2-Bromo-2-methylpropionic acid Chemical Properties

Melting point:

44-47 °C(lit.)

Boiling point:

198-200 °C(lit.)

Density 

1.43 g/cm3

refractive index 

1.4570 (estimate)

Flash point:

>230 °F

storage temp. 

under inert gas (nitrogen or Argon) at 2–8 °C

solubility 

soluble in Chloroform, Methanol

pka

2.91±0.10(Predicted)

form 

Liquid

color 

Clear colorless to slightly yellow

Water Solubility 

Soluble in alcohol and ether. Slightly soluble in water.

Merck 

14,1421

BRN 

1745543

Stability:

Stable. Incompatible with strong oxidizing agents, strong bases.

CAS DataBase Reference

2052-01-9(CAS DataBase Reference)

NIST Chemistry Reference

«alpha»-Bromoisobutyric acid(2052-01-9)

EPA Substance Registry System

Propanoic acid, 2-bromo-2-methyl- (2052-01-9)

Safety Information

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45-25

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

F 

13

TSCA 

Yes

HazardClass 

8

PackingGroup 

III

HS Code 

29156000

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

2-Bromo-2-methylpropionic acid Usage And Synthesis

Chemical Properties

white powder

Uses

2-Bromoisobutyric acid is used in the synthesis of dextran macroinitiator for atom transfer radical polymerization (ATRP) by partial esterification of hydroxyl group of the polysaccharide. The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

Uses

2-Bromo-2-methylpropionic acid is used in the Herceptin functionalization of polyhedral oligomeric silsesquioxane-conjugated oligomers-silica /iron oxide nanoparticles for tumor cell sorting.

General Description

The multifunctional silica colloids were prepared by coating them with 2-bromo-2-methylpropionic acid stabilized quantum dots.

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