Basic information Safety Supplier Related

Asatone

Basic information Safety Supplier Related

Asatone Basic information

Product Name:
Asatone
Synonyms:
  • Asatone
  • 1,4-Ethanonaphthalene-6,10(4H)-dione, 1,4a,5,8a-tetrahydro-1,5,5,7,9,9-hexamethoxy-3,8a-di-2-propen-1-yl-, (1R,4S,4aS,8aS)-rel-
  • Asatone USP/EP/BP
  • Asatone A
  • NF-κB,inhibit,Asatone,Nuclear factor-κB,Inhibitor,Nuclear factor-kappaB
  • rel-(1R,4S,4aS,8aS)-3,8a-Diallyl-1,5,5,7,9,9-hexamethoxy-1,4a,5,8a-tetrahydro-1,4-ethanonaphthalene-6,10(4H)-dione
  • Asatone, 10 mM in DMSO
CAS:
38451-63-7
MF:
C24H32O8
MW:
448.51
Mol File:
38451-63-7.mol
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Asatone Chemical Properties

Boiling point:
536.1±50.0 °C(Predicted)
Density 
1.19±0.1 g/cm3(Predicted)
storage temp. 
4°C, protect from light
solubility 
Soluble in DMSO
form 
Solid
color 
White to off-white
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Asatone Usage And Synthesis

Chemical Properties

Blocky white crystals, soluble in methanol, ethanol, DMSO and other organic solvents, derived from AsarumsieboldiiMiq.

Uses

Asatone is an active component isolated from Radix et Rhizoma Asari, with anti-inflammatory effect via activation of NF-κB and donwn regulation of p-MAPK (ERK, JNK and p38) pathways[1].

Biological Activity

Asatone, an active ingredient isolated from Asarum, has anti-inflammatory activity by activating NF-κB and downregulating p-MAPK (ERK, JNK and p38) pathways.

target

NF-κB

References

[1] Chang HY, et al. Asatone Prevents Acute Lung Injury by Reducing Expressions of NF-[Formula: see text]B, MAPK and Inflammatory Cytokines. Am J Chin Med. 2018;46(3):651-671. DOI:10.1142/S0192415X18500349

AsatoneSupplier

BioBioPha Co., Ltd.
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0871-65217109 13211707573;
Email
y.liu@mail.biobiopha.com
ShangHai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847 13636370518
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shyysw007@163.com
Chengdu Biopurify Phytochemicals Ltd.
Tel
+86-028-82633397 18982077548
Email
cwb1@biopurify.cn
Shanghai Tauto Biotech Co., Ltd.
Tel
021-51320588
Email
tauto@tautobiotech.com
Chengdu Herbpurify Co.Ltd.
Tel
2355253622; 18981954830
Email
2355253622@qq.com;
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Asatone(38451-63-7)Related Product Information