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SAUCHINONE

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SAUCHINONE Basic information

Product Name:
SAUCHINONE
Synonyms:
  • (5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
  • (5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one
  • Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill
  • SAUCHINONE
  • (5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one
  • 5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-
  • Sauchinone >=98% (HPLC)
  • AI3 00896
CAS:
177931-17-8
MF:
C20H20O6
MW:
356.37
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
177931-17-8.mol
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SAUCHINONE Chemical Properties

Melting point:
224-226℃
Boiling point:
498.1±45.0 °C(Predicted)
Density 
1.43±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. 
2-8°C
solubility 
DMSO: soluble5mg/mL, clear (warmed)
form 
powder
color 
white to beige
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Safety Information

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29329990
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SAUCHINONE Usage And Synthesis

Uses

Sauchinone is a lignan first isolated from the aerial parts of S. chinensis, a plant used in Asian medicine for its anti-inflammatory, anti-angiogenic, and anti-nociceptive activities. Sauchinone has numerous effects on isolated cells, including blocking NF-κB activation in LPS-stimulated macrophages, inducing heme oxygenase-1 transcription in endothelial cells, and attenuating oxidative-stress-induced damage in myoblasts. Sauchinone is extensively metabolized in vivo, but intraperitoneal administration significantly reduces myocardial infarct size induced by ischemia/reperfusion in mice.

SAUCHINONESupplier

Sichuan Kulinan Technology Co., Ltd
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400-1166-196 18981987031
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cdhxsj@163.com
Dalian Meilun Biotech Co., Ltd.
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0411-62910999 13889544652
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meilunui@163.com
ShangHai YuanYe Biotechnology Co., Ltd.
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021-61312847 13636370518
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shyysw007@163.com
Chengdu Ai Keda Chemical Technology Co., Ltd.
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4008-755-333 18080918076
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800078821@qq.com
Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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cwb1@biopurify.cn