5-Amino-2-chloropyridine Chemical Properties

Melting point:

81-83 °C(lit.)

Boiling point:

205.39°C (rough estimate)

Density 

1.2417 (rough estimate)

refractive index 

1.5110 (estimate)

storage temp. 

Keep in dark place,Inert atmosphere,Room temperature

form 

powder to crystal

pka

1.94±0.10(Predicted)

color 

White to Brown

BRN 

108891

InChIKey

QAJYCQZQLVENRZ-UHFFFAOYSA-N

CAS DataBase Reference

5350-93-6(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

29333999

MSDS

• Language:English Provider:5-Amino-2-chloropyridine
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

5-Amino-2-chloropyridine Usage And Synthesis

Chemical Properties

Light yellow to brown crystalline powder

Uses

5-Amino-2-chloropyridine was used in the synthesis of [²H₅]2-amino-l-methyl-6-phenylimidazo[4,5-b]pyridine. It was used in identification and evaluation of molecularly imprinted polymers for the selective removal of potentially genotoxic aminopyridine impurities from pharmaceuticals.

Definition

ChEBI: 3-Amino-6-chloropyridine is an aminopyridine.

General Description

5-Amino-2-chloropyridine undergoes Suzuki-Miyaura coupling with sterically hindered 2,6-dimethylphenylboronic acid. It undergoes facile temperature dependent displacement of chloride by bromide via Sandmeyer reaction to yield 2,5-dibromopyridine.

5-Amino-2-chloropyridine(5350-93-6)Related Product Information

• ALTRENOGEST
• Clopidol
• Tris(hydroxymethyl)aminomethane
• 3-Aminophenol
• 2-Chloro-5-chloromethylpyridine
• Glycine
• 3-Aminopyridine
• 6-Aminocaproic acid
• 4-Dimethylaminopyridine
• 2-Chloro-5-nitropyridine
• 2-Chloro-3-cyanopyridine
• 2-Aminopyridine
• 2-Chloropyridine
• 2-chloro-5-cyanopyridine
• 2-Chloro-5-fluoropyridine
• 3-Bromo-6-chloro-2-methylpyridine
• 5-Bromo-2-chloropyridine
• 6-Chloro-2-methyl-3-nitropyridine