Basic information Safety Supplier Related

1-Caffeoylquinic acid

Basic information Safety Supplier Related

1-Caffeoylquinic acid Basic information

Product Name:
1-Caffeoylquinic acid
Synonyms:
  • 1-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4,5-trihydroxy-,(1a,3R,4a,5R)
  • 1-Caffeoylquinic acid
  • 3,4-Dihydroxycinnamic acid (-)-1-carboxy-3,4,5-trihydroxycyclohexyl ester
  • 1-O-caffeoylquinic acid
  • Cyclohexanecarboxylic acid, 1-[[3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]oxy]-3,4,5-trihydroxy-, (1α,3R,4α,5R)-
  • 1-Caffeoylquinicaci
  • 1-Kaffeylchinasaeure
  • 1-{[(2E)-3-(3,4-Dihydroxyphenyl)-2-propenoyl]oxy}-3,4,5-trihydroxycyclohexanecarboxylic acid
CAS:
1241-87-8
MF:
C16H18O9
MW:
354.31
Product Categories:
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
Mol File:
1241-87-8.mol
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1-Caffeoylquinic acid Chemical Properties

Boiling point:
636.2±55.0 °C(Predicted)
Density 
1.65
storage temp. 
4°C, protect from light
solubility 
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form 
powder
pka
2.94±0.50(Predicted)
color 
White
LogP
-0.587 (est)
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1-Caffeoylquinic acid Usage And Synthesis

Chemical Properties

Earthy yellow crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from honeysuckle.

Uses

1-Caffeoylquinic Acid can be useful in valorization, green extraction development, and metabolomic analysis of wild artichoke byproduct using pressurized liquid extraction UPLC-HRMS and multivariate data analysis.

Definition

ChEBI: 1-O-caffeoylquinic acid is an alkyl caffeate ester obtained by the formal condensation of the carboxy group of trans-caffeic acid with the 1-hydroxy group of (-)-quinic acid. It has a role as a Camellia sinensis metabolite, a NF-kappaB inhibitor, an antineoplastic agent and an antioxidant. It is a quinic acid and an alkyl caffeate ester. It is functionally related to a trans-caffeic acid. It derives from a hydride of a (-)-quinic acid.

Biological Activity

1-Caffeoylquinic acid 1-Caffeoylquinic acid is a potent NF-κB inhibitor, showing high binding affinity to the RH domain of p105 with a Ki value of 0.002 μM and a binding energy of 1.50 Kcal/mol. 1-Caffeoylquinic acid has the ability to resist oxidative stress. 1-Caffeoylquinic acid inhibits PD-1/PD-L1 interaction.

target

Ki: 0.002 μM (1-Caffeoylquinic acid)

1-Caffeoylquinic acidSupplier

Shandong Xiya Chemical Co., Ltd
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13355009207 13355009207
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Chengdu Biopurify Phytochemicals Ltd.
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+86-028-82633397 18982077548
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cwb1@biopurify.cn
Beijing HuaMeiHuLiBiological Chemical
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010-56205725
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waley188@sohu.com
Shanghai Ruji Biology Technology Co., Ltd.
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+86-21-65211385-8001 36031160
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sales@shruji.com
TargetMol Chemicals Inc.
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021-33632979 15002134094
Email
marketing@targetmol.com
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1-Caffeoylquinic acid(1241-87-8)Related Product Information