propanedial Chemical Properties

Melting point:

72-74°

Boiling point:

66.43°C (rough estimate)

Density 

0.9843 (rough estimate)

refractive index 

1.3670 (estimate)

solubility 

sol EtOH, MeOH, H2O; moderately sol CH2Cl2; insol ether.

pka

5(at 25℃)

InChI

InChI=1S/C3H4O2/c4-2-1-3-5/h2-3H,1H2

InChIKey

WSMYVTOQOOLQHP-UHFFFAOYSA-N

SMILES

C(=O)CC=O

LogP

-0.390 (est)

CAS DataBase Reference

542-78-9

IARC

3 (Vol. 36, Sup 7, 71) 1999

Safety Information

Hazardous Substances Data

542-78-9(Hazardous Substances Data)

Toxicity

LD50 orally in rats: 632 mg/kg (Crawford)

propanedial Usage And Synthesis

Uses

Propanedial, exists in horseradish hairy root taht has shown strong antioxidant capacity under arsenic stress which indicates possible use of Armoracia rusticana plants for phytoremediation.

Definition

Malonaldehyde is a dialdehyde that is propane substituted by two oxo groups at the terminal carbon atoms respectively. A biomarker of oxidative damage to lipids caused by smoking, it exists in vivo mainly in the enol form. It has a role as a biomarker.

storage

Unstable and easily polymerizes. The generation of MDA in situ from  the hydrolysis of its bis-acetals results in the formation of a number of side products, including β- alkoxyacrolein, 3,3-dialkoxypropionaldehyde, and fluorescent condensation polymers of MDA. Crystalline  sodium MDA, which is much more stable than MDA, is the recommended synthetic reagent. Sodium MDA,  if stored under nitrogen in a refrigerator, is stable for months.

propanedial(542-78-9)Related Product Information

• 1,3-Cyclopentanedione
• Diethyl 1,1-cyclopropanedicarboxylate
• METHYL 4-FLUOROBENZOYLACETATE
• 4'-Chloroacetoacetanilide
• Ethyl 4-chloroacetoacetate
• 3-(2-FLUORO-PHENYL)-3-OXO-PROPIONIC ACID ETHYL ESTER
• 4,4,4-Trifluoro-1-phenyl-1,3-butanedione
• Ethyl 4,4,4-trifluoroacetoacetate
• 2,2-DIMETHYL-6,6,7,7,8,8,8-HEPTAFLUORO-3,5-OCTANEDIONE
• Ethyl 2-oxocyclopentanecarboxylate
• HEXAFLUOROACETYLACETONE
• 4-CYCLOPENTENE-1,3-DIONE
• TETRAMETHYL-1,3-CYCLOBUTANEDIONE
• 1,1,1-Trifluoro-2,4-pentanedione
• Methyl 2-cyclopentanonecarboxylate
• Malonyl chloride
• 1,1-Cyclobutanedicarboxylic acid
• Methyl 4-chloro-3-oxo-butanoate