Ethyl 2-methylacetoacetate Chemical Properties

Melting point:

-45 °C

Boiling point:

187 °C (lit.)

Density 

1.019 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.418(lit.)

Flash point:

145 °F

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Chloroform (Slightly), Methanol (Slightly)

pka

11.98±0.46(Predicted)

form 

Liquid

Specific Gravity

1.019

color 

Clear colorless to yellow

Water Solubility 

IMMISCIBLE

BRN 

1071742

LogP

1.063 (est)

CAS DataBase Reference

609-14-3(CAS DataBase Reference)

NIST Chemistry Reference

Butanoic acid, 2-methyl-3-oxo-, ethyl ester(609-14-3)

EPA Substance Registry System

Butanoic acid, 2-methyl-3-oxo-, ethyl ester (609-14-3)

Safety Information

Safety Statements 

24/25

RIDADR 

1993

WGK Germany 

3

TSCA 

Yes

HS Code 

29182300

MSDS

• Language:English Provider:2-Methylacetoacetic acid ethyl ester
• Language:English Provider:ACROS
• Language:English Provider:SigmaAldrich
• Language:English Provider:ALFA

Ethyl 2-methylacetoacetate Usage And Synthesis

Chemical Properties

clear colorless to yellow liquid

Uses

Ethyl 2-methylacetoacetate is used in Japp-Klingemann reaction to prepare hydrazones from beta-keto acid and aryl diazonium salts. It is used as a precursor involved in the synthesis of ethylpyruvate phenylhydrazone via reaction with benzenediazonium chloride.

Uses

• Ethyl 2-methylacetoacetate is used as a substrate in the rhenium-catalyzed synthesis of multisubstituted aromatic compounds.
• It can be employed in the synthesis of coumarin derivatives via Pechmann condensation.
• It undergoes dehydration to yield conjugated alkynyl and allenyl esters.
• It is also used in the total synthesis of chlorotonil A, yangjinhualine A, (+)- and (?)-saudin.

Ethyl 2-methylacetoacetate(609-14-3)Related Product Information

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