ChemicalBook > Product Catalog > Chemical Reagents > Organic reagents > Esters > Ethyl compound > Ethyl 4,4,4-trifluoroacetoacetate
Ethyl 4,4,4-trifluoroacetoacetate
Ethyl 4,4,4-trifluoroacetoacetate Basic information
- Product Name:
- Ethyl 4,4,4-trifluoroacetoacetate
- Synonyms:
-
- Ethyl4,4,-Trifluoroacetoacetate
- Ethyltrifluoroacetoacetate,98+%
- ETHYL 4,4,4-TRIFLUOROACETYLACETATE
- ETFAA
- 1-Ethoxy-4,4,4-trifluorobutane-1,3-dione
- Ethyl 3-oxo-4,4,4-trifluorobutanoate
- Ethyl 4,4,4-trifluoro-3-oxobutyrate
- (Trifluoroacetyl)acetic acid ethyl ester
- CAS:
- 372-31-6
- MF:
- C6H7F3O3
- MW:
- 184.11
- EINECS:
- 206-750-7
- Product Categories:
-
- Fluorinated Building Blocks
- Fluorinating Reagents & Building Blocks for Fluorinated Biochemical Compounds
- Aliphatics
- Esters
- Organic Fluorides
- Synthetic Organic Chemistry
- Pharmaceutical Intermediates
- Fluorochemicals
- top
- bc0001
- 372-31-6
- Mol File:
- 372-31-6.mol
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Ethyl 4,4,4-trifluoroacetoacetate Chemical Properties
- Melting point:
- -39 °C
- Boiling point:
- 129-130 °C(lit.)
- Density
- 1.259 g/mL at 25 °C(lit.)
- vapor pressure
- 8hPa at 20℃
- refractive index
- n20/D 1.375(lit.)
- Flash point:
- 84 °F
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- 10g/l
- form
- Liquid
- pka
- 7.76±0.10(Predicted)
- Specific Gravity
- 1.259 (20/4℃)
- color
- Clear colorless to slightly yellow
- PH
- 6.2 (10g/l, H2O, 20℃)
- Water Solubility
- 10 g/L (20 ºC)
- BRN
- 608353
- InChIKey
- OCJKUQIPRNZDTK-UHFFFAOYSA-N
- CAS DataBase Reference
- 372-31-6(CAS DataBase Reference)
- NIST Chemistry Reference
- Butanoic acid, 4,4,4-trifluoro-3-oxo-, ethyl ester(372-31-6)
- EPA Substance Registry System
- Ethyl 4,4,4-trifluoroacetoacetate (372-31-6)
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Safety Information
- Hazard Codes
- Xn,F,C,Xi
- Risk Statements
- 10-22-52/53
- Safety Statements
- 61-16
- RIDADR
- UN 3272 3/PG 3
- WGK Germany
- 2
- Hazard Note
- Flammable/Corrosive
- TSCA
- T
- HazardClass
- 3
- PackingGroup
- III
- HS Code
- 29183000
MSDS
- Language:English Provider:Ethyl 3-oxo-4,4,4-trifluoroacetoacetate
- Language:English Provider:SigmaAldrich
- Language:English Provider:ACROS
- Language:English Provider:ALFA
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Ethyl 4,4,4-trifluoroacetoacetate Usage And Synthesis
Chemical Properties
Clear liquid
Uses
Intermediate for agro chemicals and pharmaceuticals (mefloquine). Product Data Sheet
Uses
Ethyl 4,4,4-trifluoroacetoacetate is used in the synthesis of fluorinated 2-thiouracil analogs as antithyroid agents.
Uses
Widely used in the synthetic process of medicine, pesticides and organic intermediate.
Flammability and Explosibility
Flammable
Synthesis
With an ethanol solution of sodium ethoxide as a catalyst and in the presence of an organic solvent, ethyl trifluoroacetate and ethyl acetate are subjected to a Claisen condensation reaction, and ethyl 4,4,4-trifluoroacetoacetate is synthesized.
Ethyl 4,4,4-trifluoroacetoacetate Preparation Products And Raw materials
Raw materials
Preparation Products
4-BROMO-6-(TRIFLUOROMETHYL)PYRIMIDINE5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE4-(Trifluoromethyl)-2-(methylthio)pyrimidine-5-carboxylic acid ,97%5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXAMIDE4-TRIFLUOROMETHYL-QUINOLINE-2-CARBOXYLIC ACID6-Fluoro-4-(trifluoromethyl)quinolin-2-amine ,97%ethyl 2-(methylsulfanyl)-4-(trifluoromethyl)pyrimidine-5-carboxylate4-(Trifluoromethyl)quinoline-2-carbohydrazide ,97%(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANOL4-(Trifluoromethyl)quinolin-2-amine5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE(4-(Trifluoromethyl)quinolin-2-yl)methanol ,97%(6-Fluoro-4-(trifluoromethyl)quinolin-2-yl)methanol ,97%1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE(1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANOL(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL7-HYDROXY-4-(TRIFLUOROMETHYL)COUMARIN4-HYDROXY-2-(METHYLTHIO)-6-(TRIFLUOROMETHYL)PYRIMIDINE4-BROMO-6-FLUORO-2-(TRIFLUOROMETHYL)QUINOLINE1-PHENYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACIDETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE4-MethylpyrimidineETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE4-bromo-2-(trifluoromethyl)quinolineEthyl 6-fluoro-4-(trifluoromethyl)quinoline-2-carboxylate ,97%4-HYDROXY-2-METHYL-6-TRIFLUOROMETHYLPYRIMIDINE2,6-BIS(TRIFLUOROMETHYL)-4-HYDROXYQUINOLINEETHYL 3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-3-OL2-BROMO-4-(TRIFLUOROMETHYL)QUINOLINE2-Bromo-6-fluoro-4-(trifluoromethyl)quinoline4-HYDROXY-2-(TRIFLUOROMETHYL)QUINOLINEEthyl 3-amino-4,4,4-trifluorocrotonate
Ethyl 4,4,4-trifluoroacetoacetateSupplier
Nanjing Yihua Biotechnology Co., Ltd Gold
- Tel
- 15850730945; 15850730945
- 1334103687@qq.com
Shandong Zhanhua Yonghao Pharmaceutical Technology Co., Ltd Gold
- Tel
- 0576-0576-88685096 13989620089
- sales@yfchem.cn
Mashilabs (Shanghai) Co.,Ltd. Gold
- Tel
- 021-00000000 19916721580
- info@mashilabs.com
Shanghai Yihe Biological Technology Co., Ltd. Gold
- Tel
- 17721395025
- 2423903095@qq.com
XIANJU DOEASTCHEM Co., Ltd. Gold
- Tel
- 0576-87788985 13586230158
- 504833149@qq.com
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Ethyl 4,4,4-trifluoroacetoacetate(372-31-6)Related Product Information
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