6-Chloro-2-methyl-3-nitropyridine Chemical Properties

Melting point:

54-58 °C

Boiling point:

200°C (rough estimate)

Density 

1.5610 (rough estimate)

refractive index 

1.5500 (estimate)

storage temp. 

Keep in dark place,Sealed in dry,Room Temperature

pka

-3.26±0.10(Predicted)

form 

Powder

color 

Light beige to brown

InChI

InChI=1S/C6H5ClN2O2/c1-4-5(9(10)11)2-3-6(7)8-4/h2-3H,1H3

InChIKey

GHSRMSJVYMITDX-UHFFFAOYSA-N

SMILES

C1(C)=NC(Cl)=CC=C1[N+]([O-])=O

CAS DataBase Reference

22280-60-0(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xn,Xi

Risk Statements 

36/37/38-20/21/22-22

Safety Statements 

36/37/39-26

Hazard Note 

Harmful

HazardClass 

IRRITANT

HS Code 

29333990

MSDS

• Language:English Provider:ACROS

6-Chloro-2-methyl-3-nitropyridine Usage And Synthesis

Chemical Properties

Light yellow Cryst

Uses

6-Chloro-2-methyl-3-nitropyridine has been used as a reactant for the synthesis of fluorine-containing pyridinealdoxime derivatives as treatment of organophosphorus nerve-agent poisoning.

Preparation

A mixture of 2-oxo-5-nitro-6-methyl-1,2-dihydropyridine, phosphorous oxychloride, and phosphorous pentachloride was heated at 110° C for 2 hours, whereupon the reaction mixture was charged with an additional portion of phosphorous pentachloride and phosphorous oxychloride. The reaction was stirred for 1 hour and then poured into ice water. The brown solid was filtered and washed with cold water, to give 6-Chloro-2-methyl-3-nitropyridine (94%).

6-Chloro-2-methyl-3-nitropyridine(22280-60-0)Related Product Information

• Methyl acrylate
• 2-Chloro-5-methylpyridine
• Bensulfuron methyl
• Azamethiphos
• Kresoxim-methyl
• Methyl acetate
• 2,4,6-Collidine
• 3-Nitropyridine
• Thiophanate-methyl
• 6-Chloro-2-picoline
• 4-Methylpyridine
• 2-Chloro-5-chloromethylpyridine
• 2,6-Lutidine
• 2-Bromo-5-nitropyridine
• 2-Chloro-5-nitropyridine
• 2-Methyl-3-nitropyridine
• Methylparaben
• Methyl