24/25-36/37-26
WGK Germany 
3
HS Code 
29094990

MSDS

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4,4'-DIMETHOXYBENZHYDROL Usage And Synthesis

Chemical Properties

white to off-white crystalline powder

Uses

4,4?-Dimethoxybenzhydrol was used to study the kinetics and mechanism of oxidation of substituted benzhydrols to corresponding benzophenones in the presence of Hg(OAc)2 by N-bromosuccinimide. It is useful in the protection of glutamine and asparagine residues in peptide synthesis, reagent for the N-protection of amides.

General Description

4,4′-Dimethoxybenzhydrol causes N-alkylation of amides, lactams, carbamates, ureas and anilines in acetic acid during H2SO4 catalysis.

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